Sio Capital Management, LLC Hedge Fund

Location: New York, NY

CIK: 0001482416 · Show all filings

Period: Q4 2022 (← Previous) (Next →)

Filing Date: Feb 13, 2023

Total Value: $270M (100.0% shares, 0.0% debt)

Holdings (46)

— PROMETHEUS BIOSCIENCES INC 23.4%
Value $63.16M Shares 574,200 Share Price $110.00 Est. Cost/Share — Unrealized @ Report Date —
— MEDICUS SCIENCES ACQUISITION 8.7%
Value $23.39M Shares 2,323,000 Share Price $10.07 Est. Cost/Share $9.72 Unrealized @ Report Date —
BCYC BICYCLE THERAPEUTICS PLC 7.5%
Value $20.23M Shares 683,425 Share Price $29.60 Est. Cost/Share $20.16 Unrealized @ Report Date —
CI CIGNA CORP 6.4%
Value $17.43M Shares 52,611 Share Price $331.34 * Est. Cost/Share $187.09 Unrealized @ Report Date +59.7%
OGN ORGANON & CO 6.1%
Value $16.42M Shares 587,836 Share Price $27.93 * Est. Cost/Share $29.18 Unrealized @ Report Date -24.7%
UTHR UNITED THERAPEUTICS CORP 5.7%
Value $15.28M Shares 54,959 Share Price $278.09 * Est. Cost/Share $165.91 Unrealized @ Report Date +52.2%
DGX QUEST DIAGNOSTICS INC 5.3%
Value $14.39M Shares 92,000 Share Price $156.44 Est. Cost/Share — Unrealized @ Report Date —
COR AMERISOURCEBERGEN CORP 5.2%
Value $13.99M Shares 84,399 Share Price $165.71 * Est. Cost/Share $135.64 Unrealized @ Report Date +13.1%
MDT MEDTRONIC PLC 3.7%
Value $9.948M Shares 128,000 Share Price $77.72 * Est. Cost/Share $73.46 Unrealized @ Report Date 0.0%
STAA STAAR SURGICAL CO 2.8%
Value $7.627M Shares 157,129 Share Price $48.54 * Est. Cost/Share $62.72 Unrealized @ Report Date 0.0%
ICLR ICON PLC 2.4%
Value $6.601M Shares 33,983 Share Price $194.25 * Est. Cost/Share $198.26 Unrealized @ Report Date 0.0%
INGN INOGEN INC 2.1%
Value $5.651M Shares 286,692 Share Price $19.71 * Est. Cost/Share $31.10 Unrealized @ Report Date -30.8%
AVTR AVANTOR INC 1.9%
Value $5.272M Shares 250,000 Share Price $21.09 Est. Cost/Share $20.70 Unrealized @ Report Date 0.0%
— HESKA CORP 1.9%
Value $5.241M Shares 84,309 Share Price $62.16 Est. Cost/Share $62.16 Unrealized @ Report Date —
PTGX PROTAGONIST THERAPEUTICS INC 1.8%
Value $4.742M Shares 434,635 Share Price $10.91 * Est. Cost/Share $8.44 Unrealized @ Report Date 0.0%
NVAX NOVAVAX INC 1.3%
Value $3.495M Shares 340,000 Share Price $10.28 * Est. Cost/Share $17.65 Unrealized @ Report Date 0.0%
— CYMABAY THERAPEUTICS INC 1.3%
Value $3.484M Shares 555,610 Share Price $6.27 Est. Cost/Share $3.37 Unrealized @ Report Date —
PHVS PHARVARIS NV 1.2%
Value $3.206M Shares 285,000 Share Price $11.25 * Est. Cost/Share $5.25 Unrealized @ Report Date 0.0%
— MERRIMACK PHARMACEUTICALS INC 1.1%
Value $2.865M Shares 250,000 Share Price $11.46 Est. Cost/Share $11.46 Unrealized @ Report Date —
— REATA PHARMACEUTICALS INC 0.9%
Value $2.545M Shares 67,000 Share Price $37.99 Est. Cost/Share — Unrealized @ Report Date —
— HEALTH SCIENCES ACQUISITIONS CORP 2 0.9%
Value $2.495M Shares 250,000 Share Price $9.98 Est. Cost/Share $11.00 Unrealized @ Report Date —
— EUCRATES BIOMEDICAL ACQUISITION CORP. 0.9%
Value $2.482M Shares 248,674 Share Price $9.98 Est. Cost/Share $10.66 Unrealized @ Report Date —
