Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q1 2026 (← Previous) (Next →)

Filing Date: May 14, 2026

Total Value: $250M (100.0% shares, 0.0% debt)

Holdings (83)

XBI SPDR SERIES TRUST 20.5%
Value $51.09M Shares 400,000 Share Price $127.73 Est. Cost/Share — Unrealized @ Report Date —
XBI SPDR SERIES TRUST 20.5%
Value $51.09M Shares 400,000 Share Price $127.73 Est. Cost/Share — Unrealized @ Report Date —
VSTM VERASTEM INC 7.0%
Value $17.5M Shares 3,302,300 Share Price $5.30 * Est. Cost/Share $6.16 Unrealized @ Report Date +5.2%
TENX TENAX THERAPEUTICS INC 6.2%
Value $15.59M Shares 975,200 Share Price $15.99 * Est. Cost/Share $13.44 Unrealized @ Report Date +0.4%
ADMA ADMA BIOLOGICS INC 4.1%
Value $10.36M Shares 1,150,000 Share Price $9.01 * Est. Cost/Share $2.26 Unrealized @ Report Date +649.0%
EOLS EVOLUS INC 2.9%
Value $7.23M Shares 1,759,091 Share Price $4.11 * Est. Cost/Share $7.98 Unrealized @ Report Date -38.6%
ADMA ADMA BIOLOGICS INC 2.7%
Value $6.667M Shares 740,000 Share Price $9.01 * Est. Cost/Share $2.26 Unrealized @ Report Date +649.0%
CAMP CAMP4 THERAPEUTICS CORP 2.5%
Value $6.128M Shares 1,389,622 Share Price $4.41 * Est. Cost/Share $4.60 Unrealized @ Report Date +1.5%
NKTR NEKTAR THERAPEUTICS 2.4%
Value $6.116M Shares 85,000 Share Price $71.95 * Est. Cost/Share $20.19 Unrealized @ Report Date +139.4%
TERN TERNS PHARMACEUTICALS INC 2.1%
Value $5.272M Shares 100,000 Share Price $52.72 Est. Cost/Share — Unrealized @ Report Date —
ZVRA ZEVRA THERAPEUTICS INC 1.8%
Value $4.474M Shares 480,000 Share Price $9.32 * Est. Cost/Share $7.20 Unrealized @ Report Date +21.7%
CRBP CORBUS PHARMACEUTICALS HLDGS 1.4%
Value $3.601M Shares 383,462 Share Price $9.39 * Est. Cost/Share $12.34 Unrealized @ Report Date -34.3%
ABEO ABEONA THERAPEUTICS INC 1.3%
Value $3.345M Shares 746,587 Share Price $4.48 * Est. Cost/Share $5.79 Unrealized @ Report Date -10.8%
ESTA ESTABLISHMENT LABS HLDGS INC 1.1%
Value $2.839M Shares 50,000 Share Price $56.78 * Est. Cost/Share $70.34 Unrealized @ Report Date 0.0%
KZIA KAZIA THERAPEUTICS LTD 1.0%
Value $2.568M Shares 345,179 Share Price $7.44 Est. Cost/Share $6.89 Unrealized @ Report Date —
ANTX AN2 THERAPEUTICS INC 1.0%
Value $2.441M Shares 713,845 Share Price $3.42 * Est. Cost/Share $1.18 Unrealized @ Report Date -4.2%
ARE ALEXANDRIA REAL ESTATE EQ IN 0.9%
Value $2.321M Shares 50,000 Share Price $46.42 Est. Cost/Share — Unrealized @ Report Date —
ACAD ACADIA PHARMACEUTICALS INC 0.9%
Value $2.226M Shares 100,000 Share Price $22.26 * Est. Cost/Share $17.77 Unrealized @ Report Date +41.9%
SLGL SOL-GEL TECHNOLOGIES LTD 0.9%
Value $2.201M Shares 27,778 Share Price $79.22 * Est. Cost/Share $66.40 Unrealized @ Report Date 0.0%
XOMA XOMA ROYALTY CORPORATION 0.9%
