EcoR1 Capital, LLC Quant / Systematic

CIK: 0001587114 · Show all filings

Period: Q3 2016 (← Previous) (Next →)

Filing Date: Nov 14, 2016

Total Value ($000): $325,892 (100.0% shares, 0.0% debt)

Holdings (31)

IRWD IRONWOOD PHARMACEUTICALS INC 13.7%

Value ($000) $44,628 Shares 2,810,315 Est. Cost $9.33 Unrealized +25.3%

GLPG GALAPAGOS NV 9.9%

Value ($000) $32,367 Shares 500,576 Est. Cost $56.91 Unrealized —

— BRISTOL MYERS SQUIBB CO 8.3%

Value ($000) $26,960 Shares 500,000 Est. Cost — Unrealized —

— ASSEMBLY BIOSCIENCES INC 6.5%

Value ($000) $21,220 Shares 2,943,164 Est. Cost $8.38 Unrealized —

— DERMIRA INC 5.4%

Value ($000) $17,654 Shares 522,000 Est. Cost $31.44 Unrealized —

ARDX ARDELYX INC 5.2%

Value ($000) $16,952 Shares 1,310,023 Est. Cost $10.48 Unrealized 0.0%

KURA KURA ONCOLOGY INC 5.0%

Value ($000) $16,324 Shares 2,611,906 Est. Cost $10.12 Unrealized -49.9%

— FIVE PRIME THERAPEUTICS INC 4.6%

Value ($000) $15,044 Shares 286,612 Est. Cost $52.49 Unrealized —

— FIBROGEN INC 4.4%

Value ($000) $14,204 Shares 686,184 Est. Cost $24.72 Unrealized —

— GILEAD SCIENCES INC 3.6%

Value ($000) $11,868 Shares 150,000 Est. Cost — Unrealized —

— ALLERGAN PLC 3.5%

Value ($000) $11,516 Shares 50,000 Est. Cost — Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 3.2%

Value ($000) $10,564 Shares 200,000 Est. Cost $43.55 Unrealized 0.0%

— PROTEOSTASIS THERAPEUTICS INC 2.9%

Value ($000) $9,390 Shares 602,315 Est. Cost $15.59 Unrealized —

— EXACT SCIENCES CORP 2.8%

Value ($000) $9,285 Shares 500,000 Est. Cost — Unrealized —

— ACHAOGEN INC 2.5%

Value ($000) $8,046 Shares 1,679,707 Est. Cost $3.85 Unrealized —

CYTK CYTOKINETICS INC 2.4%

Value ($000) $7,772 Shares 846,654 Est. Cost $9.00 Unrealized +16.0%

— KINDRED BIOSCIENCES INC 2.2%

Value ($000) $7,149 Shares 1,432,765 Est. Cost $7.10 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 1.7%

Value ($000) $5,418 Shares 357,365 Est. Cost $12.54 Unrealized +4.9%

ONC BEIGENE LTD 1.5%

Value ($000) $5,037 Shares 163,470 Est. Cost $29.75 Unrealized —

— IRONWOOD PHARMACEUTICALS INC 1.4%

Value ($000) $4,470 Shares 281,500 Est. Cost — Unrealized —

ASND ASCENDIS PHARMA A S 1.4%

Value ($000) $4,406 Shares 219,200 Est. Cost $20.10 Unrealized —

— SPARK THERAPEUTICS INC 1.3%

Value ($000) $4,120 Shares 68,600 Est. Cost $60.06 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 1.2%

Value ($000) $3,889 Shares 946,263 Est. Cost $4.11 Unrealized —

— NABRIVA THERAPEUTICS AG 1.2%

Value ($000) $3,870 Shares 548,912 Est. Cost $9.50 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 1.0%

