Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 13, 2026

Total Value: $137M (100.0% shares, 0.0% debt)

Holdings (66)

VSTM VERASTEM INC 15.4%
Value $21.09M Shares 2,732,079 Share Price $7.72 * Est. Cost/Share $6.09 Unrealized @ Report Date +46.3%
ADMA ADMA BIOLOGICS INC 9.9%
Value $13.5M Shares 740,000 Share Price $18.24 * Est. Cost/Share $2.26 Unrealized @ Report Date +644.4%
EOLS EVOLUS INC 7.9%
Value $10.85M Shares 1,631,588 Share Price $6.65 Est. Cost/Share $8.22 Unrealized @ Report Date -17.6%
ZVRA ZEVRA THERAPEUTICS INC 3.7%
Value $5.099M Shares 569,088 Share Price $8.96 * Est. Cost/Share $7.20 Unrealized @ Report Date +31.4%
IKT INHIBIKASE THERAPEUTICS INC 3.5%
Value $4.814M Shares 2,348,147 Share Price $2.05 * Est. Cost/Share $1.87 Unrealized @ Report Date -15.1%
ABEO ABEONA THERAPEUTICS INC 2.7%
Value $3.739M Shares 709,505 Share Price $5.27 * Est. Cost/Share $5.82 Unrealized @ Report Date -13.6%
NKTR NEKTAR THERAPEUTICS 2.6%
Value $3.594M Shares 85,000 Share Price $42.28 * Est. Cost/Share $20.19 Unrealized @ Report Date +177.2%
— INDIVIOR PLC 2.6%
Value $3.588M Shares 100,000 Share Price $35.88 Est. Cost/Share $10.67 Unrealized @ Report Date —
CRBP CORBUS PHARMACEUTICALS HLDGS 2.3%
Value $3.174M Shares 389,916 Share Price $8.14 * Est. Cost/Share $12.34 Unrealized @ Report Date 0.0%
KZIA KAZIA THERAPEUTICS LTD 2.3%
Value $3.172M Shares 460,359 Share Price $6.89 Est. Cost/Share $6.89 Unrealized @ Report Date —
XOMA XOMA ROYALTY CORPORATION 2.2%
Value $3.058M Shares 115,000 Share Price $26.59 * Est. Cost/Share $20.48 Unrealized @ Report Date +57.2%
VRCA VERRICA PHARMACEUTICALS INC 2.1%
Value $2.939M Shares 353,669 Share Price $8.31 * Est. Cost/Share $5.54 Unrealized @ Report Date 0.0%
HELP CYBIN INC 2.0%
Value $2.78M Shares 339,902 Share Price $8.18 * Est. Cost/Share $6.44 Unrealized @ Report Date 0.0%
TELA TELA BIO INC 2.0%
Value $2.775M Shares 2,352,032 Share Price $1.18 * Est. Cost/Share $4.03 Unrealized @ Report Date -68.6%
ACAD ACADIA PHARMACEUTICALS INC 2.0%
Value $2.671M Shares 100,000 Share Price $26.71 * Est. Cost/Share $17.77 Unrealized @ Report Date +34.5%
CRSP CRISPR THERAPEUTICS AG 1.9%
Value $2.622M Shares 50,000 Share Price $52.44 Est. Cost/Share — Unrealized @ Report Date —
SRZN SURROZEN INC 1.9%
Value $2.568M Shares 113,631 Share Price $22.60 * Est. Cost/Share $10.69 Unrealized @ Report Date +51.4%
ARE ALEXANDRIA REAL ESTATE EQ IN 1.8%
Value $2.447M Shares 50,000 Share Price $48.94 Est. Cost/Share — Unrealized @ Report Date —
XFOR X4 PHARMACEUTICALS INC 1.7%
Value $2.374M Shares 593,573 Share Price $4.00 * Est. Cost/Share $2.58 Unrealized @ Report Date +40.9%
RARE ULTRAGENYX PHARMACEUTICAL IN 1.7%
Value $2.3M Shares 100,000 Share Price $23.00 * Est. Cost/Share $29.99 Unrealized @ Report Date +9.7%
AYTU AYTU BIOPHARMA INC 1.5%
Value $2.116M Shares 813,704 Share Price $2.60 * Est. Cost/Share $1.82 Unrealized @ Report Date +23.4%
NKTR NEKTAR THERAPEUTICS 1.5%
