Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q1 2020 (← Previous) (Next →)

Filing Date: May 15, 2020

Total Value ($000): $942,016 (100.0% shares, 0.0% debt)

Holdings (38)

— BLUEPRINT MEDICINES CORP 9.6%

Value ($000) $90,644 Shares 1,550,000 Est. Cost $5615.52 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 7.0%

Value ($000) $65,539 Shares 670,000 Est. Cost $121.78 Unrealized -6.1%

ALNY ALNYLAM PHARMACEUTICALS INC 6.8%

Value ($000) $63,677 Shares 585,000 Est. Cost $85.45 Unrealized +35.1%

FATE FATE THERAPEUTICS INC 6.0%

Value ($000) $56,636 Shares 2,550,000 Est. Cost $4.33 Unrealized +484.3%

CDXS CODEXIS INC 6.0%

Value ($000) $56,623 Shares 5,073,780 Est. Cost $13.94 Unrealized +0.2%

— BLUEBIRD BIO INC 5.4%

Value ($000) $50,786 Shares 1,105,000 Est. Cost $21744.46 Unrealized —

— INVITAE CORP 5.0%

Value ($000) $47,550 Shares 3,478,388 Est. Cost $10040.39 Unrealized —

— MYOKARDIA INC 5.0%

Value ($000) $46,646 Shares 995,000 Est. Cost $39.07 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 4.0%

Value ($000) $37,964 Shares 1,070,000 Est. Cost $50.94 Unrealized -9.3%

— CONSTELLATION PHARMCETICLS I 3.3%

Value ($000) $30,801 Shares 980,000 Est. Cost $6.31 Unrealized —

TWST TWIST BIOSCIENCE CORP 3.2%

Value ($000) $30,580 Shares 1,000,000 Est. Cost $26.75 Unrealized +0.5%

RVMD REVOLUTION MEDICINES INC 3.1%

Value ($000) $28,911 Shares 1,319,536 Est. Cost $27.68 Unrealized 0.0%

CDNA CAREDX INC 3.0%

Value ($000) $28,255 Shares 1,294,335 Est. Cost $24.07 Unrealized -6.9%

ALEC ALECTOR INC 2.8%

Value ($000) $25,965 Shares 1,076,039 Est. Cost $18.52 Unrealized +37.6%

DNLI DENALI THERAPEUTICS INC 2.7%

Value ($000) $25,477 Shares 1,455,000 Est. Cost $18.95 Unrealized +10.1%

BLFS BIOLIFE SOLUTIONS INC 2.5%

Value ($000) $23,451 Shares 2,468,571 Est. Cost $15.40 Unrealized -10.8%

ADPT ADAPTIVE BIOTECHNOLOGIES COR 2.3%

Value ($000) $22,033 Shares 793,125 Est. Cost $37.47 Unrealized -25.6%

— MAGENTA THERAPEUTICS INC 2.0%

Value ($000) $18,658 Shares 2,971,034 Est. Cost $1872.70 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 1.6%

Value ($000) $15,327 Shares 300,000 Est. Cost $32.45 Unrealized —

FULC FULCRUM THERAPEUTICS INC 1.5%

Value ($000) $14,439 Shares 1,209,285 Est. Cost $10.58 Unrealized +51.1%

— GENMARK DIAGNOSTICS INC 1.5%

Value ($000) $13,864 Shares 3,365,000 Est. Cost $6.69 Unrealized —

— GRITSTONE ONCOLOGY INC 1.4%

Value ($000) $13,211 Shares 2,270,000 Est. Cost $3195.68 Unrealized —

GILD GILEAD SCIENCES INC 1.4%

Value ($000) $13,083 Shares 175,000 Est. Cost $54.92 Unrealized 0.0%

CRSP CRISPR THERAPEUTICS AG 1.2%

Value ($000) $11,299 Shares 266,430 Est. Cost $51.63 Unrealized 0.0%

— SAGE THERAPEUTICS INC 1.2%

Value ($000) $11,057 Shares 385,000 Est. Cost $65.16 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 1.2%

