Casdin Capital, LLC Diversified Active

Location: New York, NY

CIK: 0001534261 · Show all filings

Period: Q4 2018 (← Previous) (Next →)

Filing Date: Feb 13, 2019

Total Value: $585M (100.0% shares, 0.0% debt)

Holdings (31)

— LOXO ONCOLOGY INC 8.6%

Value $50.42M Shares 360,000 Est. Cost $28.44 Unrealized —

— MYOKARDIA INC 6.6%

Value $38.6M Shares 790,000 Est. Cost $30.98 Unrealized —

— BLUEPRINT MEDICINES CORP 5.9%

Value $34.5M Shares 640,000 Est. Cost $53.83 Unrealized —

CDXS CODEXIS INC 5.8%

Value $33.82M Shares 2,025,000 Est. Cost $5.90 Unrealized +192.3%

— SPARK THERAPEUTICS INC 5.6%

Value $32.88M Shares 840,000 Est. Cost $53.83 Unrealized —

— BLUEBIRD BIO INC 5.6%

Value $32.74M Shares 330,000 Est. Cost $124.02 Unrealized —

FATE FATE THERAPEUTICS INC 5.6%

Value $32.72M Shares 2,550,000 Est. Cost $4.33 Unrealized +222.1%

— SAGE THERAPEUTICS INC 5.1%

Value $29.89M Shares 312,000 Est. Cost $70.16 Unrealized —

BLFS BIOLIFE SOLUTIONS INC 5.0%

Value $29.22M Shares 2,428,571 Est. Cost $15.38 Unrealized -22.4%

— INVITAE CORP 4.5%

Value $26.54M Shares 2,400,000 Est. Cost $16.73 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 4.4%

Value $25.88M Shares 355,000 Est. Cost $83.48 Unrealized -7.9%

AGIO AGIOS PHARMACEUTICALS INC 3.5%

Value $20.52M Shares 445,000 Est. Cost $66.22 Unrealized -6.8%

— GENMARK DIAGNOSTICS INC 3.2%

Value $18.54M Shares 3,815,000 Est. Cost $6.69 Unrealized —

— AUDENTES THERAPEUTICS INC 3.1%

Value $18.34M Shares 860,000 Est. Cost $23.89 Unrealized —

ILMN ILLUMINA INC 3.1%

Value $18M Shares 60,000 Est. Cost $196.93 Unrealized +57.3%

SRPT SAREPTA THERAPEUTICS INC 2.8%

Value $16.37M Shares 150,000 Est. Cost $128.17 Unrealized -2.4%

— MAGENTA THERAPEUTICS INC 2.6%

Value $15.07M Shares 2,643,317 Est. Cost $12.22 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 2.5%

