Octagon Capital Advisors LP Quant / Systematic

Location: New York, NY

CIK: 0001839435 · Show all filings

Period: Q3 2024 (← Previous) (Next →)

Filing Date: Nov 14, 2024

Total Value: $643M (100.0% shares, 0.0% debt)

Holdings (42)

APLS APELLIS PHARMACEUTICALS INC 13.5%

Value $86.72M Shares 3,006,980 Est. Cost $47.09 Unrealized -21.4%

— VERONA PHARMA PLC 8.2%

Value $52.8M Shares 1,835,200 Est. Cost $17.59 Unrealized —

GPCR STRUCTURE THERAPEUTICS INC 8.2%

Value $52.58M Shares 1,198,000 Est. Cost $40.29 Unrealized —

DNTH DIANTHUS THERAPEUTICS INC 7.4%

Value $47.82M Shares 1,746,667 Est. Cost $19.26 Unrealized +44.6%

AVBP ARRIVENT BIOPHARMA INC 7.2%

Value $46.45M Shares 1,976,387 Est. Cost $20.39 Unrealized +11.3%

CNTA CENTESSA PHARMACEUTICALS PLC 5.0%

Value $32.17M Shares 2,012,052 Est. Cost $7.34 Unrealized —

INSM INSMED INC 5.0%

Value $31.89M Shares 436,820 Est. Cost $21.76 Unrealized +239.2%

NUVB NUVATION BIO INC 4.3%

Value $27.87M Shares 12,171,513 Est. Cost $2.99 Unrealized +1.9%

CRBP CORBUS PHARMACEUTICALS HLDGS 3.6%

Value $23M Shares 1,115,000 Est. Cost $40.87 Unrealized +25.2%

OCUL OCULAR THERAPEUTIX INC 3.3%

Value $21.1M Shares 2,425,000 Est. Cost $7.10 Unrealized +16.1%

VRDN VIRIDIAN THERAPEUTICS INC 3.1%

Value $19.79M Shares 870,000 Est. Cost $22.43 Unrealized -27.1%

CATX PERSPECTIVE THERAPEUTICS INC 3.0%

Value $18.99M Shares 1,422,224 Est. Cost $14.46 Unrealized -8.0%

INSM INSMED INC 2.8%

Value $18.25M Shares 250,000 Est. Cost $21.76 Unrealized +239.2%

— MIND MEDICINE MINDMED INC 2.7%

Value $17.17M Shares 3,018,000 Est. Cost $8.34 Unrealized —

COGT COGENT BIOSCIENCES INC 2.2%

Value $14.09M Shares 1,305,000 Est. Cost $9.74 Unrealized 0.0%

BBIO BRIDGEBIO PHARMA INC 2.2%

Value $14.05M Shares 552,000 Est. Cost $30.51 Unrealized -13.9%

PHVS PHARVARIS N V 1.8%

Value $11.49M Shares 620,470 Est. Cost $18.27 Unrealized 0.0%

DYN DYNE THERAPEUTICS INC 1.5%

Value $9.437M Shares 262,726 Est. Cost $16.21 Unrealized +145.5%

TSHA TAYSHA GENE THERAPIES INC 1.4%

Value $9.19M Shares 4,572,222 Est. Cost $2.36 Unrealized -7.1%

GOSS GOSSAMER BIO INC 1.4%

Value $9.063M Shares 9,187,883 Est. Cost $2.93 Unrealized -67.1%

— ALLOVIR INC 1.4%

Value $9.057M Shares 11,202,000 Est. Cost $0.75 Unrealized —

EYPT EYEPOINT PHARMACEUTICALS INC 1.4%

Value $8.737M Shares 1,093,503 Est. Cost $24.76 Unrealized -64.5%

PRAX PRAXIS PRECISION MEDICINES I 1.2%

Value $7.48M Shares 130,000 Est. Cost $44.86 Unrealized +20.4%

