EcoR1 Capital, LLC Quant / Systematic

Location: San Francisco, CA

CIK: 0001587114 · Show all filings

Period: Q3 2016 (← Previous) (Next →)

Filing Date: Nov 14, 2016

Total Value: $326M (100.0% shares, 0.0% debt)

Holdings (31)

IRWD IRONWOOD PHARMACEUTICALS INC 13.7%

Value $44.63M Shares 2,810,315 Est. Cost $9.33 Unrealized +25.3%

GLPG GALAPAGOS NV 9.9%

Value $32.37M Shares 500,576 Est. Cost $56.91 Unrealized —

— BRISTOL MYERS SQUIBB CO 8.3%

Value $26.96M Shares 500,000 Est. Cost — Unrealized —

— ASSEMBLY BIOSCIENCES INC 6.5%

Value $21.22M Shares 2,943,164 Est. Cost $8.38 Unrealized —

— DERMIRA INC 5.4%

Value $17.65M Shares 522,000 Est. Cost $31.44 Unrealized —

ARDX ARDELYX INC 5.2%

Value $16.95M Shares 1,310,023 Est. Cost $10.48 Unrealized 0.0%

KURA KURA ONCOLOGY INC 5.0%

Value $16.32M Shares 2,611,906 Est. Cost $10.12 Unrealized -49.9%

— FIVE PRIME THERAPEUTICS INC 4.6%

Value $15.04M Shares 286,612 Est. Cost $52.49 Unrealized —

— FIBROGEN INC 4.4%

Value $14.2M Shares 686,184 Est. Cost $24.72 Unrealized —

— GILEAD SCIENCES INC 3.6%

Value $11.87M Shares 150,000 Est. Cost — Unrealized —

— ALLERGAN PLC 3.5%

Value $11.52M Shares 50,000 Est. Cost — Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 3.2%

Value $10.56M Shares 200,000 Est. Cost $43.55 Unrealized 0.0%

— PROTEOSTASIS THERAPEUTICS INC 2.9%

Value $9.39M Shares 602,315 Est. Cost $15.59 Unrealized —

— EXACT SCIENCES CORP 2.8%

Value $9.285M Shares 500,000 Est. Cost — Unrealized —

— ACHAOGEN INC 2.5%

Value $8.046M Shares 1,679,707 Est. Cost $3.85 Unrealized —

CYTK CYTOKINETICS INC 2.4%

Value $7.772M Shares 846,654 Est. Cost $9.00 Unrealized +16.0%

— KINDRED BIOSCIENCES INC 2.2%

Value $7.149M Shares 1,432,765 Est. Cost $7.10 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 1.7%

Value $5.418M Shares 357,365 Est. Cost $12.54 Unrealized +4.9%

ONC BEIGENE LTD 1.5%

Value $5.037M Shares 163,470 Est. Cost $29.75 Unrealized —

— IRONWOOD PHARMACEUTICALS INC 1.4%

Value $4.47M Shares 281,500 Est. Cost — Unrealized —

ASND ASCENDIS PHARMA A S 1.4%

Value $4.406M Shares 219,200 Est. Cost $20.10 Unrealized —

— SPARK THERAPEUTICS INC 1.3%

Value $4.12M Shares 68,600 Est. Cost $60.06 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 1.2%

Value $3.889M Shares 946,263 Est. Cost $4.11 Unrealized —

— NABRIVA THERAPEUTICS AG 1.2%

Value $3.87M Shares 548,912 Est. Cost $9.50 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 1.0%