Value $14.37M Shares 350,000 Est. Cost $32.45 Unrealized —

SGMO SANGAMO THERAPEUTICS INC 2.1%

Value $12.4M Shares 1,080,000 Est. Cost $8.03 Unrealized +54.7%

— GRITSTONE ONCOLOGY INC 1.9%

Value $11.13M Shares 720,586 Est. Cost $14.24 Unrealized —

EVH EVOLENT HEALTH INC 1.9%

Value $10.97M Shares 550,000 Est. Cost $17.59 Unrealized +31.5%

EDIT EDITAS MEDICINE INC 1.9%

Value $10.92M Shares 480,000 Est. Cost $29.14 Unrealized -6.6%

VYGR VOYAGER THERAPEUTICS INC 1.8%

Value $10.6M Shares 1,128,075 Est. Cost $14.86 Unrealized —

ONC BEIGENE LTD 1.7%

Value $9.818M Shares 70,000 Est. Cost $149.93 Unrealized —

— HOMOLOGY MEDICINES INC 1.3%

Value $7.826M Shares 350,000 Est. Cost $21.76 Unrealized —

— CONSTELLATION PHARMCETICLS I 1.1%

Value $6.244M Shares 1,556,998 Est. Cost $6.31 Unrealized —

IBB ISHARES TR 1.0%

Value $5.786M Shares 60,000 Est. Cost $96.43 Unrealized —

CDNA CAREDX INC 0.9%

Value $5.028M Shares 200,000 Est. Cost $11.47 Unrealized +124.1%

DNLI DENALI THERAPEUTICS INC 0.4%

Value $2.066M Shares 100,000 Est. Cost $18.14 Unrealized 0.0%

— QUOTIENT LTD 0.3%

Value $1.989M Shares 325,000 Est. Cost $6.12 Unrealized —

— NEON THERAPEUTICS INC 0.2%

Value $1.325M Shares 263,344 Est. Cost $12.60 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	LOXO ONCOLOGY INC	360,000	$50.42M	8.6%	$28.44	—	COM	548862101
—	MYOKARDIA INC	790,000	$38.6M	6.6%	$30.98	—	COM	62857M105
—	BLUEPRINT MEDICINES CORP	640,000	$34.5M	5.9%	$53.83	—	COM	09627Y109
CDXS	CODEXIS INC	2,025,000	$33.82M	5.8%	$5.90	+192.3%	COM	192005106
—	SPARK THERAPEUTICS INC	840,000	$32.88M	5.6%	$53.83	—	COM	84652J103
—	BLUEBIRD BIO INC	330,000	$32.74M	5.6%	$124.02	—	COM	09609G100
FATE	FATE THERAPEUTICS INC	2,550,000	$32.72M	5.6%	$4.33	+222.1%	COM	31189P102
—	SAGE THERAPEUTICS INC	312,000	$29.89M	5.1%	$70.16	—	COM	78667J108
BLFS	BIOLIFE SOLUTIONS INC	2,428,571	$29.22M	5.0%	$15.38	-22.4%	COM NEW	09062W204
—	INVITAE CORP	2,400,000	$26.54M	4.5%	$16.73	—	COM	46185L103
ALNY	ALNYLAM PHARMACEUTICALS INC	355,000	$25.88M	4.4%	$83.48	-7.9%	COM	02043Q107
AGIO	AGIOS PHARMACEUTICALS INC	445,000	$20.52M	3.5%	$66.22	-6.8%	COM	00847X104
—	GENMARK DIAGNOSTICS INC	3,815,000	$18.54M	3.2%	$6.69	—	COM	372309104
—	AUDENTES THERAPEUTICS INC	860,000	$18.34M	3.1%	$23.89	—	COM	05070R104
ILMN	ILLUMINA INC	60,000	$18M	3.1%	$196.93	+57.3%	COM	452327109
SRPT	SAREPTA THERAPEUTICS INC	150,000	$16.37M	2.8%	$128.17	-2.4%	COM	803607100
—	MAGENTA THERAPEUTICS INC	2,643,317	$15.07M	2.6%	$12.22	—	COM	55910K108
—	GLOBAL BLOOD THERAPEUTICS IN	350,000	$14.37M	2.5%	$32.45	—	COM	37890U108
SGMO	SANGAMO THERAPEUTICS INC	1,080,000	$12.4M	2.1%	$8.03	+54.7%	COM	800677106
—	GRITSTONE ONCOLOGY INC	720,586	$11.13M	1.9%	$14.24	—	COM	39868T105
EVH	EVOLENT HEALTH INC	550,000	$10.97M	1.9%	$17.59	+31.5%	CL A	30050B101
EDIT	EDITAS MEDICINE INC	480,000	$10.92M	1.9%	$29.14	-6.6%	COM	28106W103
VYGR	VOYAGER THERAPEUTICS INC	1,128,075	$10.6M	1.8%	$14.86	—	COM	92915B106
ONC	BEIGENE LTD	70,000	$9.818M	1.7%	$149.93	—	SPONSORED ADR	07725L102
—	HOMOLOGY MEDICINES INC	350,000	$7.826M	1.3%	$21.76	—	COM	438083107
—	CONSTELLATION PHARMCETICLS I	1,556,998	$6.244M	1.1%	$6.31	—	COM	210373106
IBB	ISHARES TR	60,000	$5.786M	1.0%	$96.43	—	NASDAQ BIOTECH	464287556
CDNA	CAREDX INC	200,000	$5.028M	0.9%	$11.47	+124.1%	COM	14167L103
DNLI	DENALI THERAPEUTICS INC	100,000	$2.066M	0.4%	$18.14	0.0%	COM	24823R105
—	QUOTIENT LTD	325,000	$1.989M	0.3%	$6.12	—	SHS	G73268107
—	NEON THERAPEUTICS INC	263,344	$1.325M	0.2%	$12.60	—	COM	64050Y100