Octagon Capital Advisors LP Quant / Systematic

CIK: 0001839435 · Show all filings

Period: Q3 2023 (← Previous) (Next →)

Filing Date: Nov 14, 2023

Total Value ($000): $650,903 (100.0% shares, 0.0% debt)

Holdings (40)

APLS APELLIS PHARMACEUTICALS INC 18.3%

Value ($000) $119,065 Shares 3,130,000 Est. Cost $47.59 Unrealized -7.7%

ROIV ROIVANT SCIENCES LTD 7.8%

Value ($000) $51,007 Shares 4,367,000 Est. Cost $8.56 Unrealized +32.1%

— CYMABAY THERAPEUTICS INC 7.0%

Value ($000) $45,830 Shares 3,073,750 Est. Cost $7.72 Unrealized —

— VERONA PHARMA PLC 5.9%

Value ($000) $38,615 Shares 2,369,000 Est. Cost $17.59 Unrealized —

IMVT IMMUNOVANT INC 5.9%

Value ($000) $38,390 Shares 1,000,000 Est. Cost — Unrealized —

RCUS ARCUS BIOSCIENCES INC 5.4%

Value ($000) $35,326 Shares 1,968,000 Est. Cost $33.27 Unrealized -39.6%

INSM INSMED INC 5.0%

Value ($000) $32,421 Shares 1,284,000 Est. Cost $21.76 Unrealized +5.1%

— MIRATI THERAPEUTICS INC 4.4%

Value ($000) $28,534 Shares 655,051 Est. Cost $52.54 Unrealized —

APLS APELLIS PHARMACEUTICALS INC 3.9%

Value ($000) $25,677 Shares 675,000 Est. Cost $47.59 Unrealized -7.7%

BBIO BRIDGEBIO PHARMA INC 3.9%

Value ($000) $25,622 Shares 971,639 Est. Cost $30.51 Unrealized -7.0%

CLDX CELLDEX THERAPEUTICS INC NEW 3.2%

Value ($000) $20,912 Shares 759,898 Est. Cost $25.60 Unrealized +22.5%

— 89BIO INC 2.9%

Value ($000) $18,824 Shares 1,219,157 Est. Cost $16.51 Unrealized —

— RENEO PHARMACEUTICALS INC 2.7%

Value ($000) $17,361 Shares 2,279,870 Est. Cost $6.46 Unrealized —

VRDN VIRIDIAN THERAPEUTICS INC 2.5%

Value ($000) $16,370 Shares 1,067,143 Est. Cost $24.88 Unrealized -23.3%

APLS APELLIS PHARMACEUTICALS INC 2.3%

Value ($000) $15,216 Shares 400,000 Est. Cost $47.59 Unrealized -7.7%

ANTX AN2 THERAPEUTICS INC 2.1%

Value ($000) $13,951 Shares 867,575 Est. Cost $7.89 Unrealized +43.6%

AMLX AMYLYX PHARMACEUTICALS INC 2.0%

Value ($000) $12,725 Shares 695,000 Est. Cost $21.15 Unrealized 0.0%

TSHA TAYSHA GENE THERAPIES INC 1.3%

Value ($000) $8,778 Shares 2,777,778 Est. Cost $1.87 Unrealized 0.0%

— ALPINE IMMUNE SCIENCES INC 1.3%

Value ($000) $8,588 Shares 750,000 Est. Cost $7.20 Unrealized —

GOSS GOSSAMER BIO INC 1.0%

Value ($000) $6,819 Shares 8,187,883 Est. Cost $3.20 Unrealized -63.9%

— AEROVATE THERAPEUTICS INC 1.0%

Value ($000) $6,749 Shares 497,370 Est. Cost $29.30 Unrealized —

DNTH DIANTHUS THERAPEUTICS INC 1.0%

