Location: Greenwich, CT
CIK: 0001856083 · Show all filings
Period: Q4 2024 (← Previous) (Next →)
Filing Date: Feb 14, 2025
Total Value: $2.681B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | DYNAVAX TECHNOLOGIES CORP | 17,791,486 | $227M | 8.5% | $11.53 | — | COM NEW | 268158201 |
| GH | GUARDANT HEALTH INC | 6,419,566 | $196M | 7.3% | $29.38 | -4.2% | COM | 40131M109 |
| — | INTRA-CELLULAR THERAPIES INC | 2,000,000 | $167M | 6.2% | $60.26 | — | COM | 46116X101 |
| IMVT | IMMUNOVANT INC | 6,000,000 | $149M | 5.5% | $26.89 | +5.5% | COM | 45258J102 |
| APLS | APELLIS PHARMACEUTICALS INC | 4,274,921 | $136M | 5.1% | $45.92 | -34.5% | COM | 03753U106 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,460,756 | $125M | 4.7% | $29.46 | — | COM | 85205L107 |
| CYTK | CYTOKINETICS INC | 2,500,000 | $118M | 4.4% | $53.14 | -2.3% | COM NEW | 23282W605 |
| OCUL | OCULAR THERAPEUTIX INC | 12,836,282 | $110M | 4.1% | $4.09 | +138.4% | COM | 67576A100 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 4,522,741 | $86.7M | 3.2% | $18.46 | +17.8% | COM | 92790C104 |
| PLRX | PLIANT THERAPEUTICS INC | 5,972,257 | $78.65M | 2.9% | $21.52 | -36.5% | COM | 729139105 |
| GPCR | STRUCTURE THERAPEUTICS INC | 2,800,000 | $75.94M | 2.8% | $32.64 | — | SPONSORED ADS | 86366E106 |
| IONS | IONIS PHARMACEUTICALS INC | 1,933,928 | $67.61M | 2.5% | $41.01 | -8.9% | COM | 462222100 |
| NRIX | NURIX THERAPEUTICS INC | 3,000,000 | $56.52M | 2.1% | $12.26 | +86.9% | COM | 67080M103 |
| MBX | MBX BIOSCIENCES INC | 3,018,935 | $55.64M | 2.1% | $22.87 | -6.8% | COM | 55287L101 |
| — | 89BIO INC | 6,478,249 | $50.66M | 1.9% | $7.86 | — | COM | 282559103 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 1,450,000 | $49.89M | 1.9% | $34.36 | 0.0% | COM | 413197104 |
| DYN | DYNE THERAPEUTICS INC | 2,000,000 | $47.12M | 1.8% | $18.01 | +64.3% | COM | 26818M108 |
| SEPN | SEPTERNA INC | 1,912,929 | $43.81M | 1.6% | $23.65 | 0.0% | COM | 81734D104 |
| NMRA | NEUMORA THERAPEUTICS INC. | 4,000,000 | $42.4M | 1.6% | $11.94 | +0.4% | COM | 640979100 |
| GMAB | GENMAB A/S | 2,000,000 | $41.74M | 1.6% | $20.87 | — | SPONSORED ADS | 372303206 |
| — | AKERO THERAPEUTICS INC | 1,490,000 | $41.45M | 1.5% | $28.22 | — | COM | 00973Y108 |
| — | VERONA PHARMA PLC | 850,000 | $39.47M | 1.5% | $12.51 | — | SPONSORED ADS | 925050106 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1,540,132 | $38.92M | 1.5% | $27.17 | 0.0% | COM NEW | 15117B202 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1,000,000 | $38.6M | 1.4% | $43.60 | 0.0% | COM | 74366E102 |
| ANIP | ANI PHARMACEUTICALS INC | 649,042 | $35.88M | 1.3% | $53.22 | +7.9% | COM | 00182C103 |
| BCAX | BICARA THERAPEUTICS INC | 2,000,000 | $34.84M | 1.3% | $22.68 | -8.2% | COM | 055477103 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 14,218,903 | $33.41M | 1.2% | $2.90 | — | SPON ADS | 05280R100 |
| KRRO | KORRO BIO INC | 874,614 | $33.3M | 1.2% | $53.95 | -4.7% | COM | 500946108 |
| TERN | TERNS PHARMACEUTICALS INC | 5,576,558 | $30.89M | 1.2% | $7.29 | -7.1% | COM | 880881107 |
