Octagon Capital Advisors LP Quant / Systematic

CIK: 0001839435 · Show all filings

Period: Q4 2024 (← Previous) (Next →)

Filing Date: Feb 14, 2025

Total Value ($000): $607,701 (100.0% shares, 0.0% debt)

Holdings (33)

APLS APELLIS PHARMACEUTICALS INC 15.8%

Value ($000) $95,953 Shares 3,006,980 Est. Cost $47.09 Unrealized -36.1%

AVBP ARRIVENT BIOPHARMA INC 9.0%

Value ($000) $54,862 Shares 2,059,387 Est. Cost $20.73 Unrealized +38.5%

DNTH DIANTHUS THERAPEUTICS INC 7.6%

Value ($000) $46,002 Shares 2,110,167 Est. Cost $20.37 Unrealized +26.2%

CNTA CENTESSA PHARMACEUTICALS PLC 5.5%

Value ($000) $33,384 Shares 1,993,052 Est. Cost $7.34 Unrealized —

— VERONA PHARMA PLC 4.4%

Value ($000) $26,530 Shares 571,264 Est. Cost $17.59 Unrealized —

NUVB NUVATION BIO INC 4.0%

Value ($000) $24,480 Shares 9,202,907 Est. Cost $2.99 Unrealized -14.0%

INSM INSMED INC 3.8%

Value ($000) $22,921 Shares 332,000 Est. Cost $21.76 Unrealized +231.0%

COGT COGENT BIOSCIENCES INC 3.5%

Value ($000) $21,551 Shares 2,763,000 Est. Cost $9.86 Unrealized +1.1%

SRRK SCHOLAR ROCK HLDG CORP 3.5%

Value ($000) $21,091 Shares 488,000 Est. Cost $32.56 Unrealized 0.0%

— MIND MEDICINE MINDMED INC 3.5%

Value ($000) $21,005 Shares 3,018,000 Est. Cost $8.34 Unrealized —

OCUL OCULAR THERAPEUTIX INC 3.4%

Value ($000) $20,710 Shares 2,425,000 Est. Cost $7.10 Unrealized +37.5%

TSHA TAYSHA GENE THERAPIES INC 3.0%

Value ($000) $18,079 Shares 10,450,000 Est. Cost $2.20 Unrealized -5.7%

INSM INSMED INC 2.8%

Value ($000) $17,260 Shares 250,000 Est. Cost $21.76 Unrealized +231.0%

VRDN VIRIDIAN THERAPEUTICS INC 2.7%

Value ($000) $16,678 Shares 870,000 Est. Cost $22.43 Unrealized -3.1%

GOSS GOSSAMER BIO INC 2.7%

Value ($000) $16,599 Shares 18,350,000 Est. Cost $1.89 Unrealized -54.8%

DYN DYNE THERAPEUTICS INC 2.6%

Value ($000) $15,738 Shares 668,000 Est. Cost $24.32 Unrealized +21.6%

PHVS PHARVARIS N V 2.5%

Value ($000) $14,914 Shares 778,000 Est. Cost $18.74 Unrealized +9.8%

CRBP CORBUS PHARMACEUTICALS HLDGS 2.2%

Value ($000) $13,157 Shares 1,115,000 Est. Cost $40.87 Unrealized -59.0%

— MERUS N V 2.1%

Value ($000) $12,951 Shares 308,000 Est. Cost $42.05 Unrealized —

ERAS ERASCA INC 2.1%

Value ($000) $12,893 Shares 5,136,795 Est. Cost $2.74 Unrealized 0.0%

BBIO BRIDGEBIO PHARMA INC 2.0%

Value ($000) $12,118 Shares 441,600 Est. Cost $30.51 Unrealized -15.3%

SNDX SYNDAX PHARMACEUTICALS INC 2.0%

Value ($000) $11,951 Shares 904,000 Est. Cost $17.11 Unrealized 0.0%

KALV KALVISTA PHARMACEUTICALS INC 1.9%

Value ($000) $11,604 Shares 1,370,000 Est. Cost $10.36 Unrealized 0.0%

— UNICYCIVE THERAPEUTICS INC 1.3%

Value ($000) $7,942 Shares 10,000,000 Est. Cost $0.46 Unrealized —

— REGULUS THERAPEUTICS INC 1.3%

Value ($000) $7,661 Shares 4,848,802 Est. Cost $1.76 Unrealized —

CATX PERSPECTIVE THERAPEUTICS INC 1.2%

Value ($000) $7,352 Shares 2,304,752 Est. Cost $12.05 Unrealized -32.2%

NGNE NEUROGENE INC 1.1%

Value ($000) $6,927 Shares 303,000 Est. Cost $37.29 Unrealized -0.2%

— ALLOVIR INC 0.8%

