Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q4 2018 (← Previous) (Next →)

Filing Date: Feb 13, 2019

Total Value ($000): $584,510 (100.0% shares, 0.0% debt)

Holdings (31)

— LOXO ONCOLOGY INC 8.6%

Value ($000) $50,425 Shares 360,000 Est. Cost $28.44 Unrealized —

— MYOKARDIA INC 6.6%

Value ($000) $38,599 Shares 790,000 Est. Cost $30.98 Unrealized —

— BLUEPRINT MEDICINES CORP 5.9%

Value ($000) $34,502 Shares 640,000 Est. Cost $53.83 Unrealized —

CDXS CODEXIS INC 5.8%

Value ($000) $33,818 Shares 2,025,000 Est. Cost $5.90 Unrealized +192.3%

— SPARK THERAPEUTICS INC 5.6%

Value ($000) $32,878 Shares 840,000 Est. Cost $53.83 Unrealized —

— BLUEBIRD BIO INC 5.6%

Value ($000) $32,736 Shares 330,000 Est. Cost $124.02 Unrealized —

FATE FATE THERAPEUTICS INC 5.6%

Value ($000) $32,717 Shares 2,550,000 Est. Cost $4.33 Unrealized +222.1%

— SAGE THERAPEUTICS INC 5.1%

Value ($000) $29,886 Shares 312,000 Est. Cost $70.16 Unrealized —

BLFS BIOLIFE SOLUTIONS INC 5.0%

Value ($000) $29,216 Shares 2,428,571 Est. Cost $15.38 Unrealized -22.4%

— INVITAE CORP 4.5%

Value ($000) $26,544 Shares 2,400,000 Est. Cost $16.73 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 4.4%

Value ($000) $25,883 Shares 355,000 Est. Cost $83.48 Unrealized -7.9%

AGIO AGIOS PHARMACEUTICALS INC 3.5%

Value ($000) $20,519 Shares 445,000 Est. Cost $66.22 Unrealized -6.8%

— GENMARK DIAGNOSTICS INC 3.2%

Value ($000) $18,541 Shares 3,815,000 Est. Cost $6.69 Unrealized —

— AUDENTES THERAPEUTICS INC 3.1%

Value ($000) $18,335 Shares 860,000 Est. Cost $23.89 Unrealized —

ILMN ILLUMINA INC 3.1%

Value ($000) $17,996 Shares 60,000 Est. Cost $196.93 Unrealized +57.3%

SRPT SAREPTA THERAPEUTICS INC 2.8%

Value ($000) $16,370 Shares 150,000 Est. Cost $128.17 Unrealized -2.4%

— MAGENTA THERAPEUTICS INC 2.6%

Value ($000) $15,067 Shares 2,643,317 Est. Cost $12.22 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 2.5%

