EcoR1 Capital, LLC Quant / Systematic

CIK: 0001587114 · Show all filings

Period: Q2 2016 (← Previous) (Next →)

Filing Date: Aug 15, 2016

Total Value ($000): $253,622 (99.7% shares, 0.3% debt)

Holdings (32)

IRWD IRONWOOD PHARMACEUTICALS INC 12.5%

Value ($000) $31,778 Shares 2,430,451 Est. Cost $8.96 Unrealized +9.1%

GLPG GALAPAGOS NV 9.6%

Value ($000) $24,373 Shares 439,385 Est. Cost $55.83 Unrealized —

— RETROPHIN INC 8.6%

Value ($000) $21,819 Shares 1,225,084 Est. Cost $21.12 Unrealized —

CYTK CYTOKINETICS INC 8.0%

Value ($000) $20,306 Shares 2,139,697 Est. Cost $9.00 Unrealized -8.8%

— ASSEMBLY BIOSCIENCES INC 6.4%

Value ($000) $16,335 Shares 2,943,164 Est. Cost $8.38 Unrealized —

— FIBROGEN INC 5.1%

Value ($000) $12,943 Shares 788,745 Est. Cost $24.72 Unrealized —

— ACCELERON PHARMA INC 5.0%

Value ($000) $12,620 Shares 371,381 Est. Cost $28.46 Unrealized —

— GILEAD SCIENCES INC 4.9%

Value ($000) $12,513 Shares 150,000 Est. Cost — Unrealized —

— ALLERGAN PLC 4.6%

Value ($000) $11,555 Shares 50,000 Est. Cost — Unrealized —

— INTRA CELLULAR THERAPIES INC 3.7%

Value ($000) $9,509 Shares 244,950 Est. Cost $38.82 Unrealized —

— DERMIRA INC 3.1%

Value ($000) $7,956 Shares 272,000 Est. Cost $29.25 Unrealized —

— EPIZYME INC 3.0%

Value ($000) $7,732 Shares 755,046 Est. Cost $15.17 Unrealized —

— IRONWOOD PHARMACEUTICALS INC 3.0%

Value ($000) $7,606 Shares 581,500 Est. Cost — Unrealized —

KURA KURA ONCOLOGY INC 2.6%

Value ($000) $6,681 Shares 2,465,286 Est. Cost $10.42 Unrealized -70.2%

NTLA INTELLIA THERAPEUTICS INC 2.6%

Value ($000) $6,633 Shares 310,695 Est. Cost $26.61 Unrealized 0.0%

— ACHAOGEN INC 2.3%

Value ($000) $5,957 Shares 1,571,708 Est. Cost $3.79 Unrealized —

ONC BEIGENE LTD 2.1%

Value ($000) $5,226 Shares 175,380 Est. Cost $29.75 Unrealized —

— KINDRED BIOSCIENCES INC 2.0%

Value ($000) $5,072 Shares 1,432,765 Est. Cost $7.10 Unrealized —

— NABRIVA THERAPEUTICS AG 1.7%

Value ($000) $4,221 Shares 562,741 Est. Cost $9.50 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 1.4%

