Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q3 2018 (← Previous) (Next →)

Filing Date: Nov 14, 2018

Total Value ($000): $822,765 (100.0% shares, 0.0% debt)

Holdings (36)

— LOXO ONCOLOGY INC 7.5%

Value ($000) $61,499 Shares 360,000 Est. Cost $28.44 Unrealized —

— BLUEPRINT MEDICINES CORP 7.1%

Value ($000) $58,545 Shares 750,000 Est. Cost $53.83 Unrealized —

— MYOKARDIA INC 6.4%

Value ($000) $52,486 Shares 805,000 Est. Cost $30.98 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 5.4%

Value ($000) $44,712 Shares 579,776 Est. Cost $66.22 Unrealized +21.5%

— SAGE THERAPEUTICS INC 5.4%

Value ($000) $44,070 Shares 312,000 Est. Cost $70.16 Unrealized —

BLFS BIOLIFE SOLUTIONS INC 5.2%

Value ($000) $42,500 Shares 2,428,571 Est. Cost $15.38 Unrealized +28.6%

FATE FATE THERAPEUTICS INC 5.0%

Value ($000) $41,540 Shares 2,550,000 Est. Cost $4.33 Unrealized +173.2%

— INVITAE CORP 4.9%

Value ($000) $40,152 Shares 2,400,000 Est. Cost $16.73 Unrealized —

— BLUEBIRD BIO INC 4.6%

Value ($000) $37,668 Shares 258,000 Est. Cost $130.95 Unrealized —

— SPARK THERAPEUTICS INC 4.5%

Value ($000) $36,821 Shares 675,000 Est. Cost $57.42 Unrealized —

CDXS CODEXIS INC 4.2%

Value ($000) $34,729 Shares 2,025,000 Est. Cost $5.90 Unrealized +173.6%

SGMO SANGAMO THERAPEUTICS INC 4.1%

Value ($000) $33,900 Shares 2,000,000 Est. Cost $8.03 Unrealized +89.3%

— MAGENTA THERAPEUTICS INC 3.3%

Value ($000) $27,032 Shares 2,250,818 Est. Cost $13.36 Unrealized —

ILMN ILLUMINA INC 3.2%

Value ($000) $26,245 Shares 71,500 Est. Cost $196.93 Unrealized +62.7%

— GENMARK DIAGNOSTICS INC 3.1%

Value ($000) $25,725 Shares 3,500,000 Est. Cost $6.86 Unrealized —

— AUDENTES THERAPEUTICS INC 3.0%

Value ($000) $24,744 Shares 625,000 Est. Cost $24.86 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 2.9%

Value ($000) $23,630 Shares 270,000 Est. Cost $85.55 Unrealized +17.6%

VYGR VOYAGER THERAPEUTICS INC 2.6%

Value ($000) $21,474 Shares 1,135,000 Est. Cost $14.86 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 2.0%

Value ($000) $16,720 Shares 440,000 Est. Cost $32.45 Unrealized —

EVH EVOLENT HEALTH INC 1.9%

Value ($000) $15,620 Shares 550,000 Est. Cost $17.59 Unrealized +35.6%

EDIT EDITAS MEDICINE INC 1.8%

Value ($000) $14,637 Shares 460,000 Est. Cost $29.22 Unrealized +10.6%

ONC BEIGENE LTD 1.5%

Value ($000) $12,055 Shares 70,000 Est. Cost $149.93 Unrealized —

— GRITSTONE ONCOLOGY INC 1.2%

Value ($000) $10,261 Shares 720,586 Est. Cost $14.24 Unrealized —

CRSP CRISPR THERAPEUTICS AG 1.2%

Value ($000) $9,757 Shares 220,000 Est. Cost $47.34 Unrealized +10.6%

— CONSTELLATION PHARMCETICLS I 1.1%

Value ($000) $8,848 Shares 1,314,743 Est. Cost $6.73 Unrealized —

OSUR ORASURE TECHNOLOGIES INC 1.0%

Value ($000) $8,111 Shares 525,000 Est. Cost $17.66 Unrealized -7.2%

— HOMOLOGY MEDICINES INC 1.0%

Value ($000) $8,001 Shares 350,000 Est. Cost $21.76 Unrealized —

— CLOVIS ONCOLOGY INC 0.8%

Value ($000) $6,902 Shares 235,000 Est. Cost $69.25 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 0.8%

