RTW INVESTMENTS, LP Diversified Active

CIK: 0001493215 · Show all filings

Period: Q4 2015 (← Previous) (Next →)

Filing Date: May 24, 2016

Total Value ($000): $307,386

Holdings (38)

ALNY Alnylam Pharmaceuticals Inc 17.6%

Value ($000) $53,976 Shares 573,361 Est. Cost $99.43 Unrealized -6.8%

— La Jolla Pharmaceutical Co 9.5%

Value ($000) $29,279 Shares 1,084,416 Est. Cost $25.34 Unrealized —

OMER Omeros Corp 9.3%

Value ($000) $28,618 Shares 1,819,341 Est. Cost $14.29 Unrealized -3.3%

— Kite Pharma Inc 8.4%

Value ($000) $25,815 Shares 418,935 Est. Cost $58.27 Unrealized —

— Dicerna Pharmaceuticals Inc 7.8%

Value ($000) $23,890 Shares 2,012,662 Est. Cost $13.12 Unrealized —

— Achillion Pharmaceuticals Inc 7.0%

Value ($000) $21,460 Shares 1,988,914 Est. Cost $10.93 Unrealized —

BCRX BioCryst Pharmaceuticals Inc 6.7%

Value ($000) $20,748 Shares 2,010,501 Est. Cost $11.05 Unrealized -10.0%

— Mirati Therapeutics Inc 4.0%

Value ($000) $12,180 Shares 385,456 Est. Cost $34.42 Unrealized —

— Atara Biotherapeutics Inc. 3.7%

Value ($000) $11,460 Shares 433,923 Est. Cost $26.41 Unrealized —

— Five Prime Therapeutics Inc 3.5%

Value ($000) $10,675 Shares 257,236 Est. Cost $22.81 Unrealized —

— Agenus Inc 3.3%

Value ($000) $10,054 Shares 2,214,453 Est. Cost $8.33 Unrealized —

— Celldex Therapeutics Inc 3.3%

Value ($000) $9,992 Shares 637,238 Est. Cost $20.17 Unrealized —

— Symmetry Surgical Inc 2.6%

Value ($000) $8,093 Shares 879,623 Est. Cost $8.78 Unrealized —

BMY Bristol-Myers Squibb Co 2.5%

Value ($000) $7,546 Shares 109,701 Est. Cost $45.99 Unrealized +1.5%

— Corium International Inc 2.0%

Value ($000) $6,040 Shares 743,865 Est. Cost $11.14 Unrealized —

— Global Blood Therapeutics Inc 1.8%

Value ($000) $5,663 Shares 175,156 Est. Cost $37.52 Unrealized —

— Dyax Corp 1.4%

Value ($000) $4,356 Shares 115,795 Est. Cost $14.06 Unrealized —

RGNX Regenxbio Inc 1.2%

Value ($000) $3,674 Shares 221,326 Est. Cost $25.09 Unrealized -20.9%

— Lipocine Inc 0.9%

Value ($000) $2,851 Shares 220,515 Est. Cost $5.63 Unrealized —

— Accelerate Diagnostics Inc 0.8%

Value ($000) $2,309 Shares 107,467 Est. Cost $21.49 Unrealized —

— Invuity Inc 0.6%

Value ($000) $1,789 Shares 202,808 Est. Cost $13.39 Unrealized —

— CytRx Corp 0.4%

Value ($000) $1,247 Shares 470,576 Est. Cost $2.73 Unrealized —

MASI Masimo Corp 0.3%

Value ($000) $1,075 Shares 25,900 Est. Cost $40.86 Unrealized -0.0%

ANIK Anika Therapeutics Inc 0.3%

Value ($000) $1,049 Shares 27,500 Est. Cost $38.25 Unrealized 0.0%

MDRX Allscripts Healthcare Solutions Inc 0.2%

Value ($000) $738 Shares 48,000 Est. Cost $13.76 Unrealized +4.2%

— Biopharmx Corp 0.2%

Value ($000) $563 Shares 370,636 Est. Cost $2.56 Unrealized —

— Genomic Health Inc 0.2%

Value ($000) $528 Shares 15,000 Est. Cost $21.13 Unrealized —

NTRA Natera Inc 0.1%

Value ($000) $342 Shares 31,693 Est. Cost $16.90 Unrealized -43.7%

— bluebird bio Inc 0.1%

Value ($000) $340 Shares 5,300 Est. Cost $111.52 Unrealized —

— Nivalis Therapeutics Inc 0.1%

Value ($000) $232 Shares 30,000 Est. Cost $15.17 Unrealized —

— T2 Biosystems Inc. Cmn 0.1%

Value ($000) $229 Shares 20,900 Est. Cost $10.96 Unrealized —

