Samsara BioCapital, LLC Diversified Active

Location: Palo Alto, CA

CIK: 0001744967 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 14, 2025

Total Value: $766M (100.0% shares, 0.0% debt)

Holdings (27)

MLYS MINERALYS THERAPEUTICS INC 31.0%

Value $237M Shares 6,263,151 Est. Cost $16.38 Unrealized +32.1%

SRRK SCHOLAR ROCK HLDG CORP 27.3%

Value $209M Shares 5,612,896 Est. Cost $9.37 Unrealized +273.2%

KLRS KALARIS THERAPEUTICS INC 8.6%

Value $66.17M Shares 11,448,081 Est. Cost $9.79 Unrealized -66.2%

SEPN SEPTERNA INC 7.7%

Value $59.24M Shares 3,149,128 Est. Cost $22.17 Unrealized -40.8%

NGNE NEUROGENE INC 3.9%

Value $29.76M Shares 1,717,127 Est. Cost $20.31 Unrealized -1.1%

ALMS ALUMIS INC 2.5%

Value $19.16M Shares 4,801,370 Est. Cost $9.76 Unrealized -57.8%

UPB UPSTREAM BIO INC 2.4%

Value $18.1M Shares 962,154 Est. Cost $22.33 Unrealized -30.4%

GOSS GOSSAMER BIO INC 2.1%

Value $16.12M Shares 6,130,268 Est. Cost $1.15 Unrealized +91.3%

LENZ LENZ THERAPEUTICS INC 2.1%

Value $15.98M Shares 343,012 Est. Cost $20.79 Unrealized +76.9%

AQST AQUESTIVE THERAPEUTICS INC 1.8%

Value $13.97M Shares 2,500,000 Est. Cost $4.32 Unrealized 0.0%

PVLA PALVELLA THERAPEUTICS INC NE 1.7%

Value $13.14M Shares 209,634 Est. Cost $15.71 Unrealized +183.9%

— AVADEL PHARMACEUTICALS PLC 1.3%

Value $10.31M Shares 675,504 Est. Cost $14.06 Unrealized —

VTVT VTV THERAPEUTICS INC 1.1%

Value $8.744M Shares 374,461 Est. Cost $14.92 Unrealized +16.0%

NKTX NKARTA INC 1.0%

Value $7.8M Shares 3,768,035 Est. Cost $21.30 Unrealized -90.4%

CTNM CONTINEUM THERAPEUTICS INC 0.9%

Value $6.711M Shares 571,142 Est. Cost $16.10 Unrealized -49.9%

ACLX ARCELLX INC 0.9%

Value $6.664M Shares 81,165 Est. Cost $16.49 Unrealized +336.6%

ABVX ABIVAX SA 0.8%

Value $6.405M Shares 75,442 Est. Cost $84.90 Unrealized —

JBIO JADE BIOSCIENCES INC 0.6%

Value $4.584M Shares 531,163 Est. Cost $33.31 Unrealized -75.5%

AURA AURA BIOSCIENCES INC 0.5%

Value $3.614M Shares 584,849 Est. Cost $5.85 Unrealized +11.8%

ZYME ZYMEWORKS INC 0.5%

Value $3.551M Shares 207,901 Est. Cost $8.72 Unrealized +64.1%

SRZN SURROZEN INC 0.4%

Value $3.11M Shares 241,400 Est. Cost $11.62 Unrealized -9.8%

RYTM RHYTHM PHARMACEUTICALS INC 0.4%

Value $3.058M Shares 30,285 Est. Cost $17.86 Unrealized +419.9%

— SUTRO BIOPHARMA INC 0.2%

Value $1.908M Shares 2,196,814 Est. Cost $7.26 Unrealized —

