Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q3 2019 (← Previous) (Next →)

Filing Date: Jan 3, 2020

Total Value ($000): $966,300,626 (100.0% shares, 0.0% debt)

Holdings (33)

— SPARK THERAPEUTICS INC 8.7%

Value ($000) $83,722,834 Shares 863,300 Est. Cost $60.22 Unrealized —

— INVITAE CORP 7.7%

Value ($000) $73,965,737 Shares 3,838,388 Est. Cost $10040.39 Unrealized —

CDXS CODEXIS INC 7.2%

Value ($000) $69,586,892 Shares 5,073,780 Est. Cost $13.94 Unrealized +12.8%

— BLUEPRINT MEDICINES CORP 7.1%

Value ($000) $69,061,800 Shares 940,000 Est. Cost $9221.69 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 6.9%

Value ($000) $66,281,600 Shares 880,000 Est. Cost $121.78 Unrealized -3.0%

— MYOKARDIA INC 6.0%

Value ($000) $58,147,250 Shares 1,115,000 Est. Cost $39.07 Unrealized —

— BLUEBIRD BIO INC 5.8%

Value ($000) $56,239,750 Shares 612,500 Est. Cost $39167.43 Unrealized —

— SAGE THERAPEUTICS INC 5.8%

Value ($000) $56,116,000 Shares 400,000 Est. Cost $89.71 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 5.0%

Value ($000) $48,252,000 Shares 600,000 Est. Cost $81.37 Unrealized -2.8%

BLFS BIOLIFE SOLUTIONS INC 4.2%

Value ($000) $40,374,993 Shares 2,428,571 Est. Cost $15.38 Unrealized +22.0%

FATE FATE THERAPEUTICS INC 4.1%

Value ($000) $39,601,500 Shares 2,550,000 Est. Cost $4.33 Unrealized +342.9%

— MAGENTA THERAPEUTICS INC 3.2%

Value ($000) $31,273,721 Shares 3,048,121 Est. Cost $1903.17 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 3.1%

Value ($000) $30,294,000 Shares 935,000 Est. Cost $52.35 Unrealized -20.9%

— AUDENTES THERAPEUTICS INC 2.5%

Value ($000) $24,157,400 Shares 860,000 Est. Cost $26.14 Unrealized —

CDNA CAREDX INC 2.3%

Value ($000) $22,610,000 Shares 1,000,000 Est. Cost $24.45 Unrealized +13.3%

— GENMARK DIAGNOSTICS INC 2.1%

Value ($000) $20,391,900 Shares 3,365,000 Est. Cost $6.69 Unrealized —

VYGR VOYAGER THERAPEUTICS INC 2.0%

Value ($000) $19,414,171 Shares 1,128,075 Est. Cost $14.86 Unrealized —

ILMN ILLUMINA INC 1.9%

Value ($000) $18,253,200 Shares 60,000 Est. Cost $196.93 Unrealized +49.7%

— GRITSTONE ONCOLOGY INC 1.6%

Value ($000) $15,283,950 Shares 1,770,000 Est. Cost $4096.07 Unrealized —

— HOMOLOGY MEDICINES INC 1.5%

Value ($000) $14,842,000 Shares 820,000 Est. Cost $11091.79 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 1.5%

