Sio Capital Management, LLC Hedge Fund

Location: New York, NY

CIK: 0001482416 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 12, 2023

Total Value: $202M (100.0% shares, 0.0% debt)

Holdings (44)

CNC CENTENE CORP DEL 13.5%

Value $27.36M Shares 432,834 Est. Cost $70.99 Unrealized 0.0%

CI CIGNA GROUP 11.0%

Value $22.28M Shares 87,175 Est. Cost $222.41 Unrealized +24.2%

BCYC BICYCLE THERAPEUTICS PLC 10.2%

Value $20.58M Shares 967,347 Est. Cost $20.48 Unrealized —

COR AMERISOURCEBERGEN CORP 10.1%

Value $20.52M Shares 128,164 Est. Cost $142.11 Unrealized +8.8%

UTHR UNITED THERAPEUTICS CORP 8.3%

Value $16.8M Shares 75,003 Est. Cost $187.46 Unrealized +31.5%

GEHC GE HEALTHCARE TECHNOLOGIES INC 8.0%

Value $16.15M Shares 196,887 Est. Cost $71.08 Unrealized 0.0%

OGN ORGANON & CO 5.5%

Value $11.09M Shares 471,553 Est. Cost $29.18 Unrealized -20.3%

MDT MEDTRONIC PLC 3.3%

Value $6.773M Shares 84,012 Est. Cost $73.46 Unrealized +1.4%

AVTR AVANTOR INC 3.0%

Value $5.985M Shares 283,136 Est. Cost $20.95 Unrealized +8.8%

ADCT ADC THERAPEUTICS SA 2.1%

Value $4.213M Shares 2,160,632 Est. Cost $3.69 Unrealized 0.0%

VKTX VIKING THERAPEUTICS INC 2.1%

Value $4.162M Shares 250,000 Est. Cost $10.33 Unrealized 0.0%

— AXONICS INC 1.9%

Value $3.865M Shares 70,841 Est. Cost $54.56 Unrealized —

GMED GLOBUS MEDICAL INC 1.9%

Value $3.823M Shares 67,500 Est. Cost $64.12 Unrealized 0.0%

RLAY RELAY THERAPEUTICS INC 1.9%

Value $3.788M Shares 230,013 Est. Cost $17.93 Unrealized 0.0%

— MERRIMACK PHARMACEUTICALS INC 1.7%

Value $3.353M Shares 272,843 Est. Cost $11.53 Unrealized —

RVMD REVOLUTION MEDICINES INC 1.3%

Value $2.728M Shares 125,957 Est. Cost $24.62 Unrealized 0.0%

— EUCRATES BIOMEDICAL ACQUISITION CORP. 1.3%

Value $2.579M Shares 248,674 Est. Cost $10.66 Unrealized —

— REPARE THERAPEUTICS INC 1.1%

Value $2.249M Shares 228,538 Est. Cost $9.84 Unrealized —

— CTI BIOPHARMA CORP 1.1%

Value $2.21M Shares 526,239 Est. Cost $5.34 Unrealized —

SVRA SAVARA INC 0.9%

Value $1.849M Shares 948,457 Est. Cost $1.30 Unrealized +72.9%

PHVS PHARVARIS NV 0.9%

Value $1.84M Shares 228,385 Est. Cost $5.25 Unrealized +67.5%

— HESKA CORP 0.8%

Value $1.703M Shares 17,450 Est. Cost $62.16 Unrealized —

— ELEVATION ONCOLOGY INC 0.8%

Value $1.666M Shares 876,611 Est. Cost $3.15 Unrealized —

INGN INOGEN INC 0.7%

Value $1.517M Shares 121,535 Est. Cost $31.10 Unrealized -38.4%

NYXH NYXOAH SA 0.7%

Value $1.411M Shares 188,875 Est. Cost $7.81 Unrealized -28.3%

CNTA CENTESSA PHARMACEUTICALS PLC 0.7%

Value $1.339M Shares 347,869 Est. Cost $3.85 Unrealized —

APRE APREA THERAPEUTICS INC 0.6%

Value $1.243M Shares 280,000 Est. Cost $7.27 Unrealized 0.0%

CRBP CORBUS PHARMACEUTICALS HOLDINGS 0.5%

Value $1.091M Shares 150,000 Est. Cost $4.38 Unrealized 0.0%

MODD MODULAR MEDICAL INC 0.5%

Value $1M Shares 689,352 Est. Cost $4.31 Unrealized -47.2%

— MOLECULIN BIOTECH INC 0.5%

Value $971K Shares 1,010,956 Est. Cost $4.03 Unrealized —

IDYA IDEAYA BIOSCIENCES INC 0.5%

Value $961K Shares 70,000 Est. Cost $12.99 Unrealized +28.3%

— FUSION PHARMACEUTICALS INC 0.5%

Value $928K Shares 246,036 Est. Cost $11.22 Unrealized —

— AEGLEA BIO THERAPEUTICS INC 0.4%

Value $871K Shares 3,004,959 Est. Cost $1.46 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 0.4%