— CTI BIOPHARMA CORP 0.7%
Value $1.983M Shares 330,000 Share Price $6.01 Est. Cost/Share $6.01 Unrealized @ Report Date —
— IVERIC BIO INC 0.7%
Value $1.85M Shares 86,400 Share Price $21.41 Est. Cost/Share — Unrealized @ Report Date —
— X4 PHARMACEUTICALS INC 0.7%
Value $1.813M Shares 1,825,963 Share Price $0.99 Est. Cost/Share $2.60 Unrealized @ Report Date —
MODD MODULAR MEDICAL INC 0.5%
Value $1.379M Shares 689,352 Share Price $2.00 * Est. Cost/Share $4.31 Unrealized @ Report Date -30.1%
— MERUS NV 0.5%
Value $1.361M Shares 87,953 Share Price $15.47 Est. Cost/Share $31.80 Unrealized @ Report Date —
— AEGLEA BIO THERAPEUTICS INC 0.5%
Value $1.352M Shares 3,004,959 Share Price $0.45 Est. Cost/Share $1.46 Unrealized @ Report Date —
SVRA SAVARA INC 0.5%
Value $1.343M Shares 866,448 Share Price $1.55 * Est. Cost/Share $1.21 Unrealized @ Report Date +13.1%
IDYA IDEAYA BIOSCIENCES INC 0.5%
Value $1.272M Shares 70,000 Share Price $18.17 * Est. Cost/Share $12.99 Unrealized @ Report Date +29.5%
TYRA TYRA BIOSCIENCES INC 0.4%
Value $1.156M Shares 152,159 Share Price $7.60 * Est. Cost/Share $10.81 Unrealized @ Report Date -34.6%
— MOLECULIN BIOTECH INC 0.4%
Value $1.099M Shares 1,036,853 Share Price $1.06 Est. Cost/Share $4.03 Unrealized @ Report Date —
VNDA VANDA PHARMACEUTICALS INC 0.4%
Value $1.007M Shares 136,325 Share Price $7.39 * Est. Cost/Share $11.29 Unrealized @ Report Date -13.7%
RLMD RELMADA THERAPEUTICS INC 0.3%
Value $822K Shares 235,600 Share Price $3.49 * Est. Cost/Share $8.78 Unrealized @ Report Date 0.0%
RLMD RELMADA THERAPEUTICS INC 0.3%
Value $822K Shares 235,500 Share Price $3.49 * Est. Cost/Share $8.78 Unrealized @ Report Date 0.0%
— FUSION PHARMACEUTICALS INC 0.3%
Value $820K Shares 260,448 Share Price $3.15 Est. Cost/Share $11.22 Unrealized @ Report Date —
— CONNECT BIOPHARMA HOLDINGS LTD 0.2%
Value $519K Shares 597,678 Share Price $0.87 Est. Cost/Share $3.02 Unrealized @ Report Date —
— SIENTRA INC 0.2%
Value $517K Shares 2,550,000 Share Price $0.20 Est. Cost/Share $0.20 Unrealized @ Report Date —
— ASLAN PHARMACEUTICALS LTD 0.2%
Value $457K Shares 1,270,758 Share Price $0.36 Est. Cost/Share $1.92 Unrealized @ Report Date —
— ELEVATION ONCOLOGY INC 0.1%
Value $342K Shares 359,731 Share Price $0.95 Est. Cost/Share $4.95 Unrealized @ Report Date —
— NEXTCURE INC 0.1%
Value $183K Shares 130,000 Share Price $1.41 Est. Cost/Share $6.00 Unrealized @ Report Date —
— CAREMAX INC 0.0%
Value $119K Shares 43,549 Share Price $2.73 Est. Cost/Share $8.24 Unrealized @ Report Date —
— VINCERX PHARMA INC 0.0%
Value $104K Shares 102,049 Share Price $1.02 Est. Cost/Share $18.89 Unrealized @ Report Date —
NYXH NYXOAH SA 0.0%
Value $80,389 Shares 16,110 Share Price $4.99 * Est. Cost/Share $31.50 Unrealized @ Report Date -81.9%
HUMA HUMACYTE INC 0.0%
Value $20,314 Shares 49,998 Share Price $0.41 * Est. Cost/Share $3.04 Unrealized @ Report Date 0.0%
— NEOLEUKIN THERAPEUTICS INC 0.0%
Value $19,501 Shares 38,312 Share Price $0.51 Est. Cost/Share $12.32 Unrealized @ Report Date —