Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q2 2022 (← Previous) (Next →)

Filing Date: Aug 12, 2022

Total Value: $215M (100.0% shares, 0.0% debt)

Holdings (25)

— AMRYT PHARMA PLC - SPNR ADR 20.5%

Value $44.02M Shares 6,298,348 Share Price $6.99 Est. Cost/Share $12.42 Unrealized @ Report Date —

— CTI BIOPHARMA CORP 10.2%

Value $21.98M Shares 3,681,195 Share Price $5.97 Est. Cost/Share $2.49 Unrealized @ Report Date —

XERS XERIS BIOPHARMA HOLDINGS INC 8.3%

Value $17.94M Shares 11,647,417 Share Price $1.54 * Est. Cost/Share $2.20 Unrealized @ Report Date -4.0%

ADMA ADMA BIOLOGICS INC 6.4%

Value $13.86M Shares 7,000,000 Share Price $1.98 Est. Cost/Share $1.31 Unrealized @ Report Date +49.7%

— AMARIN CORP PLC -ADR 6.1%

Value $13.19M Shares 8,853,763 Share Price $1.49 Est. Cost/Share $2.49 Unrealized @ Report Date —

QDEL QUIDELORTHO CORP 5.4%

Value $11.64M Shares 119,787 Share Price $97.18 * Est. Cost/Share $101.94 Unrealized @ Report Date 0.0%

RZLT REZOLUTE INC 4.5%

Value $9.696M Shares 3,001,926 Share Price $3.23 * Est. Cost/Share $3.95 Unrealized @ Report Date -15.9%

— OPTINOSE INC 4.5%

Value $9.576M Shares 2,616,515 Share Price $3.66 Est. Cost/Share $1.62 Unrealized @ Report Date —

URGN UROGEN PHARMA LTD 4.2%

Value $9.099M Shares 1,111,050 Share Price $8.19 * Est. Cost/Share $7.09 Unrealized @ Report Date -3.2%

LGND LIGAND PHARMACEUTICALS 4.2%

Value $8.944M Shares 100,244 Share Price $89.22 * Est. Cost/Share $68.37 Unrealized @ Report Date -17.0%

— AFFIMED NV 4.1%

Value $8.708M Shares 3,143,773 Share Price $2.77 Est. Cost/Share $2.77 Unrealized @ Report Date —

— APOLLO ENDOSURGERY INC 3.7%

Value $7.891M Shares 2,161,999 Share Price $3.65 Est. Cost/Share $5.27 Unrealized @ Report Date —

OVID OVID THERAPEUTICS INC 3.5%

Value $7.499M Shares 3,487,928 Share Price $2.15 * Est. Cost/Share $3.43 Unrealized @ Report Date -29.5%

XGN EXAGEN INC 3.4%

Value $7.235M Shares 1,260,387 Share Price $5.74 Est. Cost/Share $11.52 Unrealized @ Report Date -49.4%

CSTL CASTLE BIOSCIENCES INC 3.0%

Value $6.483M Shares 295,372 Share Price $21.95 * Est. Cost/Share $23.24 Unrealized @ Report Date 0.0%

— CONFORMIS INC 2.8%

Value $6.122M Shares 17,304,350 Share Price $0.35 Est. Cost/Share $0.75 Unrealized @ Report Date —

DMAC DIAMEDICA THERAPEUTICS INC 1.1%

Value $2.376M Shares 1,176,344 Share Price $2.02 * Est. Cost/Share $4.07 Unrealized @ Report Date -42.7%

— AERIE PHARMACEUTICALS INC 0.9%

Value $1.884M Shares 251,235 Share Price $7.50 Est. Cost/Share $8.10 Unrealized @ Report Date —

— OPIANT PHARMACEUTICALS INC 0.8%

Value $1.826M Shares 152,278 Share Price $11.99 Est. Cost/Share $11.99 Unrealized @ Report Date —

ATYR ATYR PHARMA INC 0.8%

Value $1.702M Shares 601,580 Share Price $2.83 * Est. Cost/Share $6.39 Unrealized @ Report Date -43.5%

— MARINUS PHARMACEUTICALS INC 0.5%

Value $1.173M Shares 242,327 Share Price $4.84 Est. Cost/Share $5.90 Unrealized @ Report Date —

