RTW INVESTMENTS, LP Diversified Active

Location: New York, NY

CIK: 0001493215 · Show all filings

Period: Q3 2015 (← Previous) (Next →)

Filing Date: May 24, 2016

Total Value: $322M (100.0% shares, 0.0% debt)

Holdings (44)

ALNY Alnylam Pharmaceuticals Inc 13.3%

Value $42.88M Shares 533,660 Est. Cost $99.93 Unrealized +11.2%

INCY Incyte Corp 10.4%

Value $33.45M Shares 303,212 Est. Cost $106.58 Unrealized +5.2%

— La Jolla Pharmaceutical Co 9.3%

Value $30.02M Shares 1,080,331 Est. Cost $25.34 Unrealized —

BCRX BioCryst Pharmaceuticals Inc 7.9%

Value $25.4M Shares 2,228,206 Est. Cost $11.05 Unrealized +20.8%

— Kite Pharma Inc 6.5%

Value $20.91M Shares 375,476 Est. Cost $57.88 Unrealized —

— Achillion Pharmaceuticals Inc 5.6%

Value $17.9M Shares 2,589,818 Est. Cost $10.93 Unrealized —

— Mirati Therapeutics Inc 5.2%

Value $16.59M Shares 482,069 Est. Cost $34.42 Unrealized —

— Dicerna Pharmaceuticals Inc 5.1%

Value $16.46M Shares 2,005,238 Est. Cost $13.12 Unrealized —

— bluebird bio Inc 4.0%

Value $12.97M Shares 151,594 Est. Cost $111.52 Unrealized —

— Arrowhead Research Corp 3.8%

Value $12.08M Shares 2,097,185 Est. Cost $5.76 Unrealized —

— Five Prime Therapeutics Inc 3.4%

Value $10.99M Shares 713,954 Est. Cost $22.81 Unrealized —

— Agenus Inc 3.0%

Value $9.587M Shares 2,084,142 Est. Cost $8.57 Unrealized —

— Atara Biotherapeutics Inc. 2.6%

Value $8.269M Shares 262,995 Est. Cost $31.44 Unrealized —

— Celldex Therapeutics Inc 2.4%

Value $7.575M Shares 718,729 Est. Cost $20.17 Unrealized —

— Symmetry Surgical Inc 2.2%

Value $7.186M Shares 807,442 Est. Cost $8.74 Unrealized —

BMY Bristol-Myers Squibb Co 1.9%

Value $6.064M Shares 102,425 Est. Cost $45.93 Unrealized -3.0%

— Corium International Inc 1.7%

Value $5.378M Shares 575,212 Est. Cost $12.03 Unrealized —

OMER Omeros Corp 1.7%

Value $5.37M Shares 490,000 Est. Cost $15.57 Unrealized 0.0%

RGNX Regenxbio Inc 1.4%

Value $4.505M Shares 204,494 Est. Cost $25.52 Unrealized 0.0%

— Global Blood Therapeutics Inc 1.2%

Value $3.896M Shares 92,399 Est. Cost $42.16 Unrealized —

BMY BMY 01/15/2016 CALL 60 0.8%

Value $2.588M Shares 7,500 Est. Cost $45.93 Unrealized -3.0%

— Lipocine Inc 0.8%

Value $2.514M Shares 212,497 Est. Cost $5.36 Unrealized —

— Invuity Inc 0.8%

Value $2.454M Shares 175,000 Est. Cost $14.12 Unrealized —

— Dyax Corp 0.7%

Value $2.202M Shares 115,358 Est. Cost $14.06 Unrealized —

— Presbia Plc 0.6%

Value $1.918M Shares 350,000 Est. Cost $7.39 Unrealized —

— Catalyst Biosciences Inc 0.6%

Value $1.775M Shares 380,806 Est. Cost $4.66 Unrealized —

— Repros Therapeutics Inc 0.5%

Value $1.73M Shares 232,830 Est. Cost $9.93 Unrealized —

— Vbi Vaccines Inc 0.5%

Value $1.716M Shares 650,000 Est. Cost $2.64 Unrealized —

OSUR OraSure Technologies Inc 0.4%

Value $1.434M Shares 322,996 Est. Cost $5.22 Unrealized 0.0%

— CytRx Corp 0.3%

Value $1.075M Shares 453,465 Est. Cost $2.73 Unrealized —

— NewLink Genetics Corp 0.3%

Value $1.014M Shares 28,291 Est. Cost $44.27 Unrealized —

MASI Masimo Corp 0.3%

Value $999K Shares 25,900 Est. Cost $40.86 Unrealized 0.0%

MDRX Allscripts Healthcare Solutions Inc 0.2%

Value $595K Shares 48,000 Est. Cost $13.76 Unrealized 0.0%

BCRX BCRX 12/18/2015 CALL 12 0.1%

Value $431K Shares 2,000 Est. Cost $11.05 Unrealized +20.8%

— Nivalis Therapeutics Inc 0.1%

Value $389K Shares 30,000 Est. Cost $15.17 Unrealized —

— Biopharmx Corp 0.1%

Value $382K Shares 370,636 Est. Cost $2.56 Unrealized —

NTRA Natera Inc 0.1%

Value $344K Shares 31,693 Est. Cost $16.90 Unrealized 0.0%

— Genomic Health Inc 0.1%

Value $317K Shares 15,000 Est. Cost $21.13 Unrealized —

