RTW INVESTMENTS, LP Diversified Active

Location: New York, NY

CIK: 0001493215 · Show all filings

Period: Q3 2018 (← Previous) (Next →)

Filing Date: Nov 14, 2018

Total Value: $1.67B (100.0% shares, 0.0% debt)

Holdings (46)

RCKT Rocket Pharmaceuticals Inc 22.1%

Value $369M Shares 14,969,744 Est. Cost $16.31 Unrealized +33.0%

PTCT PTC Therapeutics Inc 9.2%

Value $154M Shares 3,275,591 Est. Cost $13.46 Unrealized +207.4%

ARWR ARROWHEAD PHARMACEUTICALS IN 8.7%

Value $146M Shares 7,604,225 Est. Cost $8.23 Unrealized +99.5%

RGNX Regenxbio Inc 6.6%

Value $110M Shares 1,459,128 Est. Cost $24.63 Unrealized +192.6%

— Dicerna Pharmaceuticals Inc 5.0%

Value $83.34M Shares 5,461,124 Est. Cost $10.92 Unrealized —

PRQR PROQR THRAPEUTICS N V 4.3%

Value $72.36M Shares 3,739,406 Est. Cost $10.63 Unrealized 0.0%

BMY BRISTOL MYERS SQUIBB CO 3.5%

Value $58.79M Shares 946,961 Est. Cost $43.58 Unrealized +3.2%

LIVN LivaNova PLC 3.3%

Value $54.92M Shares 443,036 Est. Cost $89.75 Unrealized +31.4%

SRPT Sarepta Therapeutics Inc 3.0%

Value $50.73M Shares 314,070 Est. Cost $74.88 Unrealized +82.6%

— ACHILLION PHARMACEUTICALS IN 3.0%

Value $50.03M Shares 13,595,704 Est. Cost $3.82 Unrealized —

MASI Masimo Corp 2.3%

Value $38.66M Shares 310,461 Est. Cost $84.24 Unrealized +31.7%

ABUS Arbutus Biopharma Corp 2.3%

Value $38.6M Shares 4,084,904 Est. Cost $3.27 Unrealized +204.0%

— CORIUM INTL INC 2.1%

Value $34.34M Shares 3,610,632 Est. Cost $8.89 Unrealized —

ALNY Alnylam Pharmaceuticals Inc 2.0%

Value $34.05M Shares 389,072 Est. Cost $84.04 Unrealized +19.7%

VRAYQ Viewray Inc 1.9%

Value $31.73M Shares 3,389,498 Est. Cost $8.34 Unrealized +17.8%

VCEL Vericel Corp 1.9%

Value $31.38M Shares 2,217,916 Est. Cost $6.40 Unrealized +83.1%

ILMN Illumina Inc 1.8%

Value $30.33M Shares 82,621 Est. Cost $280.75 Unrealized +14.1%

— Qiagen NV 1.8%

Value $29.37M Shares 775,324 Est. Cost $36.71 Unrealized —

— La Jolla Pharmaceutical Co 1.4%

Value $24.1M Shares 1,197,107 Est. Cost $26.28 Unrealized —

— Agenus Inc 1.3%

Value $21.02M Shares 9,824,579 Est. Cost $5.82 Unrealized —

ESTA ESTABLISHMENT LABS HLDGS INC 1.1%

Value $18.09M Shares 775,809 Est. Cost $25.66 Unrealized 0.0%

— Myokardia Inc 1.1%

Value $17.86M Shares 273,917 Est. Cost $43.86 Unrealized —

— Principia Biopharma Inc 1.0%

Value $17.37M Shares 644,448 Est. Cost $26.95 Unrealized —

RMD ResMed Inc 1.0%

Value $17M Shares 147,400 Est. Cost $102.22 Unrealized 0.0%

— Bovie Medical Corp 1.0%

Value $15.87M Shares 2,235,547 Est. Cost $3.45 Unrealized —

