Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q1 2022 (← Previous) (Next →)

Filing Date: May 16, 2022

Total Value: $241M (100.0% shares, 0.0% debt)

Holdings (28)

— AMRYT PHARMA PLC - SPNR ADR 21.7%

Value $52.42M Shares 6,338,200 Share Price $8.27 Est. Cost/Share $12.42 Unrealized @ Report Date —

— CTI BIOPHARMA CORP 9.1%

Value $21.88M Shares 4,684,404 Share Price $4.67 Est. Cost/Share $2.49 Unrealized @ Report Date —

XERS XERIS BIOPHARMA HOLDINGS INC 8.4%

Value $20.29M Shares 7,924,056 Share Price $2.56 * Est. Cost/Share $2.24 Unrealized @ Report Date +9.0%

— AMARIN CORP PLC -ADR 6.7%

Value $16.16M Shares 4,912,714 Share Price $3.29 Est. Cost/Share $3.29 Unrealized @ Report Date —

OVID OVID THERAPEUTICS INC 5.5%

Value $13.24M Shares 4,218,069 Share Price $3.14 Est. Cost/Share $3.43 Unrealized @ Report Date -8.2%

ADMA ADMA BIOLOGICS INC 5.4%

Value $13.05M Shares 7,131,808 Share Price $1.83 * Est. Cost/Share $1.31 Unrealized @ Report Date +18.7%

— ANTARES PHARMA INC 5.3%

Value $12.83M Shares 3,130,192 Share Price $4.10 Est. Cost/Share $3.72 Unrealized @ Report Date —

— CONFORMIS INC 4.5%

Value $10.78M Shares 17,281,386 Share Price $0.62 Est. Cost/Share $0.75 Unrealized @ Report Date —

— APOLLO ENDOSURGERY INC 4.3%

Value $10.25M Shares 1,693,834 Share Price $6.05 Est. Cost/Share $5.72 Unrealized @ Report Date —

XGN EXAGEN INC 3.7%

Value $9.002M Shares 1,121,040 Share Price $8.03 * Est. Cost/Share $12.22 Unrealized @ Report Date -29.5%

ENTA ENANTA PHARMACEUTICALS INC 3.5%

Value $8.54M Shares 119,972 Share Price $71.18 * Est. Cost/Share $65.07 Unrealized @ Report Date 0.0%

LGND LIGAND PHARMACEUTICALS 3.4%

Value $8.291M Shares 73,700 Share Price $112.50 * Est. Cost/Share $72.55 Unrealized @ Report Date 0.0%

— OPTINOSE INC 3.0%

Value $7.228M Shares 2,926,416 Share Price $2.47 Est. Cost/Share $1.62 Unrealized @ Report Date —

— QUIDEL CORP 2.9%

Value $6.949M Shares 61,791 Share Price $112.46 Est. Cost/Share $112.46 Unrealized @ Report Date —

EOLS EVOLUS INC 2.7%

Value $6.577M Shares 586,224 Share Price $11.22 * Est. Cost/Share $7.42 Unrealized @ Report Date +14.9%

ATYR ATYR PHARMA INC 1.3%

Value $3.218M Shares 601,580 Share Price $5.35 * Est. Cost/Share $6.39 Unrealized @ Report Date -11.4%

DMAC DIAMEDICA THERAPEUTICS INC 1.2%

Value $2.993M Shares 1,197,245 Share Price $2.50 * Est. Cost/Share $4.07 Unrealized @ Report Date -30.3%

— SYNLOGIC INC 1.1%

Value $2.554M Shares 1,064,135 Share Price $2.40 Est. Cost/Share $3.01 Unrealized @ Report Date —

RZLT REZOLUTE INC 1.0%

Value $2.531M Shares 748,702 Share Price $3.38 * Est. Cost/Share $5.84 Unrealized @ Report Date -34.1%

URGN UROGEN PHARMA LTD 1.0%

Value $2.342M Shares 268,833 Share Price $8.71 * Est. Cost/Share $7.80 Unrealized @ Report Date 0.0%

— SURGALIGN HOLDINGS INC 0.9%

Value $2.244M Shares 7,375,678 Share Price $0.30 Est. Cost/Share $0.30 Unrealized @ Report Date —

CELC CELCUITY INC 0.9%

Value $2.239M Shares 239,433 Share Price $9.35 * Est. Cost/Share $20.31 Unrealized @ Report Date -48.8%

— CIDARA THERAPEUTICS INC 0.9%

Value $2.079M Shares 2,496,520 Share Price $0.83 Est. Cost/Share $1.47 Unrealized @ Report Date —

XOMA XOMA CORP 0.4%

Value $1.03M Shares 36,803 Share Price $27.99 * Est. Cost/Share $20.24 Unrealized @ Report Date +12.7%