Value $3.419M Shares 200,858 Est. Cost $26.61 Unrealized -27.2%

— CHIMERIX INC 1.0%

Value $3.313M Shares 598,062 Est. Cost $5.54 Unrealized —

— ONCOMED PHARMACEUTICALS INC 0.9%

Value $3.038M Shares 265,784 Est. Cost $11.43 Unrealized —

FATE FATE THERAPEUTICS INC 0.6%

Value $1.842M Shares 590,527 Est. Cost $2.43 Unrealized 0.0%

— CHEMOCENTRYX INC 0.3%

Value $1.075M Shares 178,000 Est. Cost $6.04 Unrealized —

— SYROS PHARMACEUTICALS INC 0.3%

Value $882K Shares 63,596 Est. Cost $13.87 Unrealized —

— CASCADIAN THERAPEUTICS INC 0.1%

Value $170K Shares 103,800 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
IRWD	IRONWOOD PHARMACEUTICALS INC	2,810,315	$44.63M	13.7%	$9.33	+25.3%	COM	46333X108
GLPG	GALAPAGOS NV	500,576	$32.37M	9.9%	$56.91	—	SPONSORED ADR	36315X101
—	BRISTOL MYERS SQUIBB CO	500,000	$26.96M	8.3%	—	—	Call	110122908
—	ASSEMBLY BIOSCIENCES INC	2,943,164	$21.22M	6.5%	$8.38	—	COM	045396108
—	DERMIRA INC	522,000	$17.65M	5.4%	$31.44	—	COM	24983L104
ARDX	ARDELYX INC	1,310,023	$16.95M	5.2%	$10.48	0.0%	COM	039697107
KURA	KURA ONCOLOGY INC	2,611,906	$16.32M	5.0%	$10.12	-49.9%	COM	50127T109
—	FIVE PRIME THERAPEUTICS INC	286,612	$15.04M	4.6%	$52.49	—	COM	33830X104
—	FIBROGEN INC	686,184	$14.2M	4.4%	$24.72	—	COM	31572Q808
—	GILEAD SCIENCES INC	150,000	$11.87M	3.6%	—	—	Call	375558903
—	ALLERGAN PLC	50,000	$11.52M	3.5%	—	—	Call	G0177J908
AGIO	AGIOS PHARMACEUTICALS INC	200,000	$10.56M	3.2%	$43.55	0.0%	COM	00847X104
—	PROTEOSTASIS THERAPEUTICS INC	602,315	$9.39M	2.9%	$15.59	—	COM	74373B109
—	EXACT SCIENCES CORP	500,000	$9.285M	2.8%	—	—	Put	30063P955
—	ACHAOGEN INC	1,679,707	$8.046M	2.5%	$3.85	—	COM	004449104
CYTK	CYTOKINETICS INC	846,654	$7.772M	2.4%	$9.00	+16.0%	COM	23282W605
—	KINDRED BIOSCIENCES INC	1,432,765	$7.149M	2.2%	$7.10	—	COM	494577109
SNDX	SYNDAX PHARMACEUTICALS INC	357,365	$5.418M	1.7%	$12.54	+4.9%	COM	87164F105
ONC	BEIGENE LTD	163,470	$5.037M	1.5%	$29.75	—	SPONSORED ADR	07725L102
—	IRONWOOD PHARMACEUTICALS INC	281,500	$4.47M	1.4%	—	—	Call	46333X908
ASND	ASCENDIS PHARMA A S	219,200	$4.406M	1.4%	$20.10	—	SPONSORED ADR	04351P101
—	SPARK THERAPEUTICS INC	68,600	$4.12M	1.3%	$60.06	—	COM	84652J103
—	ADVERUM BIOTECHNOLOGIES INC	946,263	$3.889M	1.2%	$4.11	—	COM	00773U108
—	NABRIVA THERAPEUTICS AG	548,912	$3.87M	1.2%	$9.50	—	SPONSORED ADR	62957M104
NTLA	INTELLIA THERAPEUTICS INC	200,858	$3.419M	1.0%	$26.61	-27.2%	COM	45826J105
—	CHIMERIX INC	598,062	$3.313M	1.0%	$5.54	—	COM	16934W106
—	ONCOMED PHARMACEUTICALS INC	265,784	$3.038M	0.9%	$11.43	—	COM	68234X102
FATE	FATE THERAPEUTICS INC	590,527	$1.842M	0.6%	$2.43	0.0%	COM	31189P102
—	CHEMOCENTRYX INC	178,000	$1.075M	0.3%	$6.04	—	COM	01683L106
—	SYROS PHARMACEUTICALS INC	63,596	$882K	0.3%	$13.87	—	COM	87184Q107
—	CASCADIAN THERAPEUTICS INC	103,800	$170K	0.1%	—	—	Call	14740B901