Value $2.18M Shares 69,500 Share Price $31.37 * Est. Cost/Share $20.48 Unrealized @ Report Date +27.5%
AYTU AYTU BIOPHARMA INC 0.9%
Value $2.163M Shares 792,289 Share Price $2.73 * Est. Cost/Share $1.82 Unrealized @ Report Date +38.7%
CRIS CURIS INC 0.8%
Value $2.039M Shares 3,726,406 Share Price $0.55 * Est. Cost/Share $0.98 Unrealized @ Report Date -0.6%
EOLS EVOLUS INC 0.7%
Value $1.726M Shares 420,000 Share Price $4.11 * Est. Cost/Share $7.98 Unrealized @ Report Date -38.6%
XERS XERIS BIOPHARMA HOLDINGS INC 0.7%
Value $1.624M Shares 280,000 Share Price $5.80 * Est. Cost/Share $7.21 Unrealized @ Report Date 0.0%
TELA TELA BIO INC 0.6%
Value $1.623M Shares 2,617,252 Share Price $0.62 * Est. Cost/Share $3.72 Unrealized @ Report Date -75.1%
IKT INHIBIKASE THERAPEUTICS INC 0.6%
Value $1.608M Shares 957,202 Share Price $1.68 * Est. Cost/Share $1.87 Unrealized @ Report Date -7.4%
CBIO CRESCENT BIOPHARMA INC. 0.6%
Value $1.561M Shares 85,000 Share Price $18.37 * Est. Cost/Share $12.74 Unrealized @ Report Date -13.2%
ACET ADICET BIO INC 0.6%
Value $1.512M Shares 221,955 Share Price $6.81 * Est. Cost/Share $11.05 Unrealized @ Report Date -29.8%
XFOR X4 PHARMACEUTICALS INC 0.6%
Value $1.385M Shares 335,309 Share Price $4.13 * Est. Cost/Share $2.58 Unrealized @ Report Date +41.0%
OKYO OKYO PHARMA LTD 0.5%
Value $1.369M Shares 850,000 Share Price $1.61 * Est. Cost/Share $2.12 Unrealized @ Report Date 0.0%
SIBN SI BONE INC 0.5%
Value $1.263M Shares 100,000 Share Price $12.63 * Est. Cost/Share $16.92 Unrealized @ Report Date 0.0%
MNKD MANNKIND CORP 0.5%
Value $1.225M Shares 500,000 Share Price $2.45 * Est. Cost/Share $4.39 Unrealized @ Report Date +26.9%
HRTX HERON THERAPEUTICS INC 0.4%
Value $1.122M Shares 1,402,191 Share Price $0.80 * Est. Cost/Share $1.49 Unrealized @ Report Date -12.4%
LUNG PULMONX CORP 0.4%
Value $991K Shares 768,288 Share Price $1.29 * Est. Cost/Share $2.22 Unrealized @ Report Date -21.7%
INAB IN8BIO INC 0.4%
Value $982K Shares 663,412 Share Price $1.48 * Est. Cost/Share $2.32 Unrealized @ Report Date -11.4%
NMRA NEUMORA THERAPEUTICS INC. 0.4%
Value $975K Shares 500,000 Share Price $1.95 * Est. Cost/Share $2.46 Unrealized @ Report Date 0.0%
SRZN SURROZEN INC 0.4%
Value $961K Shares 33,005 Share Price $29.13 * Est. Cost/Share $10.69 Unrealized @ Report Date +108.0%
CTMX CYTOMX THERAPEUTICS INC. 0.4%
Value $940K Shares 200,000 Share Price $4.70 * Est. Cost/Share $5.23 Unrealized @ Report Date 0.0%
CTMX CYTOMX THERAPEUTICS INC. 0.4%
Value $940K Shares 200,000 Share Price $4.70 * Est. Cost/Share $5.23 Unrealized @ Report Date 0.0%
DCTH DELCATH SYS INC 0.4%
Value $928K Shares 100,000 Share Price $9.28 * Est. Cost/Share $9.94 Unrealized @ Report Date +0.5%
ARDX ARDELYX INC 0.4%
Value $899K Shares 150,000 Share Price $5.99 Est. Cost/Share — Unrealized @ Report Date —
