Sio Capital Management, LLC Hedge Fund

Location: New York, NY

CIK: 0001482416 · Show all filings

Period: Q4 2015 (← Previous) (Next →)

Filing Date: Feb 16, 2016

Total Value: $226M (100.0% shares, 0.0% debt)

Holdings (42)

— QUOTIENT ORD 12.7%

Value $28.63M Shares 1,789,156 Est. Cost $15.74 Unrealized —

— DYAX ORD 11.5%

Value $25.87M Shares 687,600 Est. Cost $37.62 Unrealized —

SNY SANOFI ORD 6.8%

Value $15.44M Shares 361,962 Est. Cost $44.40 Unrealized —

— NEOS THERAPEUTICS ORD 5.0%

Value $11.19M Shares 781,514 Est. Cost $20.03 Unrealized —

MCK MCKESSON ORD 4.9%

Value $11.04M Shares 56,000 Est. Cost $174.49 Unrealized 0.0%

— ADVANCED ACLRTR APLCTN ADR REP ORD 4.0%

Value $9.127M Shares 291,877 Est. Cost $31.27 Unrealized —

— IGNYTA ORD 3.8%

Value $8.638M Shares 644,617 Est. Cost $13.61 Unrealized —

— VITAMIN SHOPPE ORD 3.5%

Value $7.848M Shares 240,000 Est. Cost $32.70 Unrealized —

— CIGNA ORD 3.2%

Value $7.149M Shares 48,855 Est. Cost $145.54 Unrealized —

— ADAMIS PHARMACEUTICALS ORD 3.2%

Value $7.121M Shares 1,318,630 Est. Cost $5.96 Unrealized —

— CTI BIOPHARMA ORD 2.9%

Value $6.509M Shares 5,292,262 Est. Cost $1.23 Unrealized —

— ANTHERA PHARMACEUTICALS ORD 2.8%

Value $6.396M Shares 1,378,443 Est. Cost $5.98 Unrealized —

ABBV ABBVIE ORD 2.7%

Value $6.15M Shares 103,809 Est. Cost $40.92 Unrealized -7.2%

— ST JUDE MEDICAL ORD 2.5%

Value $5.732M Shares 92,800 Est. Cost $61.77 Unrealized —

— PFENEX ORD 2.5%

Value $5.537M Shares 447,262 Est. Cost $10.12 Unrealized —

— AETNA ORD 2.4%

Value $5.482M Shares 50,700 Est. Cost $108.13 Unrealized —

ZBH ZIMMER BIOMET HOLDINGS ORD 2.4%

Value $5.428M Shares 52,912 Est. Cost $90.02 Unrealized 0.0%

ASND ASCENDIS PHARMA ADR REP ORD 2.3%

Value $5.217M Shares 284,785 Est. Cost $17.72 Unrealized —

UNH UNITEDHEALTH GRP ORD 1.8%

Value $4.176M Shares 35,500 Est. Cost $101.20 Unrealized -1.9%

BMY BRISTOL MYERS SQUIBB ORD 1.6%

Value $3.705M Shares 53,862 Est. Cost $44.54 Unrealized +4.8%

— NATUS MEDICAL ORD 1.5%

Value $3.388M Shares 70,500 Est. Cost $41.96 Unrealized —

— FOAMIX PHARMACEUTICALS ORD 1.5%

Value $3.374M Shares 415,972 Est. Cost $8.61 Unrealized —

— ADAMAS PHARMACEUTICALS ORD 1.5%

Value $3.321M Shares 117,257 Est. Cost $18.27 Unrealized —

ADUS ADDUS HOMECARE ORD 1.3%

Value $2.922M Shares 125,526 Est. Cost $25.18 Unrealized 0.0%

MRK MERCK & CO ORD 1.3%