Value ($000) $14,556,000 Shares 300,000 Est. Cost $32.45 Unrealized —

ADPT ADAPTIVE BIOTECHNOLOGIES COR 1.5%

Value ($000) $14,310,562 Shares 463,125 Est. Cost $44.30 Unrealized -7.9%

SGMO SANGAMO THERAPEUTICS INC 1.4%

Value ($000) $13,167,750 Shares 1,455,000 Est. Cost $8.80 Unrealized +27.5%

ALEC ALECTOR INC 1.2%

Value ($000) $11,695,182 Shares 811,039 Est. Cost $19.01 Unrealized -5.1%

DNLI DENALI THERAPEUTICS INC 1.0%

Value ($000) $9,958,000 Shares 650,000 Est. Cost $20.48 Unrealized -6.7%

— CONSTELLATION PHARMCETICLS I 1.0%

Value ($000) $9,844,782 Shares 1,523,960 Est. Cost $6.31 Unrealized —

EDIT EDITAS MEDICINE INC 1.0%

Value ($000) $9,437,100 Shares 415,000 Est. Cost $29.14 Unrealized -15.0%

TWST TWIST BIOSCIENCE CORP 0.7%

Value ($000) $7,164,000 Shares 300,000 Est. Cost $26.45 Unrealized +9.9%

FULC FULCRUM THERAPEUTICS INC 0.6%

Value ($000) $5,606,052 Shares 844,285 Est. Cost $11.06 Unrealized 0.0%

— ORCHARD THERAPEUTICS PLC 0.4%

Value ($000) $3,682,800 Shares 310,000 Est. Cost $12560.65 Unrealized —

— DECIPHERA PHARMACEUTICALS IN 0.4%

Value ($000) $3,394,000 Shares 100,000 Est. Cost $33940.00 Unrealized —

— TURNING POINT THERAPEUTICS I 0.3%

Value ($000) $2,820,000 Shares 75,000 Est. Cost $40080.00 Unrealized —

STOK STOKE THERAPEUTICS INC 0.3%

Value ($000) $2,793,700 Shares 130,000 Est. Cost $27.21 Unrealized +2.5%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	SPARK THERAPEUTICS INC	863,300	$83,722,834	8.7%	$60.22	—	COM	84652J103
—	INVITAE CORP	3,838,388	$73,965,737	7.7%	$10040.39	—	COM	46185L103
CDXS	CODEXIS INC	5,073,780	$69,586,892	7.2%	$13.94	+12.8%	COM	192005106
—	BLUEPRINT MEDICINES CORP	940,000	$69,061,800	7.1%	$9221.69	—	COM	09627Y109
SRPT	SAREPTA THERAPEUTICS INC	880,000	$66,281,600	6.9%	$121.78	-3.0%	COM	803607100
—	MYOKARDIA INC	1,115,000	$58,147,250	6.0%	$39.07	—	COM	62857M105
—	BLUEBIRD BIO INC	612,500	$56,239,750	5.8%	$39167.43	—	COM	09609G100
—	SAGE THERAPEUTICS INC	400,000	$56,116,000	5.8%	$89.71	—	COM	78667J108
ALNY	ALNYLAM PHARMACEUTICALS INC	600,000	$48,252,000	5.0%	$81.37	-2.8%	COM	02043Q107
BLFS	BIOLIFE SOLUTIONS INC	2,428,571	$40,374,993	4.2%	$15.38	+22.0%	COM	09062W204
FATE	FATE THERAPEUTICS INC	2,550,000	$39,601,500	4.1%	$4.33	+342.9%	COM	31189P102
—	MAGENTA THERAPEUTICS INC	3,048,121	$31,273,721	3.2%	$1903.17	—	COM	55910K108
AGIO	AGIOS PHARMACEUTICALS INC	935,000	$30,294,000	3.1%	$52.35	-20.9%	COM	00847X104
—	AUDENTES THERAPEUTICS INC	860,000	$24,157,400	2.5%	$26.14	—	COM	05070R104
CDNA	CAREDX INC	1,000,000	$22,610,000	2.3%	$24.45	+13.3%	COM	14167L103
—	GENMARK DIAGNOSTICS INC	3,365,000	$20,391,900	2.1%	$6.69	—	COM	372309104
VYGR	VOYAGER THERAPEUTICS INC	1,128,075	$19,414,171	2.0%	$14.86	—	COM	92915B106
ILMN	ILLUMINA INC	60,000	$18,253,200	1.9%	$196.93	+49.7%	COM	452327109
—	GRITSTONE ONCOLOGY INC	1,770,000	$15,283,950	1.6%	$4096.07	—	COM	39868T105
—	HOMOLOGY MEDICINES INC	820,000	$14,842,000	1.5%	$11091.79	—	COM	438083107
—	GLOBAL BLOOD THERAPEUTICS IN	300,000	$14,556,000	1.5%	$32.45	—	COM	37890U108
ADPT	ADAPTIVE BIOTECHNOLOGIES COR	463,125	$14,310,562	1.5%	$44.30	-7.9%	COM	00650F109
SGMO	SANGAMO THERAPEUTICS INC	1,455,000	$13,167,750	1.4%	$8.80	+27.5%	COM	800677106
ALEC	ALECTOR INC	811,039	$11,695,182	1.2%	$19.01	-5.1%	COM	014442107
DNLI	DENALI THERAPEUTICS INC	650,000	$9,958,000	1.0%	$20.48	-6.7%	COM	24823R105
—	CONSTELLATION PHARMCETICLS I	1,523,960	$9,844,782	1.0%	$6.31	—	COM	210373106
EDIT	EDITAS MEDICINE INC	415,000	$9,437,100	1.0%	$29.14	-15.0%	COM	28106W103
TWST	TWIST BIOSCIENCE CORP	300,000	$7,164,000	0.7%	$26.45	+9.9%	COM	90184D100
FULC	FULCRUM THERAPEUTICS INC	844,285	$5,606,052	0.6%	$11.06	0.0%	COM	359616109
—	ORCHARD THERAPEUTICS PLC	310,000	$3,682,800	0.4%	$12560.65	—	ADR	68570P101
—	DECIPHERA PHARMACEUTICALS IN	100,000	$3,394,000	0.4%	$33940.00	—	COM	24344T101
—	TURNING POINT THERAPEUTICS I	75,000	$2,820,000	0.3%	$40080.00	—	COM	90041T108
STOK	STOKE THERAPEUTICS INC	130,000	$2,793,700	0.3%	$27.21	+2.5%	COM	86150R107