MLYS MINERALYS THERAPEUTICS INC 1.1%

Value $7.266M Shares 600,000 Est. Cost $12.37 Unrealized -2.1%

— REGULUS THERAPEUTICS INC 1.0%

Value $6.694M Shares 4,263,701 Est. Cost $1.78 Unrealized —

VTYX VENTYX BIOSCIENCES INC 0.8%

Value $5.213M Shares 2,391,114 Est. Cost $4.42 Unrealized -47.9%

TNYA TENAYA THERAPEUTICS INC 0.8%

Value $4.972M Shares 2,576,200 Est. Cost $4.78 Unrealized -41.0%

HELP CYBIN INC 0.7%

Value $4.353M Shares 489,596 Est. Cost $9.89 Unrealized 0.0%

— RENEO PHARMACEUTICALS INC 0.6%

Value $3.825M Shares 2,250,000 Est. Cost $6.46 Unrealized —

— UNICYCIVE THERAPEUTICS INC 0.5%

Value $3.491M Shares 8,559,000 Est. Cost $0.41 Unrealized —

PEPG PEPGEN INC 0.5%

Value $3.216M Shares 376,117 Est. Cost $11.81 Unrealized +0.2%

BBOT HELIX ACQUISITION CORP II 0.4%

Value $2.612M Shares 250,000 Est. Cost $10.35 Unrealized +0.1%

BDTX BLACK DIAMOND THERAPEUTICS I 0.4%

Value $2.584M Shares 594,000 Est. Cost $5.44 Unrealized 0.0%

ANNX ANNEXON INC 0.4%

Value $2.368M Shares 400,000 Est. Cost $4.77 Unrealized +24.3%

— MERSANA THERAPEUTICS INC 0.3%

Value $1.875M Shares 992,000 Est. Cost $4.48 Unrealized —

IPSC CENTURY THERAPEUTICS INC 0.2%

Value $1.14M Shares 666,825 Est. Cost $3.59 Unrealized -45.5%

— AEROVATE THERAPEUTICS INC 0.2%

Value $973K Shares 465,440 Est. Cost $25.63 Unrealized —

— NUVATION BIO INC 0.1%

Value $715K Shares 312,336 Est. Cost $2.29 Unrealized —

AUTL AUTOLUS THERAPEUTICS PLC 0.1%

Value $639K Shares 176,000 Est. Cost $6.38 Unrealized —

NGNE NEUROGENE INC 0.1%

Value $629K Shares 15,000 Est. Cost $38.78 Unrealized 0.0%

— RAPT THERAPEUTICS INC 0.1%

Value $587K Shares 292,000 Est. Cost $24.85 Unrealized —

NKTX NKARTA INC 0.1%

Value $542K Shares 120,000 Est. Cost $10.40 Unrealized -45.4%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
APLS	APELLIS PHARMACEUTICALS INC	3,006,980	$86.72M	13.5%	$47.09	-21.4%	COM	03753U106
—	VERONA PHARMA PLC	1,835,200	$52.8M	8.2%	$17.59	—	SPONSORED ADS	925050106
GPCR	STRUCTURE THERAPEUTICS INC	1,198,000	$52.58M	8.2%	$40.29	—	SPONSORED ADS	86366E106
DNTH	DIANTHUS THERAPEUTICS INC	1,746,667	$47.82M	7.4%	$19.26	+44.6%	COM	252828108
AVBP	ARRIVENT BIOPHARMA INC	1,976,387	$46.45M	7.2%	$20.39	+11.3%	COM	04272N102
CNTA	CENTESSA PHARMACEUTICALS PLC	2,012,052	$32.17M	5.0%	$7.34	—	SPONSORED ADS	152309100
INSM	INSMED INC	436,820	$31.89M	5.0%	$21.76	+239.2%	COM PAR $.01	457669307
NUVB	NUVATION BIO INC	12,171,513	$27.87M	4.3%	$2.99	+1.9%	COM CL A	67080N101
