Samsara BioCapital, LLC Diversified Active

Name: Samsara BioCapital, LLC Q2 2026 13F Filing | 13F Explorer
Creator: Samsara BioCapital, LLC
Published: 2026-08-14

Location: Palo Alto, CA

CIK: 0001744967 · Show all filings

Period: Q2 2026 (← Previous)

Filing Date: Aug 14, 2026

Total Value: $1.217B (100.0% shares, 0.0% debt)

Holdings (24)

New Positions (4)

ALMR ALAMAR BIOSCIENCES INC 5.5%

Value $67.19M Shares 2,480,310 Est. Cost — Unrealized —

PBLS PARABILIS MEDICINES INC 1.3%

Value $15.22M Shares 556,044 Est. Cost — Unrealized —

ARTV ARTIVA BIOTHERAPEUTICS INC 0.8%

Value $9.262M Shares 954,861 Est. Cost — Unrealized —

ELOX ELOXX PHARMACEUTICALS INC 0.5%

Value $5.552M Shares 400,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ALMR	ALAMAR BIOSCIENCES INC	2,480,310	$67.19M	5.5%	—	—	COMMON STOCK	010911105
PBLS	PARABILIS MEDICINES INC	556,044	$15.22M	1.3%	—	—	COM	698955101
ARTV	ARTIVA BIOTHERAPEUTICS INC	954,861	$9.262M	0.8%	—	—	COM	04317A107
ELOX	ELOXX PHARMACEUTICALS INC	400,000	$5.552M	0.5%	—	—	COM NEW	29014R301

Increased Positions (2)

IVA INVENTIVA SA 2.0%

Value $23.87M (-17.2%) Shares 6,314,805 (+21.6%) Est. Cost — Unrealized —

RANI RANI THERAPEUTICS HLDGS INC 0.6%

Value $7.885M (+26.2%) Shares 10,369,159 (+22.0%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
IVA	INVENTIVA SA	6,314,805 (+21.6%)	$23.87M (-17.2%)	2.0%	—	—	ADS	46124U107
RANI	RANI THERAPEUTICS HLDGS INC	10,369,159 (+22.0%)	$7.885M (+26.2%)	0.6%	—	—	COM CL A	753018100

Exited Positions (2)

ACLX ARCELLX INC 0.6%

Value $6.989M Shares 60,873 Est. Cost — Unrealized —

PVLA PALVELLA THERAPEUTICS INC NE 0.4%

Value $4.791M Shares 38,432 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ACLX	ARCELLX INC	60,873	$6.989M	0.6%	—	—	—	03940C100
PVLA	PALVELLA THERAPEUTICS INC NE	38,432	$4.791M	0.4%	—	—	—	697947109

Decreased Positions (4)

UPB UPSTREAM BIO INC 0.2%

Value $2.448M (-63.1%) Shares 353,717 (-51.9%) Est. Cost — Unrealized —

JBIO JADE BIOSCIENCES INC 1.3%

Value $16.36M (+20.2%) Shares 736,237 (-24.0%) Est. Cost — Unrealized —

XFOR X4 PHARMACEUTICALS INC 0.5%

Value $6.517M (-13.9%) Shares 1,395,587 (-23.8%) Est. Cost — Unrealized —

ABVX ABIVAX SA 0.6%

Value $7.342M (+16.5%) Shares 55,095 (-2.6%) Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
UPB	UPSTREAM BIO INC	353,717 (-51.9%)	$2.448M (-63.1%)	0.2%	—	—	COM	91678A107
JBIO	JADE BIOSCIENCES INC	736,237 (-24.0%)	$16.36M (+20.2%)	1.3%	—	—	COM NEW	008064206
XFOR	X4 PHARMACEUTICALS INC	1,395,587 (-23.8%)	$6.517M (-13.9%)	0.5%	—	—	COM NEW	98420X202
ABVX	ABIVAX SA	55,095 (-2.6%)	$7.342M (+16.5%)	0.6%	—	—	SPONSORED ADS	00370M103

Unchanged Positions (14)

SRRK SCHOLAR ROCK HLDG CORP 31.2%

Value $379M Shares 6,897,652 Est. Cost — Unrealized —

ALMS ALUMIS INC 14.7%

Value $179M Shares 6,345,219 Est. Cost — Unrealized —

SEPN SEPTERNA INC 8.7%

Value $105M Shares 3,149,128 Est. Cost — Unrealized —

KLRS KALARIS THERAPEUTICS INC 4.3%

Value $52.43M Shares 12,881,175 Est. Cost — Unrealized —

NGNE NEUROGENE INC 4.4%

Value $54M Shares 1,717,127 Est. Cost — Unrealized —

STRO SUTRO BIOPHARMA INC 2.9%

Value $35.29M Shares 1,062,872 Est. Cost — Unrealized —

SGP SPYGLASS PHARMA INC 3.9%

Value $46.97M Shares 2,109,953 Est. Cost — Unrealized —

NKTX NKARTA INC 0.8%

Value $9.927M Shares 3,507,666 Est. Cost — Unrealized —

AGMB AGOMAB THERAPEUTICS NV 0.6%

Value $7.788M Shares 600,000 Est. Cost — Unrealized —

GOSS GOSSAMER BIO INC 0.1%

Value $1.189M Shares 7,222,559 Est. Cost — Unrealized —

CHRS COHERUS ONCOLOGY INC 0.4%

Value $4.8M Shares 3,428,571 Est. Cost — Unrealized —

MLYS MINERALYS THERAPEUTICS INC 13.0%

Value $158M Shares 5,871,018 Est. Cost — Unrealized —

VTVT VTV THERAPEUTICS INC 0.9%

Value $11.24M Shares 298,496 Est. Cost — Unrealized —

AQST AQUESTIVE THERAPEUTICS INC 0.9%

Value $10.4M Shares 2,500,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SRRK	SCHOLAR ROCK HLDG CORP	6,897,652	$379M	31.2%	—	—	COM	80706P103
ALMS	ALUMIS INC	6,345,219	$179M	14.7%	—	—	COM	022307102
SEPN	SEPTERNA INC	3,149,128	$105M	8.7%	—	—	COM	81734D104
KLRS	KALARIS THERAPEUTICS INC	12,881,175	$52.43M	4.3%	—	—	COM	482929106
NGNE	NEUROGENE INC	1,717,127	$54M	4.4%	—	—	COM	64135M105
STRO	SUTRO BIOPHARMA INC	1,062,872	$35.29M	2.9%	—	—	COM SHS	869367201
SGP	SPYGLASS PHARMA INC	2,109,953	$46.97M	3.9%	—	—	COM SHS	85220G109
NKTX	NKARTA INC	3,507,666	$9.927M	0.8%	—	—	COM	65487U108
AGMB	AGOMAB THERAPEUTICS NV	600,000	$7.788M	0.6%	—	—	SPONSORED ADS	00860C102
GOSS	GOSSAMER BIO INC	7,222,559	$1.189M	0.1%	—	—	COM	38341P102
CHRS	COHERUS ONCOLOGY INC	3,428,571	$4.8M	0.4%	—	—	COM	19249H103
MLYS	MINERALYS THERAPEUTICS INC	5,871,018	$158M	13.0%	—	—	COM	603170101
VTVT	VTV THERAPEUTICS INC	298,496	$11.24M	0.9%	—	—	CL A NEW	918385204
AQST	AQUESTIVE THERAPEUTICS INC	2,500,000	$10.4M	0.9%	—	—	COM	03843E104