Octagon Capital Advisors LP Quant / Systematic

CIK: 0001839435 · Show all filings

Period: Q4 2023 (← Previous) (Next →)

Filing Date: Feb 14, 2024

Total Value ($000): $624,986 (100.0% shares, 0.0% debt)

Holdings (33)

APLS APELLIS PHARMACEUTICALS INC 26.9%

Value ($000) $168,026 Shares 2,806,980 Est. Cost $47.59 Unrealized +6.6%

— CYMABAY THERAPEUTICS INC 10.1%

Value ($000) $63,154 Shares 2,673,750 Est. Cost $7.72 Unrealized —

— VERONA PHARMA PLC 7.5%

Value ($000) $47,096 Shares 2,369,000 Est. Cost $17.59 Unrealized —

INSM INSMED INC 6.4%

Value ($000) $39,791 Shares 1,284,000 Est. Cost $21.76 Unrealized +19.2%

RCUS ARCUS BIOSCIENCES INC 5.7%

Value ($000) $35,679 Shares 1,868,000 Est. Cost $33.27 Unrealized -52.0%

BBIO BRIDGEBIO PHARMA INC 4.6%

Value ($000) $28,534 Shares 706,800 Est. Cost $30.51 Unrealized -1.5%

CLDX CELLDEX THERAPEUTICS INC NEW 4.5%

Value ($000) $28,060 Shares 707,526 Est. Cost $25.60 Unrealized +14.9%

ROIV ROIVANT SCIENCES LTD 4.5%

Value ($000) $28,008 Shares 2,494,000 Est. Cost $8.56 Unrealized +13.9%

— ALPINE IMMUNE SCIENCES INC 3.8%

Value ($000) $23,659 Shares 1,241,300 Est. Cost $11.89 Unrealized —

GPCR STRUCTURE THERAPEUTICS INC 2.7%

Value ($000) $16,875 Shares 414,000 Est. Cost $40.76 Unrealized —

CNTA CENTESSA PHARMACEUTICALS PLC 2.6%

Value ($000) $16,398 Shares 2,060,100 Est. Cost $7.11 Unrealized —

ANTX AN2 THERAPEUTICS INC 2.2%

Value ($000) $13,617 Shares 664,575 Est. Cost $7.89 Unrealized +112.1%

VRDN VIRIDIAN THERAPEUTICS INC 2.2%

Value ($000) $13,504 Shares 620,000 Est. Cost $24.88 Unrealized -36.6%

IMVT IMMUNOVANT INC 1.8%

Value ($000) $11,514 Shares 273,289 Est. Cost $36.80 Unrealized 0.0%

DYN DYNE THERAPEUTICS INC 1.7%

Value ($000) $10,546 Shares 792,945 Est. Cost $12.58 Unrealized -22.4%

CYTK CYTOKINETICS INC 1.5%

Value ($000) $9,685 Shares 116,000 Est. Cost $36.21 Unrealized 0.0%

ANNX ANNEXON INC 1.5%

Value ($000) $9,307 Shares 2,050,000 Est. Cost $4.77 Unrealized -48.1%

— AEROVATE THERAPEUTICS INC 1.5%

Value ($000) $9,135 Shares 403,685 Est. Cost $29.30 Unrealized —

GOSS GOSSAMER BIO INC 1.3%

Value ($000) $8,384 Shares 9,187,883 Est. Cost $2.93 Unrealized -74.8%

— RAPT THERAPEUTICS INC 1.2%

Value ($000) $7,256 Shares 292,000 Est. Cost $24.85 Unrealized —

— GLYCOMIMETICS INC 1.1%

Value ($000) $7,080 Shares 3,000,000 Est. Cost $1.26 Unrealized —

— GRACELL BIOTECHNOLOGIES INC 1.0%

Value ($000) $5,990 Shares 596,611 Est. Cost $10.04 Unrealized —

DNTH DIANTHUS THERAPEUTICS INC 0.9%

Value ($000) $5,762 Shares 554,000 Est. Cost $12.41 Unrealized -11.0%

— RENEO PHARMACEUTICALS INC 0.6%

Value ($000) $3,600 Shares 2,250,000 Est. Cost $6.46 Unrealized —

— JASPER THERAPEUTICS INC 0.6%

Value ($000) $3,525 Shares 4,468,114 Est. Cost $1.81 Unrealized —

— VERU INC 0.4%

Value ($000) $2,736 Shares 3,800,000 Est. Cost $0.72 Unrealized —

ANAB ANAPTYSBIO INC 0.4%

Value ($000) $2,570 Shares 120,000 Est. Cost $17.25 Unrealized 0.0%

— INOZYME PHARMA INC 0.3%

Value ($000) $1,704 Shares 400,000 Est. Cost $4.25 Unrealized —