Value ($000) $14,368 Shares 350,000 Est. Cost $32.45 Unrealized —

SGMO SANGAMO THERAPEUTICS INC 2.1%

Value ($000) $12,398 Shares 1,080,000 Est. Cost $8.03 Unrealized +54.7%

— GRITSTONE ONCOLOGY INC 1.9%

Value ($000) $11,133 Shares 720,586 Est. Cost $14.24 Unrealized —

EVH EVOLENT HEALTH INC 1.9%

Value ($000) $10,973 Shares 550,000 Est. Cost $17.59 Unrealized +31.5%

EDIT EDITAS MEDICINE INC 1.9%

Value ($000) $10,920 Shares 480,000 Est. Cost $29.14 Unrealized -6.6%

VYGR VOYAGER THERAPEUTICS INC 1.8%

Value ($000) $10,604 Shares 1,128,075 Est. Cost $14.86 Unrealized —

ONC BEIGENE LTD 1.7%

Value ($000) $9,818 Shares 70,000 Est. Cost $149.93 Unrealized —

— HOMOLOGY MEDICINES INC 1.3%

Value ($000) $7,826 Shares 350,000 Est. Cost $21.76 Unrealized —

— CONSTELLATION PHARMCETICLS I 1.1%

Value ($000) $6,244 Shares 1,556,998 Est. Cost $6.31 Unrealized —

IBB ISHARES TR 1.0%

Value ($000) $5,786 Shares 60,000 Est. Cost $96.43 Unrealized —

CDNA CAREDX INC 0.9%

Value ($000) $5,028 Shares 200,000 Est. Cost $11.47 Unrealized +124.1%

DNLI DENALI THERAPEUTICS INC 0.4%

Value ($000) $2,066 Shares 100,000 Est. Cost $18.14 Unrealized 0.0%

— QUOTIENT LTD 0.3%

Value ($000) $1,989 Shares 325,000 Est. Cost $6.12 Unrealized —

— NEON THERAPEUTICS INC 0.2%

Value ($000) $1,325 Shares 263,344 Est. Cost $12.60 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	LOXO ONCOLOGY INC	360,000	$50,425	8.6%	$28.44	—	COM	548862101
—	MYOKARDIA INC	790,000	$38,599	6.6%	$30.98	—	COM	62857M105
—	BLUEPRINT MEDICINES CORP	640,000	$34,502	5.9%	$53.83	—	COM	09627Y109
CDXS	CODEXIS INC	2,025,000	$33,818	5.8%	$5.90	+192.3%	COM	192005106
—	SPARK THERAPEUTICS INC	840,000	$32,878	5.6%	$53.83	—	COM	84652J103
—	BLUEBIRD BIO INC	330,000	$32,736	5.6%	$124.02	—	COM	09609G100
FATE	FATE THERAPEUTICS INC	2,550,000	$32,717	5.6%	$4.33	+222.1%	COM	31189P102
—	SAGE THERAPEUTICS INC	312,000	$29,886	5.1%	$70.16	—	COM	78667J108
BLFS	BIOLIFE SOLUTIONS INC	2,428,571	$29,216	5.0%	$15.38	-22.4%	COM NEW	09062W204
—	INVITAE CORP	2,400,000	$26,544	4.5%	$16.73	—	COM	46185L103
ALNY	ALNYLAM PHARMACEUTICALS INC	355,000	$25,883	4.4%	$83.48	-7.9%	COM	02043Q107
AGIO	AGIOS PHARMACEUTICALS INC	445,000	$20,519	3.5%	$66.22	-6.8%	COM	00847X104
—	GENMARK DIAGNOSTICS INC	3,815,000	$18,541	3.2%	$6.69	—	COM	372309104
—	AUDENTES THERAPEUTICS INC	860,000	$18,335	3.1%	$23.89	—	COM	05070R104
ILMN	ILLUMINA INC	60,000	$17,996	3.1%	$196.93	+57.3%	COM	452327109
SRPT	SAREPTA THERAPEUTICS INC	150,000	$16,370	2.8%	$128.17	-2.4%	COM	803607100
—	MAGENTA THERAPEUTICS INC	2,643,317	$15,067	2.6%	$12.22	—	COM	55910K108
—	GLOBAL BLOOD THERAPEUTICS IN	350,000	$14,368	2.5%	$32.45	—	COM	37890U108
SGMO	SANGAMO THERAPEUTICS INC	1,080,000	$12,398	2.1%	$8.03	+54.7%	COM	800677106
—	GRITSTONE ONCOLOGY INC	720,586	$11,133	1.9%	$14.24	—	COM	39868T105
EVH	EVOLENT HEALTH INC	550,000	$10,973	1.9%	$17.59	+31.5%	CL A	30050B101
EDIT	EDITAS MEDICINE INC	480,000	$10,920	1.9%	$29.14	-6.6%	COM	28106W103
VYGR	VOYAGER THERAPEUTICS INC	1,128,075	$10,604	1.8%	$14.86	—	COM	92915B106
ONC	BEIGENE LTD	70,000	$9,818	1.7%	$149.93	—	SPONSORED ADR	07725L102
—	HOMOLOGY MEDICINES INC	350,000	$7,826	1.3%	$21.76	—	COM	438083107
—	CONSTELLATION PHARMCETICLS I	1,556,998	$6,244	1.1%	$6.31	—	COM	210373106
IBB	ISHARES TR	60,000	$5,786	1.0%	$96.43	—	NASDAQ BIOTECH	464287556
CDNA	CAREDX INC	200,000	$5,028	0.9%	$11.47	+124.1%	COM	14167L103
DNLI	DENALI THERAPEUTICS INC	100,000	$2,066	0.4%	$18.14	0.0%	COM	24823R105
—	QUOTIENT LTD	325,000	$1,989	0.3%	$6.12	—	SHS	G73268107
—	NEON THERAPEUTICS INC	263,344	$1,325	0.2%	$12.60	—	COM	64050Y100