CRBP	CORBUS PHARMACEUTICALS HLDGS	1,115,000	$23M	3.6%	$40.87	+25.2%	COM NEW	21833P301
OCUL	OCULAR THERAPEUTIX INC	2,425,000	$21.1M	3.3%	$7.10	+16.1%	COM	67576A100
VRDN	VIRIDIAN THERAPEUTICS INC	870,000	$19.79M	3.1%	$22.43	-27.1%	COM	92790C104
CATX	PERSPECTIVE THERAPEUTICS INC	1,422,224	$18.99M	3.0%	$14.46	-8.0%	COM NEW	46489V302
INSM	INSMED INC	250,000	$18.25M	2.8%	$21.76	+239.2%	Call	457669307
—	MIND MEDICINE MINDMED INC	3,018,000	$17.17M	2.7%	$8.34	—	COM NEW	60255C885
COGT	COGENT BIOSCIENCES INC	1,305,000	$14.09M	2.2%	$9.74	0.0%	COM	19240Q201
BBIO	BRIDGEBIO PHARMA INC	552,000	$14.05M	2.2%	$30.51	-13.9%	COM	10806X102
PHVS	PHARVARIS N V	620,470	$11.49M	1.8%	$18.27	0.0%	COM	N69605108
DYN	DYNE THERAPEUTICS INC	262,726	$9.437M	1.5%	$16.21	+145.5%	COM	26818M108
TSHA	TAYSHA GENE THERAPIES INC	4,572,222	$9.19M	1.4%	$2.36	-7.1%	COM SHS	877619106
GOSS	GOSSAMER BIO INC	9,187,883	$9.063M	1.4%	$2.93	-67.1%	COM	38341P102
—	ALLOVIR INC	11,202,000	$9.057M	1.4%	$0.75	—	COM	019818103
EYPT	EYEPOINT PHARMACEUTICALS INC	1,093,503	$8.737M	1.4%	$24.76	-64.5%	COM NEW	30233G209
PRAX	PRAXIS PRECISION MEDICINES I	130,000	$7.48M	1.2%	$44.86	+20.4%	COM NEW	74006W207
MLYS	MINERALYS THERAPEUTICS INC	600,000	$7.266M	1.1%	$12.37	-2.1%	COM	603170101
—	REGULUS THERAPEUTICS INC	4,263,701	$6.694M	1.0%	$1.78	—	COM	75915K309
VTYX	VENTYX BIOSCIENCES INC	2,391,114	$5.213M	0.8%	$4.42	-47.9%	COM	92332V107
TNYA	TENAYA THERAPEUTICS INC	2,576,200	$4.972M	0.8%	$4.78	-41.0%	COM	87990A106
HELP	CYBIN INC	489,596	$4.353M	0.7%	$9.89	0.0%	COM	23256X407
—	RENEO PHARMACEUTICALS INC	2,250,000	$3.825M	0.6%	$6.46	—	COM	75974E103
—	UNICYCIVE THERAPEUTICS INC	8,559,000	$3.491M	0.5%	$0.41	—	COM	90466Y103
PEPG	PEPGEN INC	376,117	$3.216M	0.5%	$11.81	+0.2%	COM	713317105
BBOT	HELIX ACQUISITION CORP II	250,000	$2.612M	0.4%	$10.35	+0.1%	CL A ORD SHS	G4444H101
BDTX	BLACK DIAMOND THERAPEUTICS I	594,000	$2.584M	0.4%	$5.44	0.0%	COM	09203E105
ANNX	ANNEXON INC	400,000	$2.368M	0.4%	$4.77	+24.3%	COM	03589W102
—	MERSANA THERAPEUTICS INC	992,000	$1.875M	0.3%	$4.48	—	COM	59045L106
IPSC	CENTURY THERAPEUTICS INC	666,825	$1.14M	0.2%	$3.59	-45.5%	COM	15673T100
—	AEROVATE THERAPEUTICS INC	465,440	$973K	0.2%	$25.63	—	COM	008064107
—	NUVATION BIO INC	312,336	$715K	0.1%	$2.29	—	*W EXP 07/07/202	67080N119
AUTL	AUTOLUS THERAPEUTICS PLC	176,000	$639K	0.1%	$6.38	—	SPON ADS	05280R100
NGNE	NEUROGENE INC	15,000	$629K	0.1%	$38.78	0.0%	COM	64135M105
—	RAPT THERAPEUTICS INC	292,000	$587K	0.1%	$24.85	—	COM	75382E109
NKTX	NKARTA INC	120,000	$542K	0.1%	$10.40	-45.4%	COM	65487U108