Value $841K Shares 123,797 Est. Cost $11.29 Unrealized -37.7%

— ASLAN PHARMACEUTICALS LTD 0.4%

Value $732K Shares 254,150 Est. Cost $2.88 Unrealized —

— NEOVASC INC 0.3%

Value $657K Shares 22,537 Est. Cost $29.15 Unrealized —

— SIENTRA INC 0.2%

Value $393K Shares 254,997 Est. Cost $1.54 Unrealized —

— MERUS NV 0.1%

Value $286K Shares 15,564 Est. Cost $31.80 Unrealized —

— NEXTCURE INC 0.1%

Value $192K Shares 130,000 Est. Cost $6.00 Unrealized —

— VINCERX PHARMA INC 0.1%

Value $106K Shares 102,049 Est. Cost $18.89 Unrealized —

— CAREMAX INC 0.0%

Value $82,078 Shares 30,741 Est. Cost $8.24 Unrealized —

RCKTW ROCKET PHARMACEUTICALS INC 0.0%

Value $65,360 Shares 400,000 Est. Cost $0.16 Unrealized —

HUMAW HUMACYTE INC 0.0%

Value $29,936 Shares 49,998 Est. Cost $0.60 Unrealized —

— CAREMAX INC 0.0%

Value $5,668 Shares 12,808 Est. Cost $0.44 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
CNC	CENTENE CORP DEL	432,834	$27.36M	13.5%	$70.99	0.0%	COM	15135B101
CI	CIGNA GROUP	87,175	$22.28M	11.0%	$222.41	+24.2%	COM	125523100
BCYC	BICYCLE THERAPEUTICS PLC	967,347	$20.58M	10.2%	$20.48	—	SPONSORED ADS	088786108
COR	AMERISOURCEBERGEN CORP	128,164	$20.52M	10.1%	$142.11	+8.8%	COM	03073E105
UTHR	UNITED THERAPEUTICS CORP	75,003	$16.8M	8.3%	$187.46	+31.5%	COM	91307C102
GEHC	GE HEALTHCARE TECHNOLOGIES INC	196,887	$16.15M	8.0%	$71.08	0.0%	COMMON STOCK	36266G107
OGN	ORGANON & CO	471,553	$11.09M	5.5%	$29.18	-20.3%	COMMON STOCK	68622V106
MDT	MEDTRONIC PLC	84,012	$6.773M	3.3%	$73.46	+1.4%	SHS	G5960L103
AVTR	AVANTOR INC	283,136	$5.985M	3.0%	$20.95	+8.8%	COM	05352A100
ADCT	ADC THERAPEUTICS SA	2,160,632	$4.213M	2.1%	$3.69	0.0%	SHS	H0036K147
VKTX	VIKING THERAPEUTICS INC	250,000	$4.162M	2.1%	$10.33	0.0%	COM	92686J106
—	AXONICS INC	70,841	$3.865M	1.9%	$54.56	—	COM	05465P101
GMED	GLOBUS MEDICAL INC	67,500	$3.823M	1.9%	$64.12	0.0%	CL A	379577208
RLAY	RELAY THERAPEUTICS INC	230,013	$3.788M	1.9%	$17.93	0.0%	COM	75943R102
—	MERRIMACK PHARMACEUTICALS INC	272,843	$3.353M	1.7%	$11.53	—	COM NEW	590328209
