Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q2 2019 (← Previous) (Next →)

Filing Date: Aug 13, 2019

Total Value ($000): $1,068,381,974 (100.0% shares, 0.0% debt)

Holdings (31)

— SPARK THERAPEUTICS INC 8.5%

Value ($000) $90,585,824 Shares 884,800 Est. Cost $60.22 Unrealized —

— INVITAE CORP 8.4%

Value ($000) $90,202,118 Shares 3,838,388 Est. Cost $10040.39 Unrealized —

— BLUEPRINT MEDICINES CORP 8.3%

Value ($000) $88,670,200 Shares 940,000 Est. Cost $9221.69 Unrealized —

CDXS CODEXIS INC 8.1%

Value ($000) $86,519,885 Shares 5,073,780 Est. Cost $13.94 Unrealized +38.3%

— SAGE THERAPEUTICS INC 6.9%

Value ($000) $73,236,000 Shares 400,000 Est. Cost $89.71 Unrealized —

— MYOKARDIA INC 6.0%

Value ($000) $64,429,900 Shares 1,285,000 Est. Cost $39.07 Unrealized —

FATE FATE THERAPEUTICS INC 4.8%

Value ($000) $51,765,000 Shares 2,550,000 Est. Cost $4.33 Unrealized +316.3%

SRPT SAREPTA THERAPEUTICS INC 4.8%

Value ($000) $50,903,250 Shares 335,000 Est. Cost $127.76 Unrealized -4.9%

— BLUEBIRD BIO INC 4.4%

Value ($000) $47,382,000 Shares 372,500 Est. Cost $5243.63 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 4.4%

Value ($000) $47,164,000 Shares 650,000 Est. Cost $81.37 Unrealized -5.7%

— MAGENTA THERAPEUTICS INC 4.1%

Value ($000) $44,296,035 Shares 3,003,121 Est. Cost $1777.95 Unrealized —

BLFS BIOLIFE SOLUTIONS INC 3.7%

Value ($000) $39,408,375 Shares 2,428,571 Est. Cost $15.38 Unrealized +13.3%

— AUDENTES THERAPEUTICS INC 3.4%

Value ($000) $36,534,900 Shares 965,000 Est. Cost $26.14 Unrealized —

VYGR VOYAGER THERAPEUTICS INC 2.9%

Value ($000) $30,706,202 Shares 1,128,075 Est. Cost $14.86 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 2.3%

