Ghost Tree Capital, LLC Hedge Fund

CIK: 0001595851 · Show all filings

Period: Q3 2022 (← Previous) (Next →)

Filing Date: Nov 14, 2022

Total Value: $356M (100.0% shares, 0.0% debt)

Holdings (44)

XBI SPDR SER TR 11.1%
Value $39.66M Shares 500,000 Share Price $79.32 Est. Cost/Share — Unrealized @ Report Date —
APLS APELLIS PHARMACEUTICALS INC 5.3%
Value $18.78M Shares 275,000 Share Price $68.30 * Est. Cost/Share $51.44 Unrealized @ Report Date +15.0%
RLMD RELMADA THERAPEUTICS INC 5.2%
Value $18.51M Shares 500,000 Share Price $37.02 * Est. Cost/Share $25.40 Unrealized @ Report Date +9.1%
— REATA PHARMACEUTICALS INC 5.1%
Value $18.22M Shares 725,000 Share Price $25.13 Est. Cost/Share $25.13 Unrealized @ Report Date —
RLMD RELMADA THERAPEUTICS INC 4.4%
Value $15.73M Shares 425,000 Share Price $37.02 * Est. Cost/Share $25.40 Unrealized @ Report Date +9.1%
AMLX AMYLYX PHARMACEUTICALS INC 4.3%
Value $15.48M Shares 550,000 Share Price $28.15 * Est. Cost/Share $24.95 Unrealized @ Report Date 0.0%
— DICE THERAPEUTICS INC 4.0%
Value $14.2M Shares 700,000 Share Price $20.28 Est. Cost/Share $15.53 Unrealized @ Report Date —
AMLX AMYLYX PHARMACEUTICALS INC 4.0%
Value $14.07M Shares 500,000 Share Price $28.15 * Est. Cost/Share $24.95 Unrealized @ Report Date 0.0%
AXSM AXSOME THERAPEUTICS INC 3.8%
Value $13.39M Shares 300,000 Share Price $44.62 * Est. Cost/Share $36.01 Unrealized @ Report Date +38.7%
— MIRATI THERAPEUTICS INC 3.4%
Value $12.22M Shares 175,000 Share Price $69.84 Est. Cost/Share $71.70 Unrealized @ Report Date —
SRPT SAREPTA THERAPEUTICS INC 3.4%
Value $12.16M Shares 110,000 Share Price $110.54 * Est. Cost/Share $78.15 Unrealized @ Report Date +29.0%
— CTI BIOPHARMA CORP 3.3%
Value $11.64M Shares 2,000,000 Share Price $5.82 Est. Cost/Share $4.68 Unrealized @ Report Date —
VRDN VIRIDIAN THERAPEUTICS INC 3.1%
Value $10.97M Shares 535,000 Share Price $20.51 * Est. Cost/Share $17.40 Unrealized @ Report Date +3.3%
— REVANCE THERAPEUTICS INC 3.0%
Value $10.53M Shares 390,000 Share Price $27.00 Est. Cost/Share $27.00 Unrealized @ Report Date —
ASND ASCENDIS PHARMA A/S 2.8%
Value $9.81M Shares 95,000 Share Price $103.26 Est. Cost/Share $125.70 Unrealized @ Report Date —
COGT COGENT BIOSCIENCES INC 2.5%
Value $8.952M Shares 600,000 Share Price $14.92 * Est. Cost/Share $10.34 Unrealized @ Report Date +32.5%
PCVX VAXCYTE INC 2.4%
Value $8.64M Shares 360,000 Share Price $24.00 * Est. Cost/Share $22.18 Unrealized @ Report Date +14.3%
— IVERIC BIO INC 2.3%
Value $8.319M Shares 463,700 Share Price $17.94 Est. Cost/Share $7.65 Unrealized @ Report Date —
— SEAGEN INC 1.9%
Value $6.842M Shares 50,000 Share Price $136.84 Est. Cost/Share $176.94 Unrealized @ Report Date —
— KARUNA THERAPEUTICS INC 1.9%
Value $6.748M Shares 30,000 Share Price $224.93 Est. Cost/Share $126.78 Unrealized @ Report Date —
AXSM AXSOME THERAPEUTICS INC 1.9%
Value $6.693M Shares 150,000 Share Price $44.62 * Est. Cost/Share $36.01 Unrealized @ Report Date +38.7%
BCRX BIOCRYST PHARMACEUTICALS INC 1.9%