RVMD	REVOLUTION MEDICINES INC	125,957	$2.728M	1.3%	$24.62	0.0%	COM	76155X100
—	EUCRATES BIOMEDICAL ACQUISITION CORP.	248,674	$2.579M	1.3%	$10.66	—	UNIT 10/23/2027	G3141W114
—	REPARE THERAPEUTICS INC	228,538	$2.249M	1.1%	$9.84	—	COM	760273102
—	CTI BIOPHARMA CORP	526,239	$2.21M	1.1%	$5.34	—	COM	12648L601
SVRA	SAVARA INC	948,457	$1.849M	0.9%	$1.30	+72.9%	COM	805111101
PHVS	PHARVARIS NV	228,385	$1.84M	0.9%	$5.25	+67.5%	COM	N69605108
—	HESKA CORP	17,450	$1.703M	0.8%	$62.16	—	COM RESTRC NEW	42805E306
—	ELEVATION ONCOLOGY INC	876,611	$1.666M	0.8%	$3.15	—	COM	28623U101
INGN	INOGEN INC	121,535	$1.517M	0.7%	$31.10	-38.4%	COM	45780L104
NYXH	NYXOAH SA	188,875	$1.411M	0.7%	$7.81	-28.3%	SHS	B6S7WD106
CNTA	CENTESSA PHARMACEUTICALS PLC	347,869	$1.339M	0.7%	$3.85	—	SPONSORED ADS	152309100
APRE	APREA THERAPEUTICS INC	280,000	$1.243M	0.6%	$7.27	0.0%	COM NEW	03836J201
CRBP	CORBUS PHARMACEUTICALS HOLDINGS	150,000	$1.091M	0.5%	$4.38	0.0%	COM NEW	21833P301
MODD	MODULAR MEDICAL INC	689,352	$1M	0.5%	$4.31	-47.2%	COM NEW	60785L207
—	MOLECULIN BIOTECH INC	1,010,956	$971K	0.5%	$4.03	—	COM	60855D200
IDYA	IDEAYA BIOSCIENCES INC	70,000	$961K	0.5%	$12.99	+28.3%	COM	45166A102
—	FUSION PHARMACEUTICALS INC	246,036	$928K	0.5%	$11.22	—	COM	36118A100
—	AEGLEA BIO THERAPEUTICS INC	3,004,959	$871K	0.4%	$1.46	—	COM	00773J103
VNDA	VANDA PHARMACEUTICALS INC	123,797	$841K	0.4%	$11.29	-37.7%	COM	921659108
—	ASLAN PHARMACEUTICALS LTD	254,150	$732K	0.4%	$2.88	—	SPON ADS NEW	04522R200
—	NEOVASC INC	22,537	$657K	0.3%	$29.15	—	COM	64065J403
—	SIENTRA INC	254,997	$393K	0.2%	$1.54	—	COM	82621J204
—	MERUS NV	15,564	$286K	0.1%	$31.80	—	COM	N5749R100
—	NEXTCURE INC	130,000	$192K	0.1%	$6.00	—	COM	65343E108
—	VINCERX PHARMA INC	102,049	$106K	0.1%	$18.89	—	COM NEW	92731L106
—	CAREMAX INC	30,741	$82,078	0.0%	$8.24	—	COM CL A	14171W103
RCKTW	ROCKET PHARMACEUTICALS INC	400,000	$65,360	0.0%	$0.16	—	*W EXP 09/02/2026	77313F114
HUMAW	HUMACYTE INC	49,998	$29,936	0.0%	$0.60	—	*W EXP 08/27/2026	44486Q111
—	CAREMAX INC	12,808	$5,668	0.0%	$0.44	—	*W EXP 06/08/2026	14171W111