ARROWHEAD PHARMACEUTICALS IN

Ticker: ARWR CUSIP: 04280A100 Class: Common Stock

RTW INVESTMENTS, LP's Holding History (CIK: 0001493215)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 584,716 Value ($000) $38,819 Avg Close $49.01 Range $34.38 - $72.36

Q4 2021

Shares 346,842 Value ($000) $22,996 Avg Close $68.71 Range $57.94 - $84.83

Q2 2019

Shares 1,120,346 Value ($000) $29,689 Avg Close $21.95 Range $17.30 - $28.84

Q1 2019

Shares 1,528,213 Value ($000) $28,043 Avg Close $16.50 Range $11.67 - $20.60

Q4 2018

Shares 5,316,156 Value ($000) $66,027 Avg Close $13.67 Range $10.41 - $20.31

Q3 2018

Shares 7,604,225 Value ($000) $145,773 Avg Close $16.41 Range $12.25 - $22.39

Q2 2018

Shares 8,299,542 Value ($000) $112,874 Avg Close $9.35 Range $6.26 - $14.24

Q1 2018

Shares 2,916,561 Value ($000) $21,028 Avg Close $6.16 Range $3.57 - $8.09

Q3 2016

Shares 1,116,777 Value ($000) $8,208 Avg Close $6.48 Range $5.29 - $8.22

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	584,716	$38,819	$49.01	$34.38 - $72.36
Q4 2021	346,842	$22,996	$68.71	$57.94 - $84.83
Q2 2019	1,120,346	$29,689	$21.95	$17.30 - $28.84
Q1 2019	1,528,213	$28,043	$16.50	$11.67 - $20.60
Q4 2018	5,316,156	$66,027	$13.67	$10.41 - $20.31
Q3 2018	7,604,225	$145,773	$16.41	$12.25 - $22.39
Q2 2018	8,299,542	$112,874	$9.35	$6.26 - $14.24
Q1 2018	2,916,561	$21,028	$6.16	$3.57 - $8.09
Q3 2016	1,116,777	$8,208	$6.48	$5.29 - $8.22