VCYT Veracyte Inc 0.1%

Value ($000) $180 Shares 25,000 Est. Cost $9.52 Unrealized -29.3%

— Endologix Inc 0.0%

Value ($000) $149 Shares 15,000 Est. Cost $12.27 Unrealized —

— VIVO 01/15/2016 CALL 20 0.0%

Value ($000) $110 Shares 1,252 Est. Cost — Unrealized —

ADAPY Adaptimmune Therapeutics-adr 0.0%

Value ($000) $85 Shares 7,055 Est. Cost $18.35 Unrealized —

— NVRO 05/20/2016 PUT 50 0.0%

Value ($000) $37 Shares 142 Est. Cost — Unrealized —

BRK/B Berkshire Hathaway Inc 0.0%

Value ($000) $7 Shares 50 Est. Cost $134.20 Unrealized 0.0%

— USO 01/15/2016 CALL 25 0.0%

Value ($000) $7 Shares 13,850 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ALNY	Alnylam Pharmaceuticals Inc	573,361	$53,976	17.6%	$99.43	-6.8%	—	02043Q107
—	La Jolla Pharmaceutical Co	1,084,416	$29,279	9.5%	$25.34	—	—	503459604
OMER	Omeros Corp	1,819,341	$28,618	9.3%	$14.29	-3.3%	—	682143102
—	Kite Pharma Inc	418,935	$25,815	8.4%	$58.27	—	—	49803L109
—	Dicerna Pharmaceuticals Inc	2,012,662	$23,890	7.8%	$13.12	—	—	253031108
—	Achillion Pharmaceuticals Inc	1,988,914	$21,460	7.0%	$10.93	—	—	00448Q201
BCRX	BioCryst Pharmaceuticals Inc	2,010,501	$20,748	6.7%	$11.05	-10.0%	—	09058V103
—	Mirati Therapeutics Inc	385,456	$12,180	4.0%	$34.42	—	—	60468T105
—	Atara Biotherapeutics Inc.	433,923	$11,460	3.7%	$26.41	—	—	046513107
—	Five Prime Therapeutics Inc	257,236	$10,675	3.5%	$22.81	—	—	33830X104
—	Agenus Inc	2,214,453	$10,054	3.3%	$8.33	—	—	00847G705
—	Celldex Therapeutics Inc	637,238	$9,992	3.3%	$20.17	—	—	15117B103
—	Symmetry Surgical Inc	879,623	$8,093	2.6%	$8.78	—	—	87159G100
BMY	Bristol-Myers Squibb Co	109,701	$7,546	2.5%	$45.99	+1.5%	—	110122108
—	Corium International Inc	743,865	$6,040	2.0%	$11.14	—	—	21887L107
—	Global Blood Therapeutics Inc	175,156	$5,663	1.8%	$37.52	—	—	37890U108
—	Dyax Corp	115,795	$4,356	1.4%	$14.06	—	—	26746E103
RGNX	Regenxbio Inc	221,326	$3,674	1.2%	$25.09	-20.9%	—	75901B107
—	Lipocine Inc	220,515	$2,851	0.9%	$5.63	—	—	53630X104
—	Accelerate Diagnostics Inc	107,467	$2,309	0.8%	$21.49	—	—	00430H102
—	Invuity Inc	202,808	$1,789	0.6%	$13.39	—	—	46187J205
—	CytRx Corp	470,576	$1,247	0.4%	$2.73	—	—	232828509
MASI	Masimo Corp	25,900	$1,075	0.3%	$40.86	-0.0%	—	574795100
ANIK	Anika Therapeutics Inc	27,500	$1,049	0.3%	$38.25	0.0%	—	035255108
MDRX	Allscripts Healthcare Solutions Inc	48,000	$738	0.2%	$13.76	+4.2%	—	01988P108
—	Biopharmx Corp	370,636	$563	0.2%	$2.56	—	—	09072X101
—	Genomic Health Inc	15,000	$528	0.2%	$21.13	—	—	37244C101
NTRA	Natera Inc	31,693	$342	0.1%	$16.90	-43.7%	—	632307104
—	bluebird bio Inc	5,300	$340	0.1%	$111.52	—	—	09609G100
—	Nivalis Therapeutics Inc	30,000	$232	0.1%	$15.17	—	—	65481J109
—	T2 Biosystems Inc. Cmn	20,900	$229	0.1%	$10.96	—	—	89853L104
VCYT	Veracyte Inc	25,000	$180	0.1%	$9.52	-29.3%	—	92337F107
—	Endologix Inc	15,000	$149	0.0%	$12.27	—	—	29266S106
—	VIVO 01/15/2016 CALL 20	1,252	$110	0.0%	—	—	CALL	589584101
ADAPY	Adaptimmune Therapeutics-adr	7,055	$85	0.0%	$18.35	—	—	00653A107
—	NVRO 05/20/2016 PUT 50	142	$37	0.0%	—	—	PUT	64157F103
BRK/B	Berkshire Hathaway Inc	50	$7	0.0%	$134.20	0.0%	—	084670702
—	USO 01/15/2016 CALL 25	13,850	$7	0.0%	—	—	CALL	91232N108