QURE Uniqure NV 0.9%

Value $15.61M Shares 428,980 Est. Cost $16.23 Unrealized +129.2%

— Solid Biosciences Inc 0.7%

Value $12.38M Shares 262,318 Est. Cost $6.82 Unrealized —

PACB PACIFIC BIOSCIENCES CALIF IN 0.7%

Value $12.11M Shares 2,237,607 Est. Cost $4.29 Unrealized 0.0%

CDNA CareDx Inc 0.6%

Value $10.32M Shares 357,766 Est. Cost $7.58 Unrealized +146.9%

— Homology Medicines Inc 0.6%

Value $9.942M Shares 434,917 Est. Cost $20.70 Unrealized —

VKTX Viking Therapeutics Inc 0.5%

Value $8.71M Shares 500,000 Est. Cost $11.90 Unrealized 0.0%

— VIVEVE MED INC 0.5%

Value $8.435M Shares 3,147,232 Est. Cost $4.19 Unrealized —

— ELECTROCORE INC 0.4%

Value $7.198M Shares 514,165 Est. Cost $16.47 Unrealized —

— Odonate Therapeutics Inc 0.3%

Value $5.621M Shares 289,608 Est. Cost $22.59 Unrealized —

— Nuvectra Corp 0.3%

Value $5.524M Shares 251,329 Est. Cost $13.02 Unrealized —

— Novavax Inc 0.3%

Value $5.21M Shares 2,771,023 Est. Cost $2.09 Unrealized —

STIM Neuronetics Inc 0.3%

Value $5.049M Shares 157,487 Est. Cost $27.20 Unrealized +11.8%

— VIVUS INC 0.2%

Value $3.185M Shares 4,000,000 Est. Cost $0.80 Unrealized —

— PROTEOSTASIS THERAPEUTICS IN 0.2%

Value $2.721M Shares 1,129,121 Est. Cost $5.67 Unrealized —

ARGX ARGENX SE 0.1%

Value $2.037M Shares 26,853 Est. Cost $24.42 Unrealized —

— RA MED SYS INC 0.1%

Value $2.002M Shares 110,000 Est. Cost $18.20 Unrealized —

— Tapimmune Inc 0.1%

Value $1.898M Shares 209,721 Est. Cost $9.41 Unrealized —

— Novus Therapeutics Inc 0.1%

Value $1.477M Shares 316,257 Est. Cost $5.02 Unrealized —

— Adverum Biotechnologies Inc 0.1%

Value $1.118M Shares 184,821 Est. Cost $5.81 Unrealized —

— Bellicum Pharmaceuticals Inc 0.1%

Value $970K Shares 157,489 Est. Cost $7.32 Unrealized —

— MOTUS GI HLDGS INC 0.0%

Value $303K Shares 59,478 Est. Cost $4.48 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
RCKT	Rocket Pharmaceuticals Inc	14,969,744	$369M	22.1%	$16.31	+33.0%	COM	77313F106
PTCT	PTC Therapeutics Inc	3,275,591	$154M	9.2%	$13.46	+207.4%	COM	69366J200
ARWR	ARROWHEAD PHARMACEUTICALS IN	7,604,225	$146M	8.7%	$8.23	+99.5%	COM	04280A100
RGNX	Regenxbio Inc	1,459,128	$110M	6.6%	$24.63	+192.6%	COM	75901B107
—	Dicerna Pharmaceuticals Inc	5,461,124	$83.34M	5.0%	$10.92	—	COM	253031108
PRQR	PROQR THRAPEUTICS N V	3,739,406	$72.36M	4.3%	$10.63	0.0%	SHS EURO	N71542109
BMY	BRISTOL MYERS SQUIBB CO	946,961	$58.79M	3.5%	$43.58	+3.2%	COM	110122108
LIVN	LivaNova PLC	443,036	$54.92M	3.3%	$89.75	+31.4%	SHS	G5509L101
SRPT	Sarepta Therapeutics Inc	314,070	$50.73M	3.0%	$74.88	+82.6%	COM	803607100
