Paradigm Biocapital Advisors LP Quant / Systematic

CIK: 0001855655 · Show all filings

Period: Q2 2022 (← Previous) (Next →)

Filing Date: Aug 15, 2022

Total Value ($000): $501,530 (100.0% shares, 0.0% debt)

Holdings (23)

LEGN LEGEND BIOTECH CORP 10.7%

Value ($000) $53,823 Shares 978,596 Est. Cost $43.19 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 9.2%

Value ($000) $46,186 Shares 1,445,566 Est. Cost $30.85 Unrealized —

— MIRATI THERAPEUTICS INC 8.8%

Value ($000) $44,304 Shares 659,968 Est. Cost $78.99 Unrealized —

— SIERRA ONCOLOGY INC 8.8%

Value ($000) $44,064 Shares 801,314 Est. Cost $26.80 Unrealized —

INCY INCYTE CORP 8.4%

Value ($000) $42,243 Shares 556,043 Est. Cost $74.59 Unrealized +1.8%

ASND ASCENDIS PHARMA A/S 8.0%

Value ($000) $40,175 Shares 432,170 Est. Cost $119.79 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 7.7%

Value ($000) $38,425 Shares 163,066 Est. Cost $197.37 Unrealized +3.0%

ARGX ARGENX SE 6.7%

Value ($000) $33,651 Shares 88,816 Est. Cost $378.88 Unrealized —

IMCR IMMUNOCORE HLDGS PLC 5.0%

Value ($000) $24,901 Shares 667,417 Est. Cost $32.64 Unrealized —

ARVN ARVINAS INC 4.3%

Value ($000) $21,778 Shares 517,406 Est. Cost $74.11 Unrealized -32.3%

BCYC BICYCLE THERAPEUTICS PLC 3.5%

Value ($000) $17,594 Shares 1,048,516 Est. Cost $16.78 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 3.4%

Value ($000) $16,857 Shares 876,156 Est. Cost $17.65 Unrealized -5.6%

VRDN VIRIDIAN THERAPEUTICS INC 3.0%

Value ($000) $15,117 Shares 1,306,569 Est. Cost $18.45 Unrealized -27.1%

— MERUS N V 2.0%

Value ($000) $10,239 Shares 452,244 Est. Cost $24.74 Unrealized —

ESPR ESPERION THERAPEUTICS INC NE 1.8%

Value ($000) $8,955 Shares 1,408,050 Est. Cost $6.75 Unrealized -16.0%

TGTX TG THERAPEUTICS INC 1.7%

Value ($000) $8,350 Shares 1,964,709 Est. Cost $6.24 Unrealized 0.0%

— ALPINE IMMUNE SCIENCES INC 1.4%

Value ($000) $7,036 Shares 826,779 Est. Cost $8.70 Unrealized —

ENTA ENANTA PHARMACEUTICALS INC 1.4%

Value ($000) $7,006 Shares 148,216 Est. Cost $54.27 Unrealized 0.0%

— VOR BIOPHARMA INC 1.3%

Value ($000) $6,482 Shares 1,304,300 Est. Cost $8.40 Unrealized —

— OYSTER PT PHARMA INC 1.2%

Value ($000) $5,773 Shares 1,333,330 Est. Cost $11.26 Unrealized —

— GRACELL BIOTECHNOLOGIES INC 0.9%

Value ($000) $4,309 Shares 783,445 Est. Cost $4.91 Unrealized —

LQDA LIQUIDIA CORPORATION 0.7%

Value ($000) $3,710 Shares 850,961 Est. Cost $5.17 Unrealized 0.0%

CCCC C4 THERAPEUTICS INC 0.1%

Value ($000) $552 Shares 73,149 Est. Cost $32.19 Unrealized -72.7%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
LEGN	LEGEND BIOTECH CORP	978,596	$53,823	10.7%	$43.19	—	SPONSORED ADS	52490G102
—	GLOBAL BLOOD THERAPEUTICS IN	1,445,566	$46,186	9.2%	$30.85	—	COM	37890U108
—	MIRATI THERAPEUTICS INC	659,968	$44,304	8.8%	$78.99	—	COM	60468T105
—	SIERRA ONCOLOGY INC	801,314	$44,064	8.8%	$26.80	—	COM NEW	82640U404
INCY	INCYTE CORP	556,043	$42,243	8.4%	$74.59	+1.8%	COM	45337C102
ASND	ASCENDIS PHARMA A/S	432,170	$40,175	8.0%	$119.79	—	SPONSORED ADR	04351P101
UTHR	UNITED THERAPEUTICS CORP DEL	163,066	$38,425	7.7%	$197.37	+3.0%	COM	91307C102
ARGX	ARGENX SE	88,816	$33,651	6.7%	$378.88	—	SPONSORED ADR	04016X101
IMCR	IMMUNOCORE HLDGS PLC	667,417	$24,901	5.0%	$32.64	—	ADS	45258D105
ARVN	ARVINAS INC	517,406	$21,778	4.3%	$74.11	-32.3%	COM	04335A105
BCYC	BICYCLE THERAPEUTICS PLC	1,048,516	$17,594	3.5%	$16.78	—	SPONSORED ADS	088786108
SNDX	SYNDAX PHARMACEUTICALS INC	876,156	$16,857	3.4%	$17.65	-5.6%	COM	87164F105
VRDN	VIRIDIAN THERAPEUTICS INC	1,306,569	$15,117	3.0%	$18.45	-27.1%	COM	92790C104
—	MERUS N V	452,244	$10,239	2.0%	$24.74	—	COM	N5749R100
ESPR	ESPERION THERAPEUTICS INC NE	1,408,050	$8,955	1.8%	$6.75	-16.0%	COM	29664W105
TGTX	TG THERAPEUTICS INC	1,964,709	$8,350	1.7%	$6.24	0.0%	COM	88322Q108
—	ALPINE IMMUNE SCIENCES INC	826,779	$7,036	1.4%	$8.70	—	COM	02083G100
ENTA	ENANTA PHARMACEUTICALS INC	148,216	$7,006	1.4%	$54.27	0.0%	COM	29251M106
—	VOR BIOPHARMA INC	1,304,300	$6,482	1.3%	$8.40	—	COM	929033108
—	OYSTER PT PHARMA INC	1,333,330	$5,773	1.2%	$11.26	—	COM	69242L106
—	GRACELL BIOTECHNOLOGIES INC	783,445	$4,309	0.9%	$4.91	—	SPONSORED ADS	38406L103
LQDA	LIQUIDIA CORPORATION	850,961	$3,710	0.7%	$5.17	0.0%	COM NEW	53635D202
CCCC	C4 THERAPEUTICS INC	73,149	$552	0.1%	$32.19	-72.7%	COM STK	12529R107