Value ($000) $3,520 Shares 357,365 Est. Cost $12.54 Unrealized +9.3%

COLL COLLEGIUM PHARMACEUTICAL INC 1.3%

Value ($000) $3,339 Shares 281,776 Est. Cost $17.31 Unrealized -4.6%

XNCR XENCOR INC 1.3%

Value ($000) $3,190 Shares 168,000 Est. Cost $13.71 Unrealized 0.0%

ENTA ENANTA PHARMACEUTICALS INC 1.2%

Value ($000) $3,018 Shares 136,882 Est. Cost $27.84 Unrealized -6.0%

EDIT EDITAS MEDICINE INC 0.8%

Value ($000) $2,085 Shares 85,469 Est. Cost $26.29 Unrealized +28.3%

— ARRAY BIOPHARMA INC 0.7%

Value ($000) $1,851 Shares 520,000 Est. Cost — Unrealized —

— FORWARD PHARMA A/S 0.6%

Value ($000) $1,532 Shares 84,332 Est. Cost $23.61 Unrealized —

— IMMUNOGEN INC 0.4%

Value ($000) $922 Shares 299,500 Est. Cost — Unrealized —

— AKARI THERAPEUTICS PLC 0.3%

Value ($000) $856 Shares 63,468 Est. Cost $24.00 Unrealized —

— TESARO INC 0.3%

Value ($000) $773 Shares 9,200 Est. Cost $84.02 Unrealized —

— ADVAXIS INC 0.3%

Value ($000) $751 Shares 92,800 Est. Cost $8.09 Unrealized —

— TARGACEPT INC 0.3%

Value ($000) $669 Shares 669,166 Est. Cost $1.00 Unrealized —

— EIGER BIOPHARMACEUTICALS INC 0.1%

Value ($000) $281 Shares 14,190 Est. Cost $16.77 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
IRWD	IRONWOOD PHARMACEUTICALS INC	2,430,451	$31,778	12.5%	$8.96	+9.1%	COM	46333X108
GLPG	GALAPAGOS NV	439,385	$24,373	9.6%	$55.83	—	SPONSORED ADR	36315X101
—	RETROPHIN INC	1,225,084	$21,819	8.6%	$21.12	—	COM	761299106
CYTK	CYTOKINETICS INC	2,139,697	$20,306	8.0%	$9.00	-8.8%	COM	23282W605
—	ASSEMBLY BIOSCIENCES INC	2,943,164	$16,335	6.4%	$8.38	—	COM	045396108
—	FIBROGEN INC	788,745	$12,943	5.1%	$24.72	—	COM	31572Q808
—	ACCELERON PHARMA INC	371,381	$12,620	5.0%	$28.46	—	COM	00434H108
—	GILEAD SCIENCES INC	150,000	$12,513	4.9%	—	—	Call	375558903
—	ALLERGAN PLC	50,000	$11,555	4.6%	—	—	Call	G0177J908
—	INTRA CELLULAR THERAPIES INC	244,950	$9,509	3.7%	$38.82	—	COM	46116X101
—	DERMIRA INC	272,000	$7,956	3.1%	$29.25	—	COM	24983L104
—	EPIZYME INC	755,046	$7,732	3.0%	$15.17	—	COM	29428V104
—	IRONWOOD PHARMACEUTICALS INC	581,500	$7,606	3.0%	—	—	Call	46333X908
KURA	KURA ONCOLOGY INC	2,465,286	$6,681	2.6%	$10.42	-70.2%	COM	50127T109
NTLA	INTELLIA THERAPEUTICS INC	310,695	$6,633	2.6%	$26.61	0.0%	COM	45826J105
—	ACHAOGEN INC	1,571,708	$5,957	2.3%	$3.79	—	COM	004449104
ONC	BEIGENE LTD	175,380	$5,226	2.1%	$29.75	—	SPONSORED ADR	07725L102
—	KINDRED BIOSCIENCES INC	1,432,765	$5,072	2.0%	$7.10	—	COM	494577109
—	NABRIVA THERAPEUTICS AG	562,741	$4,221	1.7%	$9.50	—	SPONSORED ADR	62957M104
SNDX	SYNDAX PHARMACEUTICALS INC	357,365	$3,520	1.4%	$12.54	+9.3%	COM	87164F105
COLL	COLLEGIUM PHARMACEUTICAL INC	281,776	$3,339	1.3%	$17.31	-4.6%	COM	19459J104
XNCR	XENCOR INC	168,000	$3,190	1.3%	$13.71	0.0%	COM	98401F105
ENTA	ENANTA PHARMACEUTICALS INC	136,882	$3,018	1.2%	$27.84	-6.0%	COM	29251M106
EDIT	EDITAS MEDICINE INC	85,469	$2,085	0.8%	$26.29	+28.3%	COM	28106W103
—	ARRAY BIOPHARMA INC	520,000	$1,851	0.7%	—	—	Call	04269X905
—	FORWARD PHARMA A/S	84,332	$1,532	0.6%	$23.61	—	SPONSORED ADR	34986J105
—	IMMUNOGEN INC	299,500	$922	0.4%	—	—	Call	45253H901
—	AKARI THERAPEUTICS PLC	63,468	$856	0.3%	$24.00	—	SPONSORED ADR	00972G108
—	TESARO INC	9,200	$773	0.3%	$84.02	—	COM	881569107
—	ADVAXIS INC	92,800	$751	0.3%	$8.09	—	COM	007624208
—	TARGACEPT INC	669,166	$669	0.3%	$1.00	—	NOTE	87611RAA6
—	EIGER BIOPHARMACEUTICALS INC	14,190	$281	0.1%	$16.77	—	COM	28249U105