Value $2.114M Shares 50,000 Share Price $42.28 * Est. Cost/Share $20.19 Unrealized @ Report Date +177.2%
DAWN DAY ONE BIOPHARMACEUTICALS I 1.4%
Value $1.864M Shares 200,000 Share Price $9.32 * Est. Cost/Share $10.23 Unrealized @ Report Date -18.3%
ACET ADICET BIO INC 1.4%
Value $1.852M Shares 220,011 Share Price $8.42 * Est. Cost/Share $11.05 Unrealized @ Report Date 0.0%
SPRB SPRUCE BIOSCIENCES INC 1.3%
Value $1.72M Shares 19,742 Share Price $87.11 * Est. Cost/Share $107.14 Unrealized @ Report Date 0.0%
HRTX HERON THERAPEUTICS INC 1.2%
Value $1.609M Shares 1,237,802 Share Price $1.30 * Est. Cost/Share $1.51 Unrealized @ Report Date -18.5%
ENTA ENANTA PHARMACEUTICALS INC 1.2%
Value $1.577M Shares 100,000 Share Price $15.77 * Est. Cost/Share $8.05 Unrealized @ Report Date +57.8%
PMVP PMV PHARMACEUTICALS INC 1.1%
Value $1.438M Shares 1,150,759 Share Price $1.25 * Est. Cost/Share $1.40 Unrealized @ Report Date -4.1%
CAMP CAMP4 THERAPEUTICS CORP 1.0%
Value $1.403M Shares 228,894 Share Price $6.13 * Est. Cost/Share $4.25 Unrealized @ Report Date 0.0%
ELDN ELEDON PHARMACEUTICALS INC 1.0%
Value $1.349M Shares 893,100 Share Price $1.51 * Est. Cost/Share $2.38 Unrealized @ Report Date 0.0%
MIST MILESTONE PHARMACEUTICALS IN 1.0%
Value $1.339M Shares 662,666 Share Price $2.02 * Est. Cost/Share $2.15 Unrealized @ Report Date 0.0%
OABI OMNIAB INC 0.9%
Value $1.297M Shares 701,000 Share Price $1.85 * Est. Cost/Share $1.83 Unrealized @ Report Date -4.9%
QNRX QUOIN PHARMACEUTICALS LTD 0.8%
Value $1.128M Shares 78,189 Share Price $14.43 Est. Cost/Share $14.43 Unrealized @ Report Date —
LUNG PULMONX CORP 0.8%
Value $1.075M Shares 486,400 Share Price $2.21 * Est. Cost/Share $2.50 Unrealized @ Report Date -24.7%
GERN GERON CORP 0.8%
Value $1.064M Shares 805,800 Share Price $1.32 * Est. Cost/Share $1.70 Unrealized @ Report Date -26.3%
ABEO ABEONA THERAPEUTICS INC 0.8%
Value $1.054M Shares 200,000 Share Price $5.27 * Est. Cost/Share $5.82 Unrealized @ Report Date -13.6%
CBIO CRESCENT BIOPHARMA INC. 0.8%
Value $1.04M Shares 87,682 Share Price $11.86 * Est. Cost/Share $12.74 Unrealized @ Report Date 0.0%
KZR KEZAR LIFE SCIENCES INC 0.7%
Value $982K Shares 156,179 Share Price $6.29 * Est. Cost/Share $5.01 Unrealized @ Report Date +16.5%
EDSA EDESA BIOTECH INC 0.7%
Value $976K Shares 687,500 Share Price $1.42 * Est. Cost/Share $2.31 Unrealized @ Report Date -15.3%
BOLD BOUNDLESS BIO INC 0.6%
Value $852K Shares 710,071 Share Price $1.20 Est. Cost/Share $1.22 Unrealized @ Report Date +2.3%
RADX RADIOPHARM THERANOSTICS LTD 0.6%
Value $851K Shares 51,000,000 Share Price $0.02 Est. Cost/Share $0.02 Unrealized @ Report Date —
SMLR SEMLER SCIENTIFIC INC 0.6%
Value $765K Shares 50,000 Share Price $15.29 * Est. Cost/Share $22.69 Unrealized @ Report Date 0.0%
MXCT MAXCYTE INC 0.5%
Value $727K Shares 469,018 Share Price $1.55 Est. Cost/Share $1.73 Unrealized @ Report Date -7.9%
ANTX AN2 THERAPEUTICS INC 0.5%