Value $2.872M Shares 54,375 Est. Cost $36.77 Unrealized 0.0%

TEVA TEVA PHARMA IND ADR REP 1 ORD 1.2%

Value $2.797M Shares 42,610 Est. Cost $65.64 Unrealized —

MDT MEDTRONIC ORD 1.2%

Value $2.692M Shares 35,000 Est. Cost $57.87 Unrealized +1.2%

HRTX HERON THERAPEUTICS ORD 1.2%

Value $2.664M Shares 99,772 Est. Cost $26.74 Unrealized 0.0%

— BIOTELEMETRY ORD 1.0%

Value $2.24M Shares 191,755 Est. Cost $11.68 Unrealized —

SRPT SAREPTA THERAPEUTICS ORD 0.9%

Value $1.929M Shares 50,000 Est. Cost — Unrealized —

— THRESHOLD PHARMACEUTICALS ORD 0.9%

Value $1.922M Shares 4,003,992 Est. Cost $0.48 Unrealized —

— FORWARD PHARMA ADR REP 1 ORD 0.8%

Value $1.9M Shares 100,000 Est. Cost $19.00 Unrealized —

— FLAMEL TECHNOLOGIES ADR REP 1 ORD 0.7%

Value $1.514M Shares 124,017 Est. Cost $21.19 Unrealized —

— RITE AID ORD 0.6%

Value $1.349M Shares 172,114 Est. Cost $7.84 Unrealized —

LNTH LANTHEUS HOLDINGS ORD 0.5%

Value $1.229M Shares 363,748 Est. Cost $3.60 Unrealized 0.0%

— SCYNEXIS ORD 0.4%

Value $1.007M Shares 162,175 Est. Cost $9.91 Unrealized —

— AGILE THERAPEUTICS ORD 0.3%

Value $725K Shares 74,267 Est. Cost $6.27 Unrealized —

— ARATANA THERAPEUTICS ORD 0.2%

Value $543K Shares 97,376 Est. Cost $16.31 Unrealized —

OASMY OASMIA PHARMACEUTICAL ORD 0.2%

Value $445K Shares 123,000 Est. Cost $3.62 Unrealized —

— RELYPSA ORD 0.1%

Value $283K Shares 10,000 Est. Cost $28.30 Unrealized —

— INSPIREMD ORD 0.1%

Value $191K Shares 216,645 Est. Cost $0.16 Unrealized —

— IMMUNE PHARMACEUTICALS ORD 0.1%

Value $144K Shares 197,655 Est. Cost $1.18 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	QUOTIENT ORD	1,789,156	$28.63M	12.7%	$15.74	—	COMMON STOCK	G73268107
—	DYAX ORD	687,600	$25.87M	11.5%	$37.62	—	COMMON STOCK	26746E103
SNY	SANOFI ORD	361,962	$15.44M	6.8%	$44.40	—	ADR	80105N105
—	NEOS THERAPEUTICS ORD	781,514	$11.19M	5.0%	$20.03	—	COMMON STOCK	64052L106
MCK	MCKESSON ORD	56,000	$11.04M	4.9%	$174.49	0.0%	COMMON STOCK	58155Q103
—	ADVANCED ACLRTR APLCTN ADR REP ORD	291,877	$9.127M	4.0%	$31.27	—	ADR	00790T100
—	IGNYTA ORD	644,617	$8.638M	3.8%	$13.61	—	COMMON STOCK	451731103
—	VITAMIN SHOPPE ORD	240,000	$7.848M	3.5%	$32.70	—	COMMON STOCK	92849E101
—	CIGNA ORD	48,855	$7.149M	3.2%	$145.54	—	COMMON STOCK	125509109
—	ADAMIS PHARMACEUTICALS ORD	1,318,630	$7.121M	3.2%	$5.96	—	COMMON STOCK	00547W208