TERN TERNS PHARMACEUTICALS INC 0.1%

Value $1.018M Shares 135,573 Est. Cost $21.92 Unrealized -70.9%

BOLT BOLT BIOTHERAPEUTICS INC 0.0%

Value $260K Shares 48,830 Est. Cost $6.62 Unrealized -16.2%

— NUVATION BIO INC 0.0%

Value $26,947 Shares 133,333 Est. Cost $0.28 Unrealized —

SRZNW SURROZEN INC 0.0%

Value $1,780 Shares 99,999 Est. Cost $0.19 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
MLYS	MINERALYS THERAPEUTICS INC	6,263,151	$237M	31.0%	$16.38	+32.1%	COM	603170101
SRRK	SCHOLAR ROCK HLDG CORP	5,612,896	$209M	27.3%	$9.37	+273.2%	COM	80706P103
KLRS	KALARIS THERAPEUTICS INC	11,448,081	$66.17M	8.6%	$9.79	-66.2%	COM	482929106
SEPN	SEPTERNA INC	3,149,128	$59.24M	7.7%	$22.17	-40.8%	COM	81734D104
NGNE	NEUROGENE INC	1,717,127	$29.76M	3.9%	$20.31	-1.1%	COM	64135M105
ALMS	ALUMIS INC	4,801,370	$19.16M	2.5%	$9.76	-57.8%	COM	022307102
UPB	UPSTREAM BIO INC	962,154	$18.1M	2.4%	$22.33	-30.4%	COM	91678A107
GOSS	GOSSAMER BIO INC	6,130,268	$16.12M	2.1%	$1.15	+91.3%	COM	38341P102
LENZ	LENZ THERAPEUTICS INC	343,012	$15.98M	2.1%	$20.79	+76.9%	COM	52635N103
AQST	AQUESTIVE THERAPEUTICS INC	2,500,000	$13.97M	1.8%	$4.32	0.0%	COM	03843E104
PVLA	PALVELLA THERAPEUTICS INC NE	209,634	$13.14M	1.7%	$15.71	+183.9%	COM	697947109
—	AVADEL PHARMACEUTICALS PLC	675,504	$10.31M	1.3%	$14.06	—	COM SHS	G29687103
VTVT	VTV THERAPEUTICS INC	374,461	$8.744M	1.1%	$14.92	+16.0%	CL A NEW	918385204
NKTX	NKARTA INC	3,768,035	$7.8M	1.0%	$21.30	-90.4%	COM	65487U108
CTNM	CONTINEUM THERAPEUTICS INC	571,142	$6.711M	0.9%	$16.10	-49.9%	CL A	21217B100
ACLX	ARCELLX INC	81,165	$6.664M	0.9%	$16.49	+336.6%	COMMON STOCK	03940C100
ABVX	ABIVAX SA	75,442	$6.405M	0.8%	$84.90	—	SPONSORED ADS	00370M103
JBIO	JADE BIOSCIENCES INC	531,163	$4.584M	0.6%	$33.31	-75.5%	COM NEW	008064206
AURA	AURA BIOSCIENCES INC	584,849	$3.614M	0.5%	$5.85	+11.8%	COM	05153U107
ZYME	ZYMEWORKS INC	207,901	$3.551M	0.5%	$8.72	+64.1%	COM	98985Y108
SRZN	SURROZEN INC	241,400	$3.11M	0.4%	$11.62	-9.8%	COM NEW	86889P208
RYTM	RHYTHM PHARMACEUTICALS INC	30,285	$3.058M	0.4%	$17.86	+419.9%	COM	76243J105
—	SUTRO BIOPHARMA INC	2,196,814	$1.908M	0.2%	$7.26	—	COM	869367102
TERN	TERNS PHARMACEUTICALS INC	135,573	$1.018M	0.1%	$21.92	-70.9%	COM	880881107
BOLT	BOLT BIOTHERAPEUTICS INC	48,830	$260K	0.0%	$6.62	-16.2%	COM NEW	097702203
—	NUVATION BIO INC	133,333	$26,947	0.0%	$0.28	—	*W EXP 02/10/202	67080N119
SRZNW	SURROZEN INC	99,999	$1,780	0.0%	$0.19	—	*W EXP 08/01/203	86889P117