— AERIE PHARMACEUTICALS INC 0.4%

Value $854K Shares 93,900 Share Price $9.09 Est. Cost/Share $9.09 Unrealized @ Report Date —

ANIP ANI PHARMACEUTICALS INC 0.3%

Value $733K Shares 26,060 Share Price $28.13 * Est. Cost/Share $42.97 Unrealized @ Report Date -13.2%

— MARINUS PHARMACEUTICALS INC 0.2%

Value $531K Shares 56,747 Share Price $9.36 Est. Cost/Share $9.36 Unrealized @ Report Date —

NMTC NEUROONE MEDICAL TECHNOLOGIE 0.1%

Value $273K Shares 248,105 Share Price $1.10 * Est. Cost/Share $2.70 Unrealized @ Report Date -25.1%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
—	AMRYT PHARMA PLC - SPNR ADR	6,338,200	$52.42M	21.7%	$8.27	$12.42	—	SPONSORED ADS	03217L106
—	CTI BIOPHARMA CORP	4,684,404	$21.88M	9.1%	$4.67	$2.49	—	COM	12648L601
XERS	XERIS BIOPHARMA HOLDINGS INC	7,924,056	$20.29M	8.4%	$2.56 *	$2.24	+9.0%	COM	98422E103
—	AMARIN CORP PLC -ADR	4,912,714	$16.16M	6.7%	$3.29	$3.29	—	SPONS ADR NEW	023111206
OVID	OVID THERAPEUTICS INC	4,218,069	$13.24M	5.5%	$3.14	$3.43	-8.2%	COM	690469101
ADMA	ADMA BIOLOGICS INC	7,131,808	$13.05M	5.4%	$1.83 *	$1.31	+18.7%	COM	000899104
—	ANTARES PHARMA INC	3,130,192	$12.83M	5.3%	$4.10	$3.72	—	COM	036642106
—	CONFORMIS INC	17,281,386	$10.78M	4.5%	$0.62	$0.75	—	COM	20717E101
—	APOLLO ENDOSURGERY INC	1,693,834	$10.25M	4.3%	$6.05	$5.72	—	COM	03767D108
XGN	EXAGEN INC	1,121,040	$9.002M	3.7%	$8.03 *	$12.22	-29.5%	COM	30068X103
ENTA	ENANTA PHARMACEUTICALS INC	119,972	$8.54M	3.5%	$71.18 *	$65.07	0.0%	COM	29251M106
LGND	LIGAND PHARMACEUTICALS	73,700	$8.291M	3.4%	$112.50 *	$72.55	0.0%	COM NEW	53220K504
—	OPTINOSE INC	2,926,416	$7.228M	3.0%	$2.47	$1.62	—	COM	68404V100
—	QUIDEL CORP	61,791	$6.949M	2.9%	$112.46	$112.46	—	COM	74838J101
EOLS	EVOLUS INC	586,224	$6.577M	2.7%	$11.22 *	$7.42	+14.9%	COM	30052C107
ATYR	ATYR PHARMA INC	601,580	$3.218M	1.3%	$5.35 *	$6.39	-11.4%	COM NEW	002120202
DMAC	DIAMEDICA THERAPEUTICS INC	1,197,245	$2.993M	1.2%	$2.50 *	$4.07	-30.3%	COM NEW	25253X207
—	SYNLOGIC INC	1,064,135	$2.554M	1.1%	$2.40	$3.01	—	COM	87166L100
RZLT	REZOLUTE INC	748,702	$2.531M	1.0%	$3.38 *	$5.84	-34.1%	COM NEW	76200L309
URGN	UROGEN PHARMA LTD	268,833	$2.342M	1.0%	$8.71 *	$7.80	0.0%	COM	M96088105
—	SURGALIGN HOLDINGS INC	7,375,678	$2.244M	0.9%	$0.30	$0.30	—	COM	86882C105
CELC	CELCUITY INC	239,433	$2.239M	0.9%	$9.35 *	$20.31	-48.8%	COM	15102K100
—	CIDARA THERAPEUTICS INC	2,496,520	$2.079M	0.9%	$0.83	$1.47	—	COM	171757107
XOMA	XOMA CORP	36,803	$1.03M	0.4%	$27.99 *	$20.24	+12.7%	COM NEW	98419J206
—	AERIE PHARMACEUTICALS INC	93,900	$854K	0.4%	$9.09	$9.09	—	COM	00771V108
ANIP	ANI PHARMACEUTICALS INC	26,060	$733K	0.3%	$28.13 *	$42.97	-13.2%	COM	00182C103
—	MARINUS PHARMACEUTICALS INC	56,747	$531K	0.2%	$9.36	$9.36	—	COM NEW	56854Q200
NMTC	NEUROONE MEDICAL TECHNOLOGIE	248,105	$273K	0.1%	$1.10 *	$2.70	-25.1%	COM NEW	64130M209