Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q1 2022 (← Previous) (Next →)

Filing Date: May 16, 2022

Total Value: $461M (100.0% shares, 0.0% debt)

Holdings (42)

SPY SPDR S&P 500 ETF TR 49.0%
Value $226M Shares 500,000 Share Price $451.64 Est. Cost/Share — Unrealized @ Report Date —
XBI SPDR SER TR 5.9%
Value $26.96M Shares 300,000 Share Price $89.88 Est. Cost/Share — Unrealized @ Report Date —
ASND ASCENDIS PHARMA A/S 3.6%
Value $16.43M Shares 140,000 Share Price $117.36 Est. Cost/Share $131.68 Unrealized @ Report Date —
COGT COGENT BIOSCIENCES INC 2.8%
Value $12.73M Shares 1,700,000 Share Price $7.49 * Est. Cost/Share $10.34 Unrealized @ Report Date -32.7%
APLS APELLIS PHARMACEUTICALS INC 2.8%
Value $12.7M Shares 250,000 Share Price $50.81 * Est. Cost/Share $49.72 Unrealized @ Report Date -11.2%
— MERUS N V 2.3%
Value $10.58M Shares 400,000 Share Price $26.44 Est. Cost/Share $29.12 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 2.3%
Value $10.42M Shares 1,100,000 Share Price $9.47 Est. Cost/Share $11.01 Unrealized @ Report Date -14.8%
— SIERRA ONCOLOGY INC 2.3%
Value $10.42M Shares 325,000 Share Price $32.05 Est. Cost/Share $20.61 Unrealized @ Report Date —
CLDX CELLDEX THERAPEUTICS INC NEW 2.2%
Value $10.22M Shares 300,000 Share Price $34.06 * Est. Cost/Share $28.96 Unrealized @ Report Date +10.4%
VRDN VIRIDIAN THERAPEUTICS INC 1.9%
Value $8.624M Shares 466,403 Share Price $18.49 * Est. Cost/Share $18.53 Unrealized @ Report Date +3.7%
— KARUNA THERAPEUTICS INC 1.7%
Value $7.607M Shares 60,000 Share Price $126.78 Est. Cost/Share $126.78 Unrealized @ Report Date —
— IVERIC BIO INC 1.6%
Value $7.574M Shares 450,000 Share Price $16.83 Est. Cost/Share $7.44 Unrealized @ Report Date —
ARVN ARVINAS INC 1.6%
Value $7.403M Shares 110,000 Share Price $67.30 Est. Cost/Share $28.07 Unrealized @ Report Date +142.8%
PCVX VAXCYTE INC 1.6%
Value $7.245M Shares 300,000 Share Price $24.15 * Est. Cost/Share $21.73 Unrealized @ Report Date +0.6%
— KEZAR LIFE SCIENCES INC 1.4%
Value $6.648M Shares 400,000 Share Price $16.62 Est. Cost/Share $16.68 Unrealized @ Report Date —
AXSM AXSOME THERAPEUTICS INC 1.3%
Value $6.209M Shares 150,000 Share Price $41.39 * Est. Cost/Share $31.00 Unrealized @ Report Date 0.0%
— CTI BIOPHARMA CORP 1.3%
Value $6.071M Shares 1,300,000 Share Price $4.67 Est. Cost/Share $2.98 Unrealized @ Report Date —
BCRX BIOCRYST PHARMACEUTICALS INC 1.2%
Value $5.691M Shares 350,000 Share Price $16.26 Est. Cost/Share $16.04 Unrealized @ Report Date 0.0%
— RAPT THERAPEUTICS INC 1.2%
Value $5.498M Shares 250,000 Share Price $21.99 Est. Cost/Share $33.20 Unrealized @ Report Date —
BCYC BICYCLE THERAPEUTICS PLC 1.0%
Value $4.388M Shares 100,000 Share Price $43.88 Est. Cost/Share $43.88 Unrealized @ Report Date —
AXSM AXSOME THERAPEUTICS INC 0.8%
Value $3.911M Shares 94,500 Share Price $41.39 * Est. Cost/Share $31.00 Unrealized @ Report Date 0.0%