Value $6.615M Shares 525,000 Share Price $12.60 * Est. Cost/Share $14.83 Unrealized @ Report Date -13.2%
ALT ALTIMMUNE INC 1.6%
Value $5.555M Shares 435,000 Share Price $12.77 * Est. Cost/Share $14.76 Unrealized @ Report Date 0.0%
— TRICIDA INC 1.5%
Value $5.24M Shares 500,000 Share Price $10.48 Est. Cost/Share $10.48 Unrealized @ Report Date —
FOLD AMICUS THERAPEUTICS INC 1.5%
Value $5.22M Shares 500,000 Share Price $10.44 * Est. Cost/Share $11.01 Unrealized @ Report Date +1.2%
— REATA PHARMACEUTICALS INC 1.4%
Value $5.026M Shares 200,000 Share Price $25.13 Est. Cost/Share $25.13 Unrealized @ Report Date —
SNDX SYNDAX PHARMACEUTICALS INC 1.3%
Value $4.806M Shares 200,000 Share Price $24.03 * Est. Cost/Share $18.21 Unrealized @ Report Date +23.2%
— HORIZON THERAPEUTICS PUB L 1.3%
Value $4.642M Shares 75,000 Share Price $61.89 Est. Cost/Share $79.76 Unrealized @ Report Date —
— KEZAR LIFE SCIENCES INC 1.3%
Value $4.52M Shares 525,000 Share Price $8.61 Est. Cost/Share $14.73 Unrealized @ Report Date —
— ASTRIA THERAPEUTICS INC 1.3%
Value $4.52M Shares 500,000 Share Price $9.04 Est. Cost/Share $9.04 Unrealized @ Report Date —
— BLUEPRINT MEDICINES CORP 1.2%
Value $4.283M Shares 65,000 Share Price $65.89 Est. Cost/Share $65.89 Unrealized @ Report Date —
WHWK AADI BIOSCIENCE INC 0.8%
Value $2.826M Shares 200,000 Share Price $14.13 * Est. Cost/Share $22.12 Unrealized @ Report Date -40.6%
— INTRA-CELLULAR THERAPIES INC 0.8%
Value $2.792M Shares 60,000 Share Price $46.53 Est. Cost/Share $46.53 Unrealized @ Report Date —
— AEROVATE THERAPEUTICS INC 0.7%
Value $2.487M Shares 150,000 Share Price $16.58 Est. Cost/Share $16.58 Unrealized @ Report Date —
MLTX MOONLAKE IMMUNOTHERAPEUTICS 0.7%
Value $2.328M Shares 300,000 Share Price $7.76 * Est. Cost/Share $6.29 Unrealized @ Report Date +12.0%
— RAPT THERAPEUTICS INC 0.6%
Value $2.165M Shares 90,000 Share Price $24.06 Est. Cost/Share $33.20 Unrealized @ Report Date —
— TRICIDA INC 0.6%
Value $2.096M Shares 200,000 Share Price $10.48 Est. Cost/Share $10.48 Unrealized @ Report Date —
TARS TARSUS PHARMACEUTICALS INC 0.6%
Value $2.054M Shares 120,000 Share Price $17.12 * Est. Cost/Share $31.23 Unrealized @ Report Date -49.2%
DSGN DESIGN THERAPEUTICS INC 0.5%
Value $1.672M Shares 100,000 Share Price $16.72 * Est. Cost/Share $15.73 Unrealized @ Report Date +26.5%
MDGL MADRIGAL PHARMACEUTICALS INC 0.5%
Value $1.625M Shares 25,000 Share Price $65.00 * Est. Cost/Share $69.48 Unrealized @ Report Date 0.0%
RYTM RHYTHM PHARMACEUTICALS INC 0.4%
Value $1.593M Shares 65,000 Share Price $24.51 * Est. Cost/Share $18.60 Unrealized @ Report Date 0.0%
— IVERIC BIO INC 0.3%
Value $1.1M Shares 61,300 Share Price $17.94 Est. Cost/Share $7.65 Unrealized @ Report Date —
BIIB BIOGEN INC 0.3%
Value $1.001M Shares 3,750 Share Price $266.93 * Est. Cost/Share $212.38 Unrealized @ Report Date 0.0%
— AEGLEA BIOTHERAPEUTICS INC 0.1%
Value $526K Shares 1,000,000 Share Price $0.53 Est. Cost/Share $1.74 Unrealized @ Report Date —