Value $716K Shares 627,668 Share Price $1.14 Est. Cost/Share $1.19 Unrealized @ Report Date -1.7%
GOSS GOSSAMER BIO INC 0.5%
Value $635K Shares 204,770 Share Price $3.10 * Est. Cost/Share $2.20 Unrealized @ Report Date +29.5%
ZNTL ZENTALIS PHARMACEUTICALS INC 0.5%
Value $626K Shares 463,700 Share Price $1.35 * Est. Cost/Share $1.56 Unrealized @ Report Date -7.0%
BIOA BIOAGE LABS INC 0.4%
Value $595K Shares 45,000 Share Price $13.23 * Est. Cost/Share $4.32 Unrealized @ Report Date +105.3%
MNKD MANNKIND CORP 0.4%
Value $490K Shares 86,359 Share Price $5.67 * Est. Cost/Share $4.39 Unrealized @ Report Date +25.5%
CGEN COMPUGEN LTD 0.3%
Value $467K Shares 305,400 Share Price $1.53 * Est. Cost/Share $1.66 Unrealized @ Report Date 0.0%
CDXS CODEXIS INC 0.3%
Value $417K Shares 256,106 Share Price $1.63 * Est. Cost/Share $2.28 Unrealized @ Report Date -10.4%
INAB IN8BIO INC 0.3%
Value $386K Shares 164,893 Share Price $2.34 * Est. Cost/Share $3.12 Unrealized @ Report Date -39.1%
FENC FENNEC PHARMACEUTICALS INC 0.3%
Value $385K Shares 50,000 Share Price $7.70 * Est. Cost/Share $8.21 Unrealized @ Report Date 0.0%
CABA CABALETTA BIO INC 0.3%
Value $375K Shares 171,100 Share Price $2.19 * Est. Cost/Share $2.48 Unrealized @ Report Date 0.0%
KTTA PASITHEA THERAPEUTICS CORP 0.3%
Value $355K Shares 275,062 Share Price $1.29 * Est. Cost/Share $0.88 Unrealized @ Report Date 0.0%
PLRX PLIANT THERAPEUTICS INC 0.2%
Value $281K Shares 230,050 Share Price $1.22 * Est. Cost/Share $1.53 Unrealized @ Report Date -1.5%
JANX JANUX THERAPEUTICS INC 0.2%
Value $276K Shares 20,000 Share Price $13.80 * Est. Cost/Share $23.52 Unrealized @ Report Date 0.0%
DCTH DELCATH SYS INC 0.2%
Value $275K Shares 27,232 Share Price $10.10 Est. Cost/Share $9.94 Unrealized @ Report Date 0.0%
KPRX KIORA PHARMACEUTICALS INC 0.2%
Value $258K Shares 131,144 Share Price $1.97 * Est. Cost/Share $3.90 Unrealized @ Report Date -41.5%
CNSP CNS PHARMACEUTICALS INC 0.2%
Value $256K Shares 48,827 Share Price $5.25 * Est. Cost/Share $7.50 Unrealized @ Report Date 0.0%
TNYA TENAYA THERAPEUTICS INC 0.2%
Value $250K Shares 352,001 Share Price $0.71 * Est. Cost/Share $1.36 Unrealized @ Report Date 0.0%
OVID OVID THERAPEUTICS INC 0.1%
Value $167K Shares 102,367 Share Price $1.63 * Est. Cost/Share $1.54 Unrealized @ Report Date 0.0%
TENX TENAX THERAPEUTICS INC 0.1%
Value $145K Shares 11,884 Share Price $12.19 * Est. Cost/Share $8.70 Unrealized @ Report Date 0.0%
EVAX EVAXION AS 0.1%
Value $95,400 Shares 20,000 Share Price $4.77 Est. Cost/Share $4.77 Unrealized @ Report Date —
XLO XILIO THERAPEUTICS INC 0.1%
Value $80,838 Shares 126,270 Share Price $0.64 * Est. Cost/Share $0.75 Unrealized @ Report Date 0.0%
CRIS CURIS INC 0.0%
Value $58,583 Shares 59,349 Share Price $0.99 * Est. Cost/Share $1.34 Unrealized @ Report Date 0.0%
PCSA PROCESSA PHARMACEUTICALS INC 0.0%
Value $35,490 Shares 12,323 Share Price $2.88 * Est. Cost/Share $6.99 Unrealized @ Report Date 0.0%