Value ($000) $4,710 Shares 11,215,000 Est. Cost $0.42 Unrealized —

ATYR ATYR PHARMA INC 0.5%

Value ($000) $3,258 Shares 900,000 Est. Cost $3.03 Unrealized 0.0%

BBOT HELIX ACQUISITION CORP II 0.4%

Value ($000) $2,625 Shares 250,000 Est. Cost $10.35 Unrealized +1.5%

CNTA CENTESSA PHARMACEUTICALS PLC 0.4%

Value ($000) $2,546 Shares 152,000 Est. Cost $7.34 Unrealized —

— MERSANA THERAPEUTICS INC 0.2%

Value ($000) $1,419 Shares 992,000 Est. Cost $4.48 Unrealized —

— NUVATION BIO INC 0.1%

Value ($000) $831 Shares 312,336 Est. Cost $2.29 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
APLS	APELLIS PHARMACEUTICALS INC	3,006,980	$95,953	15.8%	$47.09	-36.1%	COM	03753U106
AVBP	ARRIVENT BIOPHARMA INC	2,059,387	$54,862	9.0%	$20.73	+38.5%	COM	04272N102
DNTH	DIANTHUS THERAPEUTICS INC	2,110,167	$46,002	7.6%	$20.37	+26.2%	COM	252828108
CNTA	CENTESSA PHARMACEUTICALS PLC	1,993,052	$33,384	5.5%	$7.34	—	SPONSORED ADS	152309100
—	VERONA PHARMA PLC	571,264	$26,530	4.4%	$17.59	—	SPONSORED ADS	925050106
NUVB	NUVATION BIO INC	9,202,907	$24,480	4.0%	$2.99	-14.0%	COM CL A	67080N101
INSM	INSMED INC	332,000	$22,921	3.8%	$21.76	+231.0%	COM PAR	457669307
COGT	COGENT BIOSCIENCES INC	2,763,000	$21,551	3.5%	$9.86	+1.1%	COM	19240Q201
SRRK	SCHOLAR ROCK HLDG CORP	488,000	$21,091	3.5%	$32.56	0.0%	COM	80706P103
—	MIND MEDICINE MINDMED INC	3,018,000	$21,005	3.5%	$8.34	—	COM NEW	60255C885
OCUL	OCULAR THERAPEUTIX INC	2,425,000	$20,710	3.4%	$7.10	+37.5%	COM	67576A100
TSHA	TAYSHA GENE THERAPIES INC	10,450,000	$18,079	3.0%	$2.20	-5.7%	COM SHS	877619106
INSM	INSMED INC	250,000	$17,260	2.8%	$21.76	+231.0%	Call	457669307
VRDN	VIRIDIAN THERAPEUTICS INC	870,000	$16,678	2.7%	$22.43	-3.1%	COM	92790C104
GOSS	GOSSAMER BIO INC	18,350,000	$16,599	2.7%	$1.89	-54.8%	COM	38341P102
DYN	DYNE THERAPEUTICS INC	668,000	$15,738	2.6%	$24.32	+21.6%	COM	26818M108
PHVS	PHARVARIS N V	778,000	$14,914	2.5%	$18.74	+9.8%	COM	N69605108
CRBP	CORBUS PHARMACEUTICALS HLDGS	1,115,000	$13,157	2.2%	$40.87	-59.0%	COM NEW	21833P301
—	MERUS N V	308,000	$12,951	2.1%	$42.05	—	COM	N5749R100
ERAS	ERASCA INC	5,136,795	$12,893	2.1%	$2.74	0.0%	COM	29479A108
BBIO	BRIDGEBIO PHARMA INC	441,600	$12,118	2.0%	$30.51	-15.3%	COM	10806X102
SNDX	SYNDAX PHARMACEUTICALS INC	904,000	$11,951	2.0%	$17.11	0.0%	COM	87164F105
KALV	KALVISTA PHARMACEUTICALS INC	1,370,000	$11,604	1.9%	$10.36	0.0%	COM	483497103
—	UNICYCIVE THERAPEUTICS INC	10,000,000	$7,942	1.3%	$0.46	—	COM	90466Y103
—	REGULUS THERAPEUTICS INC	4,848,802	$7,661	1.3%	$1.76	—	COM	75915K309
CATX	PERSPECTIVE THERAPEUTICS INC	2,304,752	$7,352	1.2%	$12.05	-32.2%	COM NEW	46489V302
NGNE	NEUROGENE INC	303,000	$6,927	1.1%	$37.29	-0.2%	COM	64135M105
—	ALLOVIR INC	11,215,000	$4,710	0.8%	$0.42	—	COM	019818202
ATYR	ATYR PHARMA INC	900,000	$3,258	0.5%	$3.03	0.0%	COM NEW	002120202
BBOT	HELIX ACQUISITION CORP II	250,000	$2,625	0.4%	$10.35	+1.5%	CL A ORD SHS	G4444H101
CNTA	CENTESSA PHARMACEUTICALS PLC	152,000	$2,546	0.4%	$7.34	—	Put	152309100
—	MERSANA THERAPEUTICS INC	992,000	$1,419	0.2%	$4.48	—	COM	59045L106
—	NUVATION BIO INC	312,336	$831	0.1%	$2.29	—	*W EXP 02/10/202	67080N119