Value ($000) $6,460 Shares 40,000 Est. Cost $136.70 Unrealized 0.0%

CDNA CAREDX INC 0.7%

Value ($000) $5,770 Shares 200,000 Est. Cost $11.47 Unrealized +63.2%

NEOG NEOGEN CORP 0.6%

Value ($000) $4,649 Shares 65,000 Est. Cost $30.13 Unrealized +41.5%

— CELGENE CORP 0.5%

Value ($000) $4,475 Shares 50,000 Est. Cost — Unrealized —

GILD GILEAD SCIENCES INC 0.5%

Value ($000) $3,861 Shares 50,000 Est. Cost — Unrealized —

CTMX CYTOMX THERAPEUTICS INC 0.5%

Value ($000) $3,839 Shares 207,500 Est. Cost $17.02 Unrealized +33.9%

— NEON THERAPEUTICS INC 0.4%

Value ($000) $2,889 Shares 338,345 Est. Cost $12.60 Unrealized —

— JOUNCE THERAPEUTICS INC 0.3%

Value ($000) $2,438 Shares 375,000 Est. Cost $18.19 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	LOXO ONCOLOGY INC	360,000	$61,499	7.5%	$28.44	—	COM	548862101
—	BLUEPRINT MEDICINES CORP	750,000	$58,545	7.1%	$53.83	—	COM	09627Y109
—	MYOKARDIA INC	805,000	$52,486	6.4%	$30.98	—	COM	62857M105
AGIO	AGIOS PHARMACEUTICALS INC	579,776	$44,712	5.4%	$66.22	+21.5%	COM	00847X104
—	SAGE THERAPEUTICS INC	312,000	$44,070	5.4%	$70.16	—	COM	78667J108
BLFS	BIOLIFE SOLUTIONS INC	2,428,571	$42,500	5.2%	$15.38	+28.6%	COM NEW	09062W204
FATE	FATE THERAPEUTICS INC	2,550,000	$41,540	5.0%	$4.33	+173.2%	COM	31189P102
—	INVITAE CORP	2,400,000	$40,152	4.9%	$16.73	—	COM	46185L103
—	BLUEBIRD BIO INC	258,000	$37,668	4.6%	$130.95	—	COM	09609G100
—	SPARK THERAPEUTICS INC	675,000	$36,821	4.5%	$57.42	—	COM	84652J103
CDXS	CODEXIS INC	2,025,000	$34,729	4.2%	$5.90	+173.6%	COM	192005106
SGMO	SANGAMO THERAPEUTICS INC	2,000,000	$33,900	4.1%	$8.03	+89.3%	COM	800677106
—	MAGENTA THERAPEUTICS INC	2,250,818	$27,032	3.3%	$13.36	—	COM	55910K108
ILMN	ILLUMINA INC	71,500	$26,245	3.2%	$196.93	+62.7%	COM	452327109
—	GENMARK DIAGNOSTICS INC	3,500,000	$25,725	3.1%	$6.86	—	COM	372309104
—	AUDENTES THERAPEUTICS INC	625,000	$24,744	3.0%	$24.86	—	COM	05070R104
ALNY	ALNYLAM PHARMACEUTICALS INC	270,000	$23,630	2.9%	$85.55	+17.6%	COM	02043Q107
VYGR	VOYAGER THERAPEUTICS INC	1,135,000	$21,474	2.6%	$14.86	—	COM	92915B106
—	GLOBAL BLOOD THERAPEUTICS IN	440,000	$16,720	2.0%	$32.45	—	COM	37890U108
EVH	EVOLENT HEALTH INC	550,000	$15,620	1.9%	$17.59	+35.6%	CL A	30050B101
EDIT	EDITAS MEDICINE INC	460,000	$14,637	1.8%	$29.22	+10.6%	COM	28106W103
ONC	BEIGENE LTD	70,000	$12,055	1.5%	$149.93	—	SPONSORED ADR	07725L102
—	GRITSTONE ONCOLOGY INC	720,586	$10,261	1.2%	$14.24	—	COM	39868T105
CRSP	CRISPR THERAPEUTICS AG	220,000	$9,757	1.2%	$47.34	+10.6%	NAMEN AKT	H17182108
—	CONSTELLATION PHARMCETICLS I	1,314,743	$8,848	1.1%	$6.73	—	COM	210373106
OSUR	ORASURE TECHNOLOGIES INC	525,000	$8,111	1.0%	$17.66	-7.2%	COM	68554V108
—	HOMOLOGY MEDICINES INC	350,000	$8,001	1.0%	$21.76	—	COM	438083107
—	CLOVIS ONCOLOGY INC	235,000	$6,902	0.8%	$69.25	—	COM	189464100
SRPT	SAREPTA THERAPEUTICS INC	40,000	$6,460	0.8%	$136.70	0.0%	COM	803607100
CDNA	CAREDX INC	200,000	$5,770	0.7%	$11.47	+63.2%	COM	14167L103
NEOG	NEOGEN CORP	65,000	$4,649	0.6%	$30.13	+41.5%	COM	640491106
—	CELGENE CORP	50,000	$4,475	0.5%	—	—	Call	151020104
GILD	GILEAD SCIENCES INC	50,000	$3,861	0.5%	—	—	Call	375558103
CTMX	CYTOMX THERAPEUTICS INC	207,500	$3,839	0.5%	$17.02	+33.9%	COM	23284F105
—	NEON THERAPEUTICS INC	338,345	$2,889	0.4%	$12.60	—	COM	64050Y100
—	JOUNCE THERAPEUTICS INC	375,000	$2,438	0.3%	$18.19	—	COM	481116101