SNDX SYNDAX PHARMACEUTICALS INC 0.8%
Value $3.911M Shares 225,000 Share Price $17.38 * Est. Cost/Share $18.21 Unrealized @ Report Date -7.5%
SRPT SAREPTA THERAPEUTICS INC 0.8%
Value $3.906M Shares 50,000 Share Price $78.12 Est. Cost/Share $85.49 Unrealized @ Report Date -10.4%
— VERONA PHARMA PLC 0.8%
Value $3.743M Shares 750,000 Share Price $4.99 Est. Cost/Share $6.53 Unrealized @ Report Date —
ZNTL ZENTALIS PHARMACEUTICALS INC 0.8%
Value $3.691M Shares 80,000 Share Price $46.14 * Est. Cost/Share $61.38 Unrealized @ Report Date -12.1%
DSGN DESIGN THERAPEUTICS INC 0.7%
Value $3.23M Shares 200,000 Share Price $16.15 * Est. Cost/Share $16.57 Unrealized @ Report Date -7.5%
RCKT ROCKET PHARMACEUTICALS INC 0.7%
Value $3.172M Shares 200,000 Share Price $15.86 * Est. Cost/Share $29.94 Unrealized @ Report Date -42.3%
XENE XENON PHARMACEUTICALS INC 0.7%
Value $3.057M Shares 100,000 Share Price $30.57 * Est. Cost/Share $13.60 Unrealized @ Report Date +120.1%
RLMD RELMADA THERAPEUTICS INC 0.6%
Value $2.699M Shares 100,000 Share Price $26.99 * Est. Cost/Share $26.77 Unrealized @ Report Date -22.7%
WHWK AADI BIOSCIENCE INC 0.6%
Value $2.546M Shares 150,000 Share Price $16.97 * Est. Cost/Share $25.11 Unrealized @ Report Date -23.7%
ACRS ACLARIS THERAPEUTICS INC 0.5%
Value $2.155M Shares 125,000 Share Price $17.24 * Est. Cost/Share $6.81 Unrealized @ Report Date +100.4%
TARS TARSUS PHARMACEUTICALS INC 0.4%
Value $2.018M Shares 120,000 Share Price $16.82 * Est. Cost/Share $31.23 Unrealized @ Report Date -40.6%
— 9 METERS BIOPHARMA INC 0.4%
Value $1.948M Shares 3,250,000 Share Price $0.60 Est. Cost/Share $1.25 Unrealized @ Report Date —
CRNX CRINETICS PHARMACEUTICALS IN 0.4%
Value $1.866M Shares 85,000 Share Price $21.95 * Est. Cost/Share $17.57 Unrealized @ Report Date +15.2%
— SATSUMA PHARMACEUTICALS INC 0.4%
Value $1.8M Shares 473,562 Share Price $3.80 Est. Cost/Share $10.24 Unrealized @ Report Date —
— LEAP THERAPEUTICS INC 0.4%
Value $1.739M Shares 993,714 Share Price $1.75 Est. Cost/Share $4.01 Unrealized @ Report Date —
— MIRATI THERAPEUTICS INC 0.4%
Value $1.644M Shares 20,000 Share Price $82.20 Est. Cost/Share $98.34 Unrealized @ Report Date —
— VISTAGEN THERAPEUTICS INC 0.4%
Value $1.631M Shares 1,315,154 Share Price $1.24 Est. Cost/Share $2.02 Unrealized @ Report Date —
— AEGLEA BIOTHERAPEUTICS INC 0.3%
Value $1.579M Shares 686,599 Share Price $2.30 Est. Cost/Share $2.30 Unrealized @ Report Date —
— PARDES BIOSCIENCES INC 0.1%
Value $614K Shares 85,000 Share Price $7.22 Est. Cost/Share $12.61 Unrealized @ Report Date —
LRMR LARIMAR THERAPEUTICS INC 0.1%
Value $405K Shares 100,000 Share Price $4.05 * Est. Cost/Share $11.59 Unrealized @ Report Date -43.5%
PYXS PYXIS ONCOLOGY INC 0.1%
Value $303K Shares 75,000 Share Price $4.04 * Est. Cost/Share $11.45 Unrealized @ Report Date -36.2%