| ENGN | ENGENE HOLDINGS INC | 4,557,575 | $30.31M | 1.1% | $9.95 | -21.9% | COM | 29286M105 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 653,513 | $27.49M | 1.0% | $49.61 | 0.0% | COM | 90400D108 |
| ABVX | ABIVAX SA | 3,579,209 | $26.2M | 1.0% | $10.70 | — | SPONSORED ADS | 00370M103 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 1,350,000 | $22.61M | 0.8% | $15.99 | — | SPONSORED ADS | 152309100 |
| BBIO | BRIDGEBIO PHARMA INC | 819,162 | $22.48M | 0.8% | $25.84 | 0.0% | COM | 10806X102 |
| GLPG | GALAPAGOS NV | 780,778 | $21.47M | 0.8% | $27.50 | — | SPON ADR | 36315X101 |
| OLMA | OLEMA PHARMACEUTICALS INC | 3,442,833 | $20.07M | 0.7% | $11.20 | -10.8% | COM | 68062P106 |
| — | MIND MEDICINE MINDMED INC | 2,816,594 | $19.6M | 0.7% | $8.90 | — | COM NEW | 60255C885 |
| EWTX | EDGEWISE THERAPEUTICS INC | 710,421 | $18.97M | 0.7% | $19.48 | +63.5% | COM | 28036F105 |
| BCYC | BICYCLE THERAPEUTICS PLC | 1,276,081 | $17.87M | 0.7% | $36.40 | — | SPONSORED ADS | 088786108 |
| UPB | UPSTREAM BIO INC | 1,000,000 | $16.44M | 0.6% | $22.33 | 0.0% | COM | 91678A107 |
| NVAX | NOVAVAX INC | 2,000,000 | $16.08M | 0.6% | $9.64 | 0.0% | COM NEW | 670002401 |
| IMCR | IMMUNOCORE HLDGS PLC | 519,376 | $15.32M | 0.6% | $29.50 | — | ADS | 45258D105 |
| ORKA | ORUKA THERAPEUTICS INC | 750,000 | $14.54M | 0.5% | $34.79 | -29.9% | COM | 687604108 |
| GERN | GERON CORP | 4,011,287 | $14.2M | 0.5% | $2.57 | +55.4% | COM | 374163103 |
| HELP | CYBIN INC | 1,529,987 | $13.49M | 0.5% | $9.89 | +2.6% | COM NEW | 23256X407 |
| NMRA | NEUMORA THERAPEUTICS INC. | 1,189,800 | $12.61M | 0.5% | $11.94 | +0.4% | Call | 640979100 |
| XNCR | XENCOR INC | 500,000 | $11.49M | 0.4% | $18.77 | +22.4% | COM | 98401F105 |
| ALGS | ALIGOS THERAPEUTICS INC | 244,110 | $9.725M | 0.4% | $12.44 | +55.4% | COM NEW | 01626L204 |
| — | RAPT THERAPEUTICS INC | 6,011,380 | $9.498M | 0.4% | $1.58 | — | COM | 75382E109 |
| ZURA | ZURA BIO LTD | 3,283,783 | $8.209M | 0.3% | $7.12 | -49.9% | CLASS A ORD SHS | G9TY5A101 |
| CNTX | CONTEXT THERAPEUTICS INC | 7,419,355 | $7.79M | 0.3% | $1.72 | +0.4% | COM | 21077P108 |
| — | ALLAKOS INC | 5,704,282 | $6.902M | 0.3% | $1.90 | — | COM | 01671P100 |
| XENE | XENON PHARMACEUTICALS INC | 169,132 | $6.63M | 0.2% | $41.35 | 0.0% | COM | 98420N105 |
| AVTX | AVALO THERAPEUTICS INC | 867,000 | $6.442M | 0.2% | $10.31 | +3.7% | COM NEW | 05338F306 |
| INO | INOVIO PHARMACEUTICALS INC | 3,119,162 | $5.708M | 0.2% | $7.95 | -44.3% | COM SHS | 45773H409 |
| — | REGULUS THERAPEUTICS INC | 3,262,564 | $5.155M | 0.2% | $2.88 | — | COM | 75915K309 |
| SYRE | SPYRE THERAPEUTICS INC | 219,015 | $5.099M | 0.2% | $19.95 | +47.0% | COM NEW | 00773J202 |
| IVVD | INVIVYD INC | 10,689,603 | $4.737M | 0.2% | $4.13 | -81.2% | COM | 00534A102 |
| OKUR | ONKURE THERAPEUTICS INC | 523,989 | $4.506M | 0.2% | $15.14 | 0.0% | COM CL A | 68277Q105 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 609,900 | $3.397M | 0.1% | $21.92 | -64.2% | COM | 35104E100 |
| CLYM | CLIMB BIO INC | 1,040,115 | $1.872M | 0.1% | $6.66 | -45.6% | COM | 28658R106 |
| — | NEKTAR THERAPEUTICS | 1,975,998 | $1.838M | 0.1% | $0.59 | — | COM | 640268108 |
| SAVA | CASSAVA SCIENCES INC | 500,000 | $1.18M | 0.0% | — | — | Put | 14817C107 |