PMVP PMV PHARMACEUTICALS INC 0.4%
Value $878K Shares 708,102 Share Price $1.24 * Est. Cost/Share $1.40 Unrealized @ Report Date -19.5%
BIOA BIOAGE LABS INC 0.4%
Value $875K Shares 50,000 Share Price $17.49 * Est. Cost/Share $5.81 Unrealized @ Report Date +230.8%
CNTB CONNECT BIOPHARMA HLDGS LTD 0.3%
Value $812K Shares 310,000 Share Price $2.62 * Est. Cost/Share $2.48 Unrealized @ Report Date 0.0%
HRTX HERON THERAPEUTICS INC 0.3%
Value $800K Shares 1,000,000 Share Price $0.80 * Est. Cost/Share $1.49 Unrealized @ Report Date -12.4%
RADX RADIOPHARM THERANOSTICS LTD 0.3%
Value $739K Shares 51,000,000 Share Price $0.01 Est. Cost/Share $0.02 Unrealized @ Report Date —
MXCT MAXCYTE INC 0.3%
Value $706K Shares 1,004,673 Share Price $0.70 * Est. Cost/Share $1.36 Unrealized @ Report Date -24.0%
CDXS CODEXIS INC 0.3%
Value $681K Shares 417,994 Share Price $1.63 * Est. Cost/Share $1.95 Unrealized @ Report Date -26.7%
BOLD BOUNDLESS BIO INC 0.3%
Value $657K Shares 597,682 Share Price $1.10 * Est. Cost/Share $1.22 Unrealized @ Report Date -2.3%
HELP CYBIN INC 0.3%
Value $643K Shares 134,060 Share Price $4.80 * Est. Cost/Share $6.44 Unrealized @ Report Date +10.4%
ZNTL ZENTALIS PHARMACEUTICALS INC 0.3%
Value $630K Shares 269,100 Share Price $2.34 * Est. Cost/Share $1.56 Unrealized @ Report Date +67.1%
KTTA PASITHEA THERAPEUTICS CORP 0.2%
Value $617K Shares 831,301 Share Price $0.74 * Est. Cost/Share $0.86 Unrealized @ Report Date -0.8%
MSLE SATELLOS BIOSCIENCE INC 0.2%
Value $563K Shares 100,000 Share Price $5.63 Est. Cost/Share $5.63 Unrealized @ Report Date —
PHAT PHATHOM PHARMACEUTICALS INC 0.2%
Value $556K Shares 50,010 Share Price $11.11 * Est. Cost/Share $13.69 Unrealized @ Report Date 0.0%
OKUR ONKURE THERAPEUTICS INC 0.2%
Value $549K Shares 132,578 Share Price $4.14 * Est. Cost/Share $2.73 Unrealized @ Report Date 0.0%
XLO XILIO THERAPEUTICS INC 0.2%
Value $540K Shares 64,162 Share Price $8.41 Est. Cost/Share $8.41 Unrealized @ Report Date —
VRCA VERRICA PHARMACEUTICALS INC 0.2%
Value $528K Shares 99,735 Share Price $5.29 * Est. Cost/Share $5.54 Unrealized @ Report Date +26.6%
CADL CANDEL THERAPEUTICS INC 0.2%
Value $502K Shares 102,500 Share Price $4.90 * Est. Cost/Share $5.74 Unrealized @ Report Date 0.0%
ABEO ABEONA THERAPEUTICS INC 0.2%
Value $448K Shares 100,000 Share Price $4.48 * Est. Cost/Share $5.79 Unrealized @ Report Date -10.8%
POCI PRECISION OPTICS CORP INC MA 0.2%
Value $439K Shares 100,000 Share Price $4.39 * Est. Cost/Share $4.74 Unrealized @ Report Date 0.0%
QNRX QUOIN PHARMACEUTICALS LTD 0.1%
Value $353K Shares 53,460 Share Price $6.60 Est. Cost/Share $14.43 Unrealized @ Report Date —
ESTA ESTABLISHMENT LABS HLDGS INC 0.1%