—	ACHILLION PHARMACEUTICALS IN	13,595,704	$50.03M	3.0%	$3.82	—	COM	00448Q201
MASI	Masimo Corp	310,461	$38.66M	2.3%	$84.24	+31.7%	COM	574795100
ABUS	Arbutus Biopharma Corp	4,084,904	$38.6M	2.3%	$3.27	+204.0%	COM	03879J100
—	CORIUM INTL INC	3,610,632	$34.34M	2.1%	$8.89	—	COM	21887L107
ALNY	Alnylam Pharmaceuticals Inc	389,072	$34.05M	2.0%	$84.04	+19.7%	COM	02043Q107
VRAYQ	Viewray Inc	3,389,498	$31.73M	1.9%	$8.34	+17.8%	COM	92672L107
VCEL	Vericel Corp	2,217,916	$31.38M	1.9%	$6.40	+83.1%	COM	92346J108
ILMN	Illumina Inc	82,621	$30.33M	1.8%	$280.75	+14.1%	COM	452327109
—	Qiagen NV	775,324	$29.37M	1.8%	$36.71	—	SHS NEW	N72482123
—	La Jolla Pharmaceutical Co	1,197,107	$24.1M	1.4%	$26.28	—	COM PAR $.0001 2	503459604
—	Agenus Inc	9,824,579	$21.02M	1.3%	$5.82	—	COM NEW	00847G705
ESTA	ESTABLISHMENT LABS HLDGS INC	775,809	$18.09M	1.1%	$25.66	0.0%	COM	G31249108
—	Myokardia Inc	273,917	$17.86M	1.1%	$43.86	—	COM	62857M105
—	Principia Biopharma Inc	644,448	$17.37M	1.0%	$26.95	—	COM	74257L108
RMD	ResMed Inc	147,400	$17M	1.0%	$102.22	0.0%	COM	761152107
—	Bovie Medical Corp	2,235,547	$15.87M	1.0%	$3.45	—	COM	10211F100
QURE	Uniqure NV	428,980	$15.61M	0.9%	$16.23	+129.2%	SHS	N90064101
—	Solid Biosciences Inc	262,318	$12.38M	0.7%	$6.82	—	COM	83422E105
PACB	PACIFIC BIOSCIENCES CALIF IN	2,237,607	$12.11M	0.7%	$4.29	0.0%	COM	69404D108
CDNA	CareDx Inc	357,766	$10.32M	0.6%	$7.58	+146.9%	COM	14167L103
—	Homology Medicines Inc	434,917	$9.942M	0.6%	$20.70	—	COM	438083107
VKTX	Viking Therapeutics Inc	500,000	$8.71M	0.5%	$11.90	0.0%	COM	92686J106
—	VIVEVE MED INC	3,147,232	$8.435M	0.5%	$4.19	—	COM NEW	92852W204
—	ELECTROCORE INC	514,165	$7.198M	0.4%	$16.47	—	COM	28531P103
—	Odonate Therapeutics Inc	289,608	$5.621M	0.3%	$22.59	—	COM	676079106
—	Nuvectra Corp	251,329	$5.524M	0.3%	$13.02	—	COM	67075N108
—	Novavax Inc	2,771,023	$5.21M	0.3%	$2.09	—	COM	670002104
STIM	Neuronetics Inc	157,487	$5.049M	0.3%	$27.20	+11.8%	COM	64131A105
—	VIVUS INC	4,000,000	$3.185M	0.2%	$0.80	—	NOTE 4.500% 5/0	928551AB6
—	PROTEOSTASIS THERAPEUTICS IN	1,129,121	$2.721M	0.2%	$5.67	—	COM	74373B109
ARGX	ARGENX SE	26,853	$2.037M	0.1%	$24.42	—	SPONSORED ADR	04016X101
—	RA MED SYS INC	110,000	$2.002M	0.1%	$18.20	—	COM	74933X104
—	Tapimmune Inc	209,721	$1.898M	0.1%	$9.41	—	COM PAR	876033408
—	Novus Therapeutics Inc	316,257	$1.477M	0.1%	$5.02	—	COM	67011N105
—	Adverum Biotechnologies Inc	184,821	$1.118M	0.1%	$5.81	—	COM	00773U108
—	Bellicum Pharmaceuticals Inc	157,489	$970K	0.1%	$7.32	—	COM	079481107
—	MOTUS GI HLDGS INC	59,478	$303K	0.0%	$4.48	—	COM	62014P108