Value ($000) $24,690,600 Shares 495,000 Est. Cost $62.09 Unrealized -13.9%

ILMN ILLUMINA INC 2.1%

Value ($000) $22,089,000 Shares 60,000 Est. Cost $196.93 Unrealized +60.3%

— GENMARK DIAGNOSTICS INC 2.0%

Value ($000) $21,838,850 Shares 3,365,000 Est. Cost $6.69 Unrealized —

ADPT ADAPTIVE BIOTECHNOLOGIES COR 1.9%

Value ($000) $20,100,347 Shares 463,125 Est. Cost $44.30 Unrealized 0.0%

— GRITSTONE ONCOLOGY INC 1.8%

Value ($000) $19,717,800 Shares 1,770,000 Est. Cost $4096.07 Unrealized —

— CONSTELLATION PHARMCETICLS I 1.8%

Value ($000) $18,714,229 Shares 1,523,960 Est. Cost $6.31 Unrealized —

SGMO SANGAMO THERAPEUTICS INC 1.5%

Value ($000) $16,478,100 Shares 1,530,000 Est. Cost $8.80 Unrealized +20.9%

— GLOBAL BLOOD THERAPEUTICS IN 1.5%

Value ($000) $15,780,000 Shares 300,000 Est. Cost $32.45 Unrealized —

— HOMOLOGY MEDICINES INC 1.4%

Value ($000) $14,579,650 Shares 745,000 Est. Cost $10386.26 Unrealized —

EDIT EDITAS MEDICINE INC 1.1%

Value ($000) $11,875,200 Shares 480,000 Est. Cost $29.14 Unrealized -18.1%

ALEC ALECTOR INC 1.0%

Value ($000) $10,189,059 Shares 551,039 Est. Cost $19.47 Unrealized +4.3%

TWST TWIST BIOSCIENCE CORP 0.8%

Value ($000) $8,703,000 Shares 300,000 Est. Cost $26.45 Unrealized 0.0%

DNLI DENALI THERAPEUTICS INC 0.8%

Value ($000) $8,304,000 Shares 400,000 Est. Cost $21.34 Unrealized +5.0%

CDNA CAREDX INC 0.7%

Value ($000) $7,198,000 Shares 200,000 Est. Cost $11.47 Unrealized +179.1%

STOK STOKE THERAPEUTICS INC 0.2%

Value ($000) $2,479,450 Shares 85,000 Est. Cost $26.85 Unrealized 0.0%

— TURNING POINT THERAPEUTICS I 0.2%

Value ($000) $2,442,000 Shares 60,000 Est. Cost $40700.00 Unrealized —

— ORCHARD THERAPEUTICS PLC 0.1%

Value ($000) $1,399,000 Shares 100,000 Est. Cost $13990.00 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	SPARK THERAPEUTICS INC	884,800	$90,585,824	8.5%	$60.22	—	COM	84652J103
—	INVITAE CORP	3,838,388	$90,202,118	8.4%	$10040.39	—	COM	46185L103
—	BLUEPRINT MEDICINES CORP	940,000	$88,670,200	8.3%	$9221.69	—	COM	09627Y109
CDXS	CODEXIS INC	5,073,780	$86,519,885	8.1%	$13.94	+38.3%	COM	192005106
—	SAGE THERAPEUTICS INC	400,000	$73,236,000	6.9%	$89.71	—	COM	78667J108
—	MYOKARDIA INC	1,285,000	$64,429,900	6.0%	$39.07	—	COM	62857M105
FATE	FATE THERAPEUTICS INC	2,550,000	$51,765,000	4.8%	$4.33	+316.3%	COM	31189P102
SRPT	SAREPTA THERAPEUTICS INC	335,000	$50,903,250	4.8%	$127.76	-4.9%	COM	803607100
—	BLUEBIRD BIO INC	372,500	$47,382,000	4.4%	$5243.63	—	COM	09609G100
ALNY	ALNYLAM PHARMACEUTICALS INC	650,000	$47,164,000	4.4%	$81.37	-5.7%	COM	02043Q107
—	MAGENTA THERAPEUTICS INC	3,003,121	$44,296,035	4.1%	$1777.95	—	COM	55910K108
BLFS	BIOLIFE SOLUTIONS INC	2,428,571	$39,408,375	3.7%	$15.38	+13.3%	COM	09062W204
—	AUDENTES THERAPEUTICS INC	965,000	$36,534,900	3.4%	$26.14	—	COM	05070R104
VYGR	VOYAGER THERAPEUTICS INC	1,128,075	$30,706,202	2.9%	$14.86	—	COM	92915B106
AGIO	AGIOS PHARMACEUTICALS INC	495,000	$24,690,600	2.3%	$62.09	-13.9%	COM	00847X104
ILMN	ILLUMINA INC	60,000	$22,089,000	2.1%	$196.93	+60.3%	COM	452327109
—	GENMARK DIAGNOSTICS INC	3,365,000	$21,838,850	2.0%	$6.69	—	COM	372309104
ADPT	ADAPTIVE BIOTECHNOLOGIES COR	463,125	$20,100,347	1.9%	$44.30	0.0%	COM	00650F109
—	GRITSTONE ONCOLOGY INC	1,770,000	$19,717,800	1.8%	$4096.07	—	COM	39868T105
—	CONSTELLATION PHARMCETICLS I	1,523,960	$18,714,229	1.8%	$6.31	—	COM	210373106
SGMO	SANGAMO THERAPEUTICS INC	1,530,000	$16,478,100	1.5%	$8.80	+20.9%	COM	800677106
—	GLOBAL BLOOD THERAPEUTICS IN	300,000	$15,780,000	1.5%	$32.45	—	COM	37890U108
—	HOMOLOGY MEDICINES INC	745,000	$14,579,650	1.4%	$10386.26	—	COM	438083107
EDIT	EDITAS MEDICINE INC	480,000	$11,875,200	1.1%	$29.14	-18.1%	COM	28106W103
ALEC	ALECTOR INC	551,039	$10,189,059	1.0%	$19.47	+4.3%	COM	014442107
TWST	TWIST BIOSCIENCE CORP	300,000	$8,703,000	0.8%	$26.45	0.0%	COM	90184D100
DNLI	DENALI THERAPEUTICS INC	400,000	$8,304,000	0.8%	$21.34	+5.0%	COM	24823R105
CDNA	CAREDX INC	200,000	$7,198,000	0.7%	$11.47	+179.1%	COM	14167L103
STOK	STOKE THERAPEUTICS INC	85,000	$2,479,450	0.2%	$26.85	0.0%	COM	86150R107
—	TURNING POINT THERAPEUTICS I	60,000	$2,442,000	0.2%	$40700.00	—	COM	90041T108
—	ORCHARD THERAPEUTICS PLC	100,000	$1,399,000	0.1%	$13990.00	—	ADR	68570P101