Location: Greenwich, CT
CIK: 0001856083 · Show all filings
Period: Q1 2025 (← Previous) (Next →)
Filing Date: May 15, 2025
Total Value: $3.088B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | INTRA-CELLULAR THERAPIES INC | 2,000,000 | $264M | 8.5% | $60.26 | — | COM | 46116X101 |
| GH | GUARDANT HEALTH INC | 5,443,721 | $232M | 7.5% | $29.38 | +46.9% | COM | 40131M109 |
| — | DYNAVAX TECHNOLOGIES CORP | 17,791,486 | $231M | 7.5% | $11.53 | — | COM NEW | 268158201 |
| IMVT | IMMUNOVANT INC | 9,500,000 | $162M | 5.3% | $24.69 | -15.3% | COM | 45258J102 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 3,000,000 | $145M | 4.7% | $42.47 | -1.3% | COM | 74366E102 |
| IONS | IONIS PHARMACEUTICALS INC | 4,564,207 | $138M | 4.5% | $36.25 | -9.7% | COM | 462222100 |
| — | AKERO THERAPEUTICS INC | 3,210,270 | $130M | 4.2% | $34.79 | — | COM | 00973Y108 |
| CYTK | CYTOKINETICS INC | 3,073,853 | $124M | 4.0% | $51.80 | -11.3% | COM NEW | 23282W605 |
| APLS | APELLIS PHARMACEUTICALS INC | 5,000,000 | $109M | 3.5% | $43.26 | -36.1% | COM | 03753U106 |
| OCUL | OCULAR THERAPEUTIX INC | 14,294,420 | $105M | 3.4% | $4.46 | +72.4% | COM | 67576A100 |
| BBIO | BRIDGEBIO PHARMA INC | 2,800,000 | $96.8M | 3.1% | $31.41 | +7.3% | COM | 10806X102 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,484,266 | $76.25M | 2.5% | $49.43 | 0.0% | COM | 87650L103 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 5,380,449 | $72.53M | 2.3% | $18.23 | -6.6% | COM | 92790C104 |
| GPCR | STRUCTURE THERAPEUTICS INC | 4,100,000 | $70.97M | