Samsara BioCapital, LLC Diversified Active

Name: Samsara BioCapital, LLC Q1 2026 13F Filing | 13F Explorer
Creator: Samsara BioCapital, LLC
Published: 2026-05-15

Location: PALO ALTO, CA

CIK: 0001744967 · Show all filings

Period: Q1 2026 (← Previous)

Filing Date: May 15, 2026

Total Value: $1.029B (100.0% shares, 0.0% debt)

Holdings (22)

New Positions (3)

SGP SPYGLASS PHARMA INC 5.3%

Value $54.67M Shares 2,109,953 Est. Cost — Unrealized —

AGMB AGOMAB THERAPEUTICS NV 0.6%

Value $6.294M Shares 600,000 Est. Cost — Unrealized —

CHRS COHERUS ONCOLOGY INC 0.6%

Value $5.794M Shares 3,428,571 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SGP	SPYGLASS PHARMA INC	2,109,953	$54.67M	5.3%	—	—	COM SHS	85220G109
AGMB	AGOMAB THERAPEUTICS NV	600,000	$6.294M	0.6%	—	—	SPONSORED ADS	00860C102
CHRS	COHERUS ONCOLOGY INC	3,428,571	$5.794M	0.6%	—	—	COM	19249H103

Increased Positions (2)

ALMS ALUMIS INC 13.6%

Value $140M (+148.8%) Shares 6,345,219 (+10.2%) Est. Cost — Unrealized —

STRO SUTRO BIOPHARMA INC 2.6%

Value $26.48M (+1019.0%) Shares 1,062,872 (+419.7%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ALMS	ALUMIS INC	6,345,219 (+10.2%)	$140M (+148.8%)	13.6%	—	—	COM	022307102
STRO	SUTRO BIOPHARMA INC	1,062,872 (+419.7%)	$26.48M (+1019.0%)	2.6%	—	—	COM SHS	869367201

Exited Positions (2)

CTNM CONTINEUM THERAPEUTICS INC 0.1%

Value $826K Shares 72,245 Est. Cost — Unrealized —

— NUVATION BIO INC 0.0%

Value $40,959 Shares 124,119 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
CTNM	CONTINEUM THERAPEUTICS INC	72,245	$826K	0.1%	—	—	—	21217B100
—	NUVATION BIO INC	124,119	$40,959	0.0%	—	—	—	67080N119

Decreased Positions (3)

PVLA PALVELLA THERAPEUTICS INC NE 0.5%

Value $4.791M (-56.3%) Shares 38,432 (-63.3%) Est. Cost — Unrealized —

ABVX ABIVAX SA 0.6%

Value $6.3M (-38.1%) Shares 56,581 (-25.0%) Est. Cost — Unrealized —

XFOR X4 PHARMACEUTICALS INC 0.7%

Value $7.568M (-3.5%) Shares 1,832,566 (-6.5%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
PVLA	PALVELLA THERAPEUTICS INC NE	38,432 (-63.3%)	$4.791M (-56.3%)	0.5%	—	—	COM	697947109
ABVX	ABIVAX SA	56,581 (-25.0%)	$6.3M (-38.1%)	0.6%	—	—	SPONSORED ADS	00370M103
XFOR	X4 PHARMACEUTICALS INC	1,832,566 (-6.5%)	$7.568M (-3.5%)	0.7%	—	—	COM NEW	98420X202

Unchanged Positions (14)

MLYS MINERALYS THERAPEUTICS INC 15.5%

Value $159M Shares 5,871,018 Est. Cost — Unrealized —

SRRK SCHOLAR ROCK HLDG CORP 32.9%

Value $339M Shares 6,897,652 Est. Cost — Unrealized —

KLRS KALARIS THERAPEUTICS INC 7.3%

Value $74.71M Shares 12,948,081 Est. Cost — Unrealized —

GOSS GOSSAMER BIO INC 0.2%

Value $2.373M Shares 7,222,559 Est. Cost — Unrealized —

UPB UPSTREAM BIO INC 0.6%

Value $6.624M Shares 736,047 Est. Cost — Unrealized —

SEPN SEPTERNA INC 7.4%

Value $75.67M Shares 3,149,128 Est. Cost — Unrealized —

AQST AQUESTIVE THERAPEUTICS INC 1.0%

Value $10.38M Shares 2,500,000 Est. Cost — Unrealized —

RANI RANI THERAPEUTICS HLDGS INC 0.6%

Value $6.246M Shares 8,500,000 Est. Cost — Unrealized —

IVA INVENTIVA SA 2.8%

Value $28.83M Shares 5,194,805 Est. Cost — Unrealized —

ACLX ARCELLX INC 0.7%

Value $6.989M Shares 60,873 Est. Cost — Unrealized —

JBIO JADE BIOSCIENCES INC 1.3%

Value $13.61M Shares 968,798 Est. Cost — Unrealized —

NKTX NKARTA INC 0.7%

Value $7.401M Shares 3,507,666 Est. Cost — Unrealized —

NGNE NEUROGENE INC 3.4%

Value $34.62M Shares 1,717,127 Est. Cost — Unrealized —

VTVT VTV THERAPEUTICS INC 1.2%

Value $11.84M Shares 298,496 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
MLYS	MINERALYS THERAPEUTICS INC	5,871,018	$159M	15.5%	—	—	COM	603170101
SRRK	SCHOLAR ROCK HLDG CORP	6,897,652	$339M	32.9%	—	—	COM	80706P103
KLRS	KALARIS THERAPEUTICS INC	12,948,081	$74.71M	7.3%	—	—	COM	482929106
GOSS	GOSSAMER BIO INC	7,222,559	$2.373M	0.2%	—	—	COM	38341P102
UPB	UPSTREAM BIO INC	736,047	$6.624M	0.6%	—	—	COM	91678A107
SEPN	SEPTERNA INC	3,149,128	$75.67M	7.4%	—	—	COM	81734D104
AQST	AQUESTIVE THERAPEUTICS INC	2,500,000	$10.38M	1.0%	—	—	COM	03843E104
RANI	RANI THERAPEUTICS HLDGS INC	8,500,000	$6.246M	0.6%	—	—	COM CL A	753018100
IVA	INVENTIVA SA	5,194,805	$28.83M	2.8%	—	—	ADS	46124U107
ACLX	ARCELLX INC	60,873	$6.989M	0.7%	—	—	COMMON STOCK	03940C100
JBIO	JADE BIOSCIENCES INC	968,798	$13.61M	1.3%	—	—	COM NEW	008064206
NKTX	NKARTA INC	3,507,666	$7.401M	0.7%	—	—	COM	65487U108
NGNE	NEUROGENE INC	1,717,127	$34.62M	3.4%	—	—	COM	64135M105
VTVT	VTV THERAPEUTICS INC	298,496	$11.84M	1.2%	—	—	CL A NEW	918385204