—	CTI BIOPHARMA ORD	5,292,262	$6.509M	2.9%	$1.23	—	COMMON STOCK	12648L106
—	ANTHERA PHARMACEUTICALS ORD	1,378,443	$6.396M	2.8%	$5.98	—	COMMON STOCK	03674U201
ABBV	ABBVIE ORD	103,809	$6.15M	2.7%	$40.92	-7.2%	COMMON STOCK	00287Y109
—	ST JUDE MEDICAL ORD	92,800	$5.732M	2.5%	$61.77	—	COMMON STOCK	790849103
—	PFENEX ORD	447,262	$5.537M	2.5%	$10.12	—	COMMON STOCK	717071104
—	AETNA ORD	50,700	$5.482M	2.4%	$108.13	—	COMMON STOCK	00817Y108
ZBH	ZIMMER BIOMET HOLDINGS ORD	52,912	$5.428M	2.4%	$90.02	0.0%	COMMON STOCK	98956P102
ASND	ASCENDIS PHARMA ADR REP ORD	284,785	$5.217M	2.3%	$17.72	—	ADR	04351P101
UNH	UNITEDHEALTH GRP ORD	35,500	$4.176M	1.8%	$101.20	-1.9%	COMMON STOCK	91324P102
BMY	BRISTOL MYERS SQUIBB ORD	53,862	$3.705M	1.6%	$44.54	+4.8%	COMMON STOCK	110122108
—	NATUS MEDICAL ORD	70,500	$3.388M	1.5%	$41.96	—	COMMON STOCK	639050103
—	FOAMIX PHARMACEUTICALS ORD	415,972	$3.374M	1.5%	$8.61	—	COMMON STOCK	M46135105
—	ADAMAS PHARMACEUTICALS ORD	117,257	$3.321M	1.5%	$18.27	—	COMMON STOCK	00548A106
ADUS	ADDUS HOMECARE ORD	125,526	$2.922M	1.3%	$25.18	0.0%	COMMON STOCK	006739106
MRK	MERCK & CO ORD	54,375	$2.872M	1.3%	$36.77	0.0%	COMMON STOCK	58933Y105
TEVA	TEVA PHARMA IND ADR REP 1 ORD	42,610	$2.797M	1.2%	$65.64	—	ADR	881624209
MDT	MEDTRONIC ORD	35,000	$2.692M	1.2%	$57.87	+1.2%	COMMON STOCK	G5960L103
HRTX	HERON THERAPEUTICS ORD	99,772	$2.664M	1.2%	$26.74	0.0%	COMMON STOCK	427746102
—	BIOTELEMETRY ORD	191,755	$2.24M	1.0%	$11.68	—	COMMON STOCK	090672106
SRPT	SAREPTA THERAPEUTICS ORD	50,000	$1.929M	0.9%	—	—	Put	803607100
—	THRESHOLD PHARMACEUTICALS ORD	4,003,992	$1.922M	0.9%	$0.48	—	COMMON STOCK	885807206
—	FORWARD PHARMA ADR REP 1 ORD	100,000	$1.9M	0.8%	$19.00	—	ADR	34986J105
—	FLAMEL TECHNOLOGIES ADR REP 1 ORD	124,017	$1.514M	0.7%	$21.19	—	ADR	338488109
—	RITE AID ORD	172,114	$1.349M	0.6%	$7.84	—	COMMON STOCK	767754104
LNTH	LANTHEUS HOLDINGS ORD	363,748	$1.229M	0.5%	$3.60	0.0%	COMMON STOCK	516544103
—	SCYNEXIS ORD	162,175	$1.007M	0.4%	$9.91	—	COMMON STOCK	811292101
—	AGILE THERAPEUTICS ORD	74,267	$725K	0.3%	$6.27	—	COMMON STOCK	00847L100
—	ARATANA THERAPEUTICS ORD	97,376	$543K	0.2%	$16.31	—	COMMON STOCK	03874P101
OASMY	OASMIA PHARMACEUTICAL ORD	123,000	$445K	0.2%	$3.62	—	ADR	67421W109
—	RELYPSA ORD	10,000	$283K	0.1%	$28.30	—	COMMON STOCK	759531106
—	INSPIREMD ORD	216,645	$191K	0.1%	$0.16	—	COMMON STOCK	45779A507
—	IMMUNE PHARMACEUTICALS ORD	197,655	$144K	0.1%	$1.18	—	COMMON STOCK	45254C101