Value ($000) $10,991 Shares 1,125,000 Est. Cost $9.77 Unrealized —

VYGR VOYAGER THERAPEUTICS INC 1.1%

Value ($000) $10,020 Shares 1,095,075 Est. Cost $14.86 Unrealized —

ZLAB ZAI LAB LTD 1.0%

Value ($000) $9,781 Shares 190,000 Est. Cost $51.48 Unrealized —

ALLO ALLOGENE THERAPEUTICS INC 1.0%

Value ($000) $9,720 Shares 500,000 Est. Cost $23.82 Unrealized 0.0%

— BRISTOL-MYERS SQUIBB CO 1.0%

Value ($000) $9,500 Shares 2,500,000 Est. Cost $3.33 Unrealized —

SGMO SANGAMO THERAPEUTICS INC 1.0%

Value ($000) $9,268 Shares 1,455,000 Est. Cost $8.80 Unrealized -15.6%

ILMN ILLUMINA INC 0.9%

Value ($000) $8,194 Shares 30,000 Est. Cost $196.93 Unrealized +42.0%

— ORCHARD THERAPEUTICS PLC 0.8%

Value ($000) $7,342 Shares 975,000 Est. Cost $4002.03 Unrealized —

BDTX BLACK DIAMOND THERAPEUTICS I 0.8%

Value ($000) $7,220 Shares 289,395 Est. Cost $30.22 Unrealized 0.0%

— DECIPHERA PHARMACEUTICALS IN 0.6%

Value ($000) $5,764 Shares 140,000 Est. Cost $13347.64 Unrealized —

DMTKQ DERMTECH INC 0.6%

Value ($000) $5,642 Shares 571,713 Est. Cost $9.87 Unrealized —

— TURNING POINT THERAPEUTICS I 0.4%

Value ($000) $3,350 Shares 75,000 Est. Cost $40080.00 Unrealized —

STOK STOKE THERAPEUTICS INC 0.3%

Value ($000) $2,748 Shares 120,000 Est. Cost $27.21 Unrealized -9.2%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	BLUEPRINT MEDICINES CORP	1,550,000	$90,644	9.6%	$5615.52	—	COM	09627Y109
SRPT	SAREPTA THERAPEUTICS INC	670,000	$65,539	7.0%	$121.78	-6.1%	COM	803607100
ALNY	ALNYLAM PHARMACEUTICALS INC	585,000	$63,677	6.8%	$85.45	+35.1%	COM	02043Q107
FATE	FATE THERAPEUTICS INC	2,550,000	$56,636	6.0%	$4.33	+484.3%	COM	31189P102
CDXS	CODEXIS INC	5,073,780	$56,623	6.0%	$13.94	+0.2%	COM	192005106
—	BLUEBIRD BIO INC	1,105,000	$50,786	5.4%	$21744.46	—	COM	09609G100
—	INVITAE CORP	3,478,388	$47,550	5.0%	$10040.39	—	COM	46185L103
—	MYOKARDIA INC	995,000	$46,646	5.0%	$39.07	—	COM	62857M105
AGIO	AGIOS PHARMACEUTICALS INC	1,070,000	$37,964	4.0%	$50.94	-9.3%	COM	00847X104
—	CONSTELLATION PHARMCETICLS I	980,000	$30,801	3.3%	$6.31	—	COM	210373106
TWST	TWIST BIOSCIENCE CORP	1,000,000	$30,580	3.2%	$26.75	+0.5%	COM	90184D100
RVMD	REVOLUTION MEDICINES INC	1,319,536	$28,911	3.1%	$27.68	0.0%	COM	76155X100
CDNA	CAREDX INC	1,294,335	$28,255	3.0%	$24.07	-6.9%	COM	14167L103
ALEC	ALECTOR INC	1,076,039	$25,965	2.8%	$18.52	+37.6%	COM	014442107
DNLI	DENALI THERAPEUTICS INC	1,455,000	$25,477	2.7%	$18.95	+10.1%	COM	24823R105
BLFS	BIOLIFE SOLUTIONS INC	2,468,571	$23,451	2.5%	$15.40	-10.8%	COM NEW	09062W204
ADPT	ADAPTIVE BIOTECHNOLOGIES COR	793,125	$22,033	2.3%	$37.47	-25.6%	COM	00650F109
—	MAGENTA THERAPEUTICS INC	2,971,034	$18,658	2.0%	$1872.70	—	COM	55910K108
—	GLOBAL BLOOD THERAPEUTICS IN	300,000	$15,327	1.6%	$32.45	—	COM	37890U108
FULC	FULCRUM THERAPEUTICS INC	1,209,285	$14,439	1.5%	$10.58	+51.1%	COM	359616109
—	GENMARK DIAGNOSTICS INC	3,365,000	$13,864	1.5%	$6.69	—	COM	372309104
—	GRITSTONE ONCOLOGY INC	2,270,000	$13,211	1.4%	$3195.68	—	COM	39868T105
GILD	GILEAD SCIENCES INC	175,000	$13,083	1.4%	$54.92	0.0%	COM	375558103
CRSP	CRISPR THERAPEUTICS AG	266,430	$11,299	1.2%	$51.63	0.0%	NAMEN AKT	H17182108
—	SAGE THERAPEUTICS INC	385,000	$11,057	1.2%	$65.16	—	COM	78667J108
—	ADVERUM BIOTECHNOLOGIES INC	1,125,000	$10,991	1.2%	$9.77	—	COM	00773U108
VYGR	VOYAGER THERAPEUTICS INC	1,095,075	$10,020	1.1%	$14.86	—	COM	92915B106
ZLAB	ZAI LAB LTD	190,000	$9,781	1.0%	$51.48	—	ADR	98887Q104
ALLO	ALLOGENE THERAPEUTICS INC	500,000	$9,720	1.0%	$23.82	0.0%	COM	019770106
—	BRISTOL-MYERS SQUIBB CO	2,500,000	$9,500	1.0%	$3.33	—	RIGHT	110122157
SGMO	SANGAMO THERAPEUTICS INC	1,455,000	$9,268	1.0%	$8.80	-15.6%	COM	800677106
ILMN	ILLUMINA INC	30,000	$8,194	0.9%	$196.93	+42.0%	COM	452327109
—	ORCHARD THERAPEUTICS PLC	975,000	$7,342	0.8%	$4002.03	—	ADS	68570P101
BDTX	BLACK DIAMOND THERAPEUTICS I	289,395	$7,220	0.8%	$30.22	0.0%	COM	09203E105
—	DECIPHERA PHARMACEUTICALS IN	140,000	$5,764	0.6%	$13347.64	—	COM	24344T101
DMTKQ	DERMTECH INC	571,713	$5,642	0.6%	$9.87	—	COM	24984K105
—	TURNING POINT THERAPEUTICS I	75,000	$3,350	0.4%	$40080.00	—	COM	90041T108
STOK	STOKE THERAPEUTICS INC	120,000	$2,748	0.3%	$27.21	-9.2%	COM	86150R107