Value ($000) $6,562 Shares 480,000 Est. Cost $12.62 Unrealized 0.0%

DYN DYNE THERAPEUTICS INC 1.0%

Value ($000) $6,209 Shares 692,945 Est. Cost $12.99 Unrealized -17.1%

PMVP PMV PHARMACEUTICALS INC 0.9%

Value ($000) $5,551 Shares 904,000 Est. Cost $6.03 Unrealized +14.1%

— INOZYME PHARMA INC 0.8%

Value ($000) $5,460 Shares 1,300,000 Est. Cost $4.25 Unrealized —

XLO XILIO THERAPEUTICS INC 0.8%

Value ($000) $4,892 Shares 2,318,500 Est. Cost $2.77 Unrealized -3.9%

ANNX ANNEXON INC 0.7%

Value ($000) $4,838 Shares 2,050,000 Est. Cost $4.77 Unrealized -36.6%

— GLYCOMIMETICS INC 0.7%

Value ($000) $4,500 Shares 3,000,000 Est. Cost $1.26 Unrealized —

VKTX VIKING THERAPEUTICS INC 0.6%

Value ($000) $4,151 Shares 375,000 Est. Cost $4.46 Unrealized +220.4%

GLUE MONTE ROSA THERAPEUTICS INC 0.6%

Value ($000) $3,894 Shares 812,895 Est. Cost $6.44 Unrealized -0.0%

— JASPER THERAPEUTICS INC 0.5%

Value ($000) $3,128 Shares 4,468,114 Est. Cost $1.81 Unrealized —

CNTA CENTESSA PHARMACEUTICALS PLC 0.5%

Value ($000) $3,077 Shares 475,600 Est. Cost $4.28 Unrealized —

VIR VIR BIOTECHNOLOGY INC 0.5%

Value ($000) $3,046 Shares 325,050 Est. Cost $25.11 Unrealized -43.2%

TVTX TRAVERE THERAPEUTICS INC 0.4%

Value ($000) $2,682 Shares 300,000 Est. Cost $21.26 Unrealized -33.6%

LXRX LEXICON PHARMACEUTICALS INC 0.3%

Value ($000) $2,096 Shares 1,923,076 Est. Cost $2.65 Unrealized -33.9%

ORIC ORIC PHARMACEUTICALS INC 0.2%

Value ($000) $1,237 Shares 204,500 Est. Cost $5.68 Unrealized +44.3%

— ITEOS THERAPEUTICS INC 0.2%

Value ($000) $1,117 Shares 102,000 Est. Cost $18.03 Unrealized —

— CYMABAY THERAPEUTICS INC 0.1%

Value ($000) $895 Shares 60,000 Est. Cost $7.72 Unrealized —

— BIONOMICS LIMITED 0.1%

Value ($000) $454 Shares 168,000 Est. Cost $2.70 Unrealized —

— HEPION PHARMACEUTICALS INC 0.1%

Value ($000) $337 Shares 67,500 Est. Cost $10.50 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
APLS	APELLIS PHARMACEUTICALS INC	3,130,000	$119,065	18.3%	$47.59	-7.7%	COM	03753U106
ROIV	ROIVANT SCIENCES LTD	4,367,000	$51,007	7.8%	$8.56	+32.1%	SHS	G76279101
—	CYMABAY THERAPEUTICS INC	3,073,750	$45,830	7.0%	$7.72	—	COM	23257D103
—	VERONA PHARMA PLC	2,369,000	$38,615	5.9%	$17.59	—	SPONSORED ADS	925050106
IMVT	IMMUNOVANT INC	1,000,000	$38,390	5.9%	—	—	Put	45258J102
RCUS	ARCUS BIOSCIENCES INC	1,968,000	$35,326	5.4%	$33.27	-39.6%	COM	03969F109
INSM	INSMED INC	1,284,000	$32,421	5.0%	$21.76	+5.1%	COM PAR $.01	457669307