NUVB NUVATION BIO INC 0.2%

Value ($000) $1,510 Shares 1,000,000 Est. Cost $1.29 Unrealized 0.0%

XLO XILIO THERAPEUTICS INC 0.2%

Value ($000) $982 Shares 1,785,000 Est. Cost $2.77 Unrealized -49.1%

MIRM MIRUM PHARMACEUTICALS INC 0.1%

Value ($000) $738 Shares 25,000 Est. Cost $30.26 Unrealized 0.0%

PHAT PHATHOM PHARMACEUTICALS INC 0.1%

Value ($000) $457 Shares 50,000 Est. Cost $8.62 Unrealized 0.0%

ACRS ACLARIS THERAPEUTICS INC 0.0%

Value ($000) $105 Shares 100,000 Est. Cost $3.05 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
APLS	APELLIS PHARMACEUTICALS INC	2,806,980	$168,026	26.9%	$47.59	+6.6%	COM	03753U106
—	CYMABAY THERAPEUTICS INC	2,673,750	$63,154	10.1%	$7.72	—	COM	23257D103
—	VERONA PHARMA PLC	2,369,000	$47,096	7.5%	$17.59	—	SPONSORED ADS	925050106
INSM	INSMED INC	1,284,000	$39,791	6.4%	$21.76	+19.2%	COM PAR $.01	457669307
RCUS	ARCUS BIOSCIENCES INC	1,868,000	$35,679	5.7%	$33.27	-52.0%	COM	03969F109
BBIO	BRIDGEBIO PHARMA INC	706,800	$28,534	4.6%	$30.51	-1.5%	COM	10806X102
CLDX	CELLDEX THERAPEUTICS INC NEW	707,526	$28,060	4.5%	$25.60	+14.9%	COM NEW	15117B202
ROIV	ROIVANT SCIENCES LTD	2,494,000	$28,008	4.5%	$8.56	+13.9%	SHS	G76279101
—	ALPINE IMMUNE SCIENCES INC	1,241,300	$23,659	3.8%	$11.89	—	COM	02083G100
GPCR	STRUCTURE THERAPEUTICS INC	414,000	$16,875	2.7%	$40.76	—	SPONSORED ADS	86366E106
CNTA	CENTESSA PHARMACEUTICALS PLC	2,060,100	$16,398	2.6%	$7.11	—	SPONSORED ADS	152309100
ANTX	AN2 THERAPEUTICS INC	664,575	$13,617	2.2%	$7.89	+112.1%	COM	037326105
VRDN	VIRIDIAN THERAPEUTICS INC	620,000	$13,504	2.2%	$24.88	-36.6%	COM	92790C104
IMVT	IMMUNOVANT INC	273,289	$11,514	1.8%	$36.80	0.0%	COM	45258J102
DYN	DYNE THERAPEUTICS INC	792,945	$10,546	1.7%	$12.58	-22.4%	COM	26818M108
CYTK	CYTOKINETICS INC	116,000	$9,685	1.5%	$36.21	0.0%	COM NEW	23282W605
ANNX	ANNEXON INC	2,050,000	$9,307	1.5%	$4.77	-48.1%	COM	03589W102
—	AEROVATE THERAPEUTICS INC	403,685	$9,135	1.5%	$29.30	—	COM	008064107
GOSS	GOSSAMER BIO INC	9,187,883	$8,384	1.3%	$2.93	-74.8%	COM	38341P102
—	RAPT THERAPEUTICS INC	292,000	$7,256	1.2%	$24.85	—	COM	75382E109
—	GLYCOMIMETICS INC	3,000,000	$7,080	1.1%	$1.26	—	COM	38000Q102
—	GRACELL BIOTECHNOLOGIES INC	596,611	$5,990	1.0%	$10.04	—	SPONSORED ADS	38406L103
DNTH	DIANTHUS THERAPEUTICS INC	554,000	$5,762	0.9%	$12.41	-11.0%	COM	252828108
—	RENEO PHARMACEUTICALS INC	2,250,000	$3,600	0.6%	$6.46	—	COM	75974E103
—	JASPER THERAPEUTICS INC	4,468,114	$3,525	0.6%	$1.81	—	COM	471871103
—	VERU INC	3,800,000	$2,736	0.4%	$0.72	—	COM	92536C103
ANAB	ANAPTYSBIO INC	120,000	$2,570	0.4%	$17.25	0.0%	COM	032724106
—	INOZYME PHARMA INC	400,000	$1,704	0.3%	$4.25	—	COM	45790W108
NUVB	NUVATION BIO INC	1,000,000	$1,510	0.2%	$1.29	0.0%	COM CL A	67080N101
XLO	XILIO THERAPEUTICS INC	1,785,000	$982	0.2%	$2.77	-49.1%	COM	98422T100
MIRM	MIRUM PHARMACEUTICALS INC	25,000	$738	0.1%	$30.26	0.0%	COM	604749101
PHAT	PHATHOM PHARMACEUTICALS INC	50,000	$457	0.1%	$8.62	0.0%	COM	71722W107
ACRS	ACLARIS THERAPEUTICS INC	100,000	$105	0.0%	$3.05	0.0%	COM	00461U105