Value $341K Shares 6,000 Share Price $56.78 * Est. Cost/Share $70.34 Unrealized @ Report Date 0.0%
UPB UPSTREAM BIO INC 0.1%
Value $315K Shares 35,000 Share Price $9.00 * Est. Cost/Share $23.68 Unrealized @ Report Date 0.0%
IRD OPUS GENETICS INC 0.1%
Value $313K Shares 68,688 Share Price $4.55 * Est. Cost/Share $2.74 Unrealized @ Report Date 0.0%
ARVN ARVINAS INC 0.1%
Value $292K Shares 27,500 Share Price $10.60 * Est. Cost/Share $12.57 Unrealized @ Report Date 0.0%
PLRX PLIANT THERAPEUTICS INC 0.1%
Value $283K Shares 224,650 Share Price $1.26 Est. Cost/Share $1.53 Unrealized @ Report Date -18.6%
JANX JANUX THERAPEUTICS INC 0.1%
Value $278K Shares 20,000 Share Price $13.90 Est. Cost/Share $23.52 Unrealized @ Report Date -41.9%
OABI OMNIAB INC 0.1%
Value $258K Shares 164,045 Share Price $1.57 * Est. Cost/Share $1.83 Unrealized @ Report Date -0.2%
XERS XERIS BIOPHARMA HOLDINGS INC 0.1%
Value $232K Shares 40,030 Share Price $5.80 * Est. Cost/Share $7.21 Unrealized @ Report Date 0.0%
CGEN COMPUGEN LTD 0.1%
Value $222K Shares 104,300 Share Price $2.13 * Est. Cost/Share $1.66 Unrealized @ Report Date +10.3%
NMRA NEUMORA THERAPEUTICS INC. 0.1%
Value $195K Shares 100,000 Share Price $1.95 * Est. Cost/Share $2.46 Unrealized @ Report Date 0.0%
SABS SAB BIOTHERAPEUTICS INC 0.1%
Value $192K Shares 50,000 Share Price $3.83 * Est. Cost/Share $4.00 Unrealized @ Report Date 0.0%
SIBN SI BONE INC 0.1%
Value $189K Shares 14,964 Share Price $12.63 * Est. Cost/Share $16.92 Unrealized @ Report Date 0.0%
EDSA EDESA BIOTECH INC 0.1%
Value $157K Shares 30,000 Share Price $5.23 * Est. Cost/Share $2.31 Unrealized @ Report Date -44.6%
CNSP CNS PHARMACEUTICALS INC 0.1%
Value $146K Shares 61,000 Share Price $2.39 * Est. Cost/Share $7.00 Unrealized @ Report Date -28.3%
PCSA PROCESSA PHARMACEUTICALS INC 0.1%
Value $139K Shares 55,000 Share Price $2.52 * Est. Cost/Share $3.72 Unrealized @ Report Date -25.3%
CABA CABALETTA BIO INC 0.1%
Value $135K Shares 50,000 Share Price $2.69 * Est. Cost/Share $2.48 Unrealized @ Report Date +5.6%
KLRS KALARIS THERAPEUTICS INC 0.0%
Value $118K Shares 20,400 Share Price $5.77 * Est. Cost/Share $9.37 Unrealized @ Report Date 0.0%
ELDN ELEDON PHARMACEUTICALS INC 0.0%
Value $108K Shares 35,000 Share Price $3.08 * Est. Cost/Share $2.38 Unrealized @ Report Date -12.3%
OVID OVID THERAPEUTICS INC 0.0%
Value $88,800 Shares 40,000 Share Price $2.22 * Est. Cost/Share $1.54 Unrealized @ Report Date +3.6%
EVAX EVAXION AS 0.0%
Value $73,332 Shares 19,713 Share Price $3.72 Est. Cost/Share $4.77 Unrealized @ Report Date —
MNKD MANNKIND CORP 0.0%
Value $39,935 Shares 16,300 Share Price $2.45 * Est. Cost/Share $4.39 Unrealized @ Report Date +26.9%
BCAB BIOATLA INC 0.0%
Value $10,527 Shares 65,387 Share Price $0.16 * Est. Cost/Share $0.27 Unrealized @ Report Date 0.0%