Value ($000) $3,419 Shares 200,858 Est. Cost $26.61 Unrealized -27.2%

— CHIMERIX INC 1.0%

Value ($000) $3,313 Shares 598,062 Est. Cost $5.54 Unrealized —

— ONCOMED PHARMACEUTICALS INC 0.9%

Value ($000) $3,038 Shares 265,784 Est. Cost $11.43 Unrealized —

FATE FATE THERAPEUTICS INC 0.6%

Value ($000) $1,842 Shares 590,527 Est. Cost $2.43 Unrealized 0.0%

— CHEMOCENTRYX INC 0.3%

Value ($000) $1,075 Shares 178,000 Est. Cost $6.04 Unrealized —

— SYROS PHARMACEUTICALS INC 0.3%

Value ($000) $882 Shares 63,596 Est. Cost $13.87 Unrealized —

— CASCADIAN THERAPEUTICS INC 0.1%

Value ($000) $170 Shares 103,800 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
IRWD	IRONWOOD PHARMACEUTICALS INC	2,810,315	$44,628	13.7%	$9.33	+25.3%	COM	46333X108
GLPG	GALAPAGOS NV	500,576	$32,367	9.9%	$56.91	—	SPONSORED ADR	36315X101
—	BRISTOL MYERS SQUIBB CO	500,000	$26,960	8.3%	—	—	Call	110122908
—	ASSEMBLY BIOSCIENCES INC	2,943,164	$21,220	6.5%	$8.38	—	COM	045396108
—	DERMIRA INC	522,000	$17,654	5.4%	$31.44	—	COM	24983L104
ARDX	ARDELYX INC	1,310,023	$16,952	5.2%	$10.48	0.0%	COM	039697107
KURA	KURA ONCOLOGY INC	2,611,906	$16,324	5.0%	$10.12	-49.9%	COM	50127T109
—	FIVE PRIME THERAPEUTICS INC	286,612	$15,044	4.6%	$52.49	—	COM	33830X104
—	FIBROGEN INC	686,184	$14,204	4.4%	$24.72	—	COM	31572Q808
—	GILEAD SCIENCES INC	150,000	$11,868	3.6%	—	—	Call	375558903
—	ALLERGAN PLC	50,000	$11,516	3.5%	—	—	Call	G0177J908
AGIO	AGIOS PHARMACEUTICALS INC	200,000	$10,564	3.2%	$43.55	0.0%	COM	00847X104
—	PROTEOSTASIS THERAPEUTICS INC	602,315	$9,390	2.9%	$15.59	—	COM	74373B109
—	EXACT SCIENCES CORP	500,000	$9,285	2.8%	—	—	Put	30063P955
—	ACHAOGEN INC	1,679,707	$8,046	2.5%	$3.85	—	COM	004449104
CYTK	CYTOKINETICS INC	846,654	$7,772	2.4%	$9.00	+16.0%	COM	23282W605
—	KINDRED BIOSCIENCES INC	1,432,765	$7,149	2.2%	$7.10	—	COM	494577109
SNDX	SYNDAX PHARMACEUTICALS INC	357,365	$5,418	1.7%	$12.54	+4.9%	COM	87164F105
ONC	BEIGENE LTD	163,470	$5,037	1.5%	$29.75	—	SPONSORED ADR	07725L102
—	IRONWOOD PHARMACEUTICALS INC	281,500	$4,470	1.4%	—	—	Call	46333X908
ASND	ASCENDIS PHARMA A S	219,200	$4,406	1.4%	$20.10	—	SPONSORED ADR	04351P101
—	SPARK THERAPEUTICS INC	68,600	$4,120	1.3%	$60.06	—	COM	84652J103
—	ADVERUM BIOTECHNOLOGIES INC	946,263	$3,889	1.2%	$4.11	—	COM	00773U108
—	NABRIVA THERAPEUTICS AG	548,912	$3,870	1.2%	$9.50	—	SPONSORED ADR	62957M104
NTLA	INTELLIA THERAPEUTICS INC	200,858	$3,419	1.0%	$26.61	-27.2%	COM	45826J105
—	CHIMERIX INC	598,062	$3,313	1.0%	$5.54	—	COM	16934W106
—	ONCOMED PHARMACEUTICALS INC	265,784	$3,038	0.9%	$11.43	—	COM	68234X102
FATE	FATE THERAPEUTICS INC	590,527	$1,842	0.6%	$2.43	0.0%	COM	31189P102
—	CHEMOCENTRYX INC	178,000	$1,075	0.3%	$6.04	—	COM	01683L106
—	SYROS PHARMACEUTICALS INC	63,596	$882	0.3%	$13.87	—	COM	87184Q107
—	CASCADIAN THERAPEUTICS INC	103,800	$170	0.1%	—	—	Call	14740B901