—	MIRATI THERAPEUTICS INC	655,051	$28,534	4.4%	$52.54	—	COM	60468T105
APLS	APELLIS PHARMACEUTICALS INC	675,000	$25,677	3.9%	$47.59	-7.7%	Put	03753U106
BBIO	BRIDGEBIO PHARMA INC	971,639	$25,622	3.9%	$30.51	-7.0%	COM	10806X102
CLDX	CELLDEX THERAPEUTICS INC NEW	759,898	$20,912	3.2%	$25.60	+22.5%	COM NEW	15117B202
—	89BIO INC	1,219,157	$18,824	2.9%	$16.51	—	COM	282559103
—	RENEO PHARMACEUTICALS INC	2,279,870	$17,361	2.7%	$6.46	—	COM	75974E103
VRDN	VIRIDIAN THERAPEUTICS INC	1,067,143	$16,370	2.5%	$24.88	-23.3%	COM	92790C104
APLS	APELLIS PHARMACEUTICALS INC	400,000	$15,216	2.3%	$47.59	-7.7%	Call	03753U106
ANTX	AN2 THERAPEUTICS INC	867,575	$13,951	2.1%	$7.89	+43.6%	COM	037326105
AMLX	AMYLYX PHARMACEUTICALS INC	695,000	$12,725	2.0%	$21.15	0.0%	COM	03237H101
TSHA	TAYSHA GENE THERAPIES INC	2,777,778	$8,778	1.3%	$1.87	0.0%	COM SHS	877619106
—	ALPINE IMMUNE SCIENCES INC	750,000	$8,588	1.3%	$7.20	—	COM	02083G100
GOSS	GOSSAMER BIO INC	8,187,883	$6,819	1.0%	$3.20	-63.9%	COM	38341P102
—	AEROVATE THERAPEUTICS INC	497,370	$6,749	1.0%	$29.30	—	COM	008064107
DNTH	DIANTHUS THERAPEUTICS INC	480,000	$6,562	1.0%	$12.62	0.0%	COM	252828108
DYN	DYNE THERAPEUTICS INC	692,945	$6,209	1.0%	$12.99	-17.1%	COM	26818M108
PMVP	PMV PHARMACEUTICALS INC	904,000	$5,551	0.9%	$6.03	+14.1%	COM	69353Y103
—	INOZYME PHARMA INC	1,300,000	$5,460	0.8%	$4.25	—	COM	45790W108
XLO	XILIO THERAPEUTICS INC	2,318,500	$4,892	0.8%	$2.77	-3.9%	COM	98422T100
ANNX	ANNEXON INC	2,050,000	$4,838	0.7%	$4.77	-36.6%	COM	03589W102
—	GLYCOMIMETICS INC	3,000,000	$4,500	0.7%	$1.26	—	COM	38000Q102
VKTX	VIKING THERAPEUTICS INC	375,000	$4,151	0.6%	$4.46	+220.4%	COM	92686J106
GLUE	MONTE ROSA THERAPEUTICS INC	812,895	$3,894	0.6%	$6.44	-0.0%	COM	61225M102
—	JASPER THERAPEUTICS INC	4,468,114	$3,128	0.5%	$1.81	—	COM	471871103
CNTA	CENTESSA PHARMACEUTICALS PLC	475,600	$3,077	0.5%	$4.28	—	SPONSORED ADS	152309100
VIR	VIR BIOTECHNOLOGY INC	325,050	$3,046	0.5%	$25.11	-43.2%	COM	92764N102
TVTX	TRAVERE THERAPEUTICS INC	300,000	$2,682	0.4%	$21.26	-33.6%	Call	89422G107
LXRX	LEXICON PHARMACEUTICALS INC	1,923,076	$2,096	0.3%	$2.65	-33.9%	COM NEW	528872302
ORIC	ORIC PHARMACEUTICALS INC	204,500	$1,237	0.2%	$5.68	+44.3%	COM	68622P109
—	ITEOS THERAPEUTICS INC	102,000	$1,117	0.2%	$18.03	—	COM	46565G104
—	CYMABAY THERAPEUTICS INC	60,000	$895	0.1%	$7.72	—	Put	23257D103
—	BIONOMICS LIMITED	168,000	$454	0.1%	$2.70	—	ADS	09063M205
—	HEPION PHARMACEUTICALS INC	67,500	$337	0.1%	$10.50	—	COM NEW	426897302