XOMA XOMA CORP 0.5%

Value $1.023M Shares 45,910 Share Price $22.28 * Est. Cost/Share $20.30 Unrealized @ Report Date +1.1%

ANIP ANI PHARMACEUTICALS INC 0.4%

Value $854K Shares 28,800 Share Price $29.65 * Est. Cost/Share $41.63 Unrealized @ Report Date -30.7%

— SYNLOGIC INC 0.0%

Value $107K Shares 92,746 Share Price $1.15 Est. Cost/Share $3.01 Unrealized @ Report Date —

— CIDARA THERAPEUTICS INC 0.0%

Value $102K Shares 208,443 Share Price $0.49 Est. Cost/Share $1.47 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
—	AMRYT PHARMA PLC - SPNR ADR	6,298,348	$44.02M	20.5%	$6.99	$12.42	—	SPONSORED ADS	03217L106
—	CTI BIOPHARMA CORP	3,681,195	$21.98M	10.2%	$5.97	$2.49	—	COM	12648L601
XERS	XERIS BIOPHARMA HOLDINGS INC	11,647,417	$17.94M	8.3%	$1.54 *	$2.20	-4.0%	COM	98422E103
ADMA	ADMA BIOLOGICS INC	7,000,000	$13.86M	6.4%	$1.98	$1.31	+49.7%	COM	000899104
—	AMARIN CORP PLC -ADR	8,853,763	$13.19M	6.1%	$1.49	$2.49	—	SPONS ADR NEW	023111206
QDEL	QUIDELORTHO CORP	119,787	$11.64M	5.4%	$97.18 *	$101.94	0.0%	COM	219798105
RZLT	REZOLUTE INC	3,001,926	$9.696M	4.5%	$3.23 *	$3.95	-15.9%	COM NEW	76200L309
—	OPTINOSE INC	2,616,515	$9.576M	4.5%	$3.66	$1.62	—	COM	68404V100
URGN	UROGEN PHARMA LTD	1,111,050	$9.099M	4.2%	$8.19 *	$7.09	-3.2%	COM	M96088105
LGND	LIGAND PHARMACEUTICALS	100,244	$8.944M	4.2%	$89.22 *	$68.37	-17.0%	COM NEW	53220K504
—	AFFIMED NV	3,143,773	$8.708M	4.1%	$2.77	$2.77	—	COM	N01045108
—	APOLLO ENDOSURGERY INC	2,161,999	$7.891M	3.7%	$3.65	$5.27	—	COM	03767D108
OVID	OVID THERAPEUTICS INC	3,487,928	$7.499M	3.5%	$2.15 *	$3.43	-29.5%	COM	690469101
XGN	EXAGEN INC	1,260,387	$7.235M	3.4%	$5.74	$11.52	-49.4%	COM	30068X103
CSTL	CASTLE BIOSCIENCES INC	295,372	$6.483M	3.0%	$21.95 *	$23.24	0.0%	COM	14843C105
—	CONFORMIS INC	17,304,350	$6.122M	2.8%	$0.35	$0.75	—	COM	20717E101
DMAC	DIAMEDICA THERAPEUTICS INC	1,176,344	$2.376M	1.1%	$2.02 *	$4.07	-42.7%	COM NEW	25253X207
—	AERIE PHARMACEUTICALS INC	251,235	$1.884M	0.9%	$7.50	$8.10	—	COM	00771V108
—	OPIANT PHARMACEUTICALS INC	152,278	$1.826M	0.8%	$11.99	$11.99	—	COM	683750103
ATYR	ATYR PHARMA INC	601,580	$1.702M	0.8%	$2.83 *	$6.39	-43.5%	COM NEW	002120202
—	MARINUS PHARMACEUTICALS INC	242,327	$1.173M	0.5%	$4.84	$5.90	—	COM NEW	56854Q200
XOMA	XOMA CORP	45,910	$1.023M	0.5%	$22.28 *	$20.30	+1.1%	COM NEW	98419J206
ANIP	ANI PHARMACEUTICALS INC	28,800	$854K	0.4%	$29.65 *	$41.63	-30.7%	COM	00182C103
—	SYNLOGIC INC	92,746	$107K	0.0%	$1.15	$3.01	—	COM	87166L100
—	CIDARA THERAPEUTICS INC	208,443	$102K	0.0%	$0.49	$1.47	—	COM	171757107