— Endologix Inc 0.1%

Value $184K Shares 15,000 Est. Cost $12.27 Unrealized —

VCYT Veracyte Inc 0.0%

Value $117K Shares 25,000 Est. Cost $9.52 Unrealized 0.0%

ADAPY Adaptimmune Therapeutics-adr 0.0%

Value $84,000 Shares 7,028 Est. Cost $18.35 Unrealized —

— VIVO 01/15/2016 CALL 20 0.0%

Value $50,000 Shares 1,252 Est. Cost — Unrealized —

— USO 01/15/2016 CALL 25 0.0%

Value $42,000 Shares 13,850 Est. Cost $19.88 Unrealized —

— Berkshire Hathaway Inc 0.0%

Value $7,000 Shares 50 Est. Cost $140.00 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ALNY	Alnylam Pharmaceuticals Inc	533,660	$42.88M	13.3%	$99.93	+11.2%	COM	02043Q107
INCY	Incyte Corp	303,212	$33.45M	10.4%	$106.58	+5.2%	COM	45337C102
—	La Jolla Pharmaceutical Co	1,080,331	$30.02M	9.3%	$25.34	—	COM PAR $.0001 2	503459604
BCRX	BioCryst Pharmaceuticals Inc	2,228,206	$25.4M	7.9%	$11.05	+20.8%	COM	09058V103
—	Kite Pharma Inc	375,476	$20.91M	6.5%	$57.88	—	COM	49803L109
—	Achillion Pharmaceuticals Inc	2,589,818	$17.9M	5.6%	$10.93	—	COM	00448Q201
—	Mirati Therapeutics Inc	482,069	$16.59M	5.2%	$34.42	—	COM	60468T105
—	Dicerna Pharmaceuticals Inc	2,005,238	$16.46M	5.1%	$13.12	—	COM	253031108
—	bluebird bio Inc	151,594	$12.97M	4.0%	$111.52	—	COM	09609G100
—	Arrowhead Research Corp	2,097,185	$12.08M	3.8%	$5.76	—	COM NEW	42797209
—	Five Prime Therapeutics Inc	713,954	$10.99M	3.4%	$22.81	—	COM	33830X104
—	Agenus Inc	2,084,142	$9.587M	3.0%	$8.57	—	COM NEW	00847G705
—	Atara Biotherapeutics Inc.	262,995	$8.269M	2.6%	$31.44	—	COM	46513107
—	Celldex Therapeutics Inc	718,729	$7.575M	2.4%	$20.17	—	NEW COM	15117B103
—	Symmetry Surgical Inc	807,442	$7.186M	2.2%	$8.74	—	COM	87159G100
BMY	Bristol-Myers Squibb Co	102,425	$6.064M	1.9%	$45.93	-3.0%	COM	110122108
—	Corium International Inc	575,212	$5.378M	1.7%	$12.03	—	COM	21887L107
OMER	Omeros Corp	490,000	$5.37M	1.7%	$15.57	0.0%	COM	682143102
RGNX	Regenxbio Inc	204,494	$4.505M	1.4%	$25.52	0.0%	COM ADDED	75901B107
—	Global Blood Therapeutics Inc	92,399	$3.896M	1.2%	$42.16	—	COM ADDED	37890U108
BMY	BMY 01/15/2016 CALL 60	7,500	$2.588M	0.8%	$45.93	-3.0%	Call	110122108
—	Lipocine Inc	212,497	$2.514M	0.8%	$5.36	—	NEW COM	53630X104
—	Invuity Inc	175,000	$2.454M	0.8%	$14.12	—	COM NEW	46187J205
—	Dyax Corp	115,358	$2.202M	0.7%	$14.06	—	COM	26746E103
—	Presbia Plc	350,000	$1.918M	0.6%	$7.39	—	SHS	G7234P100
—	Catalyst Biosciences Inc	380,806	$1.775M	0.6%	$4.66	—	COM ADDED	14888D109
—	Repros Therapeutics Inc	232,830	$1.73M	0.5%	$9.93	—	COM NEW	76028H209
—	Vbi Vaccines Inc	650,000	$1.716M	0.5%	$2.64	—	COM	91790E102
OSUR	OraSure Technologies Inc	322,996	$1.434M	0.4%	$5.22	0.0%	COM	68554V108
—	CytRx Corp	453,465	$1.075M	0.3%	$2.73	—	COM PAR $.001	232828509
—	NewLink Genetics Corp	28,291	$1.014M	0.3%	$44.27	—	COM	651511107
MASI	Masimo Corp	25,900	$999K	0.3%	$40.86	0.0%	COM	574795100
MDRX	Allscripts Healthcare Solutions Inc	48,000	$595K	0.2%	$13.76	0.0%	COM	01988P108
BCRX	BCRX 12/18/2015 CALL 12	2,000	$431K	0.1%	$11.05	+20.8%	Call	09058V103
—	Nivalis Therapeutics Inc	30,000	$389K	0.1%	$15.17	—	COM	65481J109
—	Biopharmx Corp	370,636	$382K	0.1%	$2.56	—	COM	09072X101
NTRA	Natera Inc	31,693	$344K	0.1%	$16.90	0.0%	COM ADDED	632307104
—	Genomic Health Inc	15,000	$317K	0.1%	$21.13	—	COM	37244C101
—	Endologix Inc	15,000	$184K	0.1%	$12.27	—	COM	29266S106
VCYT	Veracyte Inc	25,000	$117K	0.0%	$9.52	0.0%	COM	92337F107
ADAPY	Adaptimmune Therapeutics-adr	7,028	$84,000	0.0%	$18.35	—	SPONDS ADR	00653A107
—	VIVO 01/15/2016 CALL 20	1,252	$50,000	0.0%	—	—	Call	589584101
—	USO 01/15/2016 CALL 25	13,850	$42,000	0.0%	$19.88	—	Call	91232N108
—	Berkshire Hathaway Inc	50	$7,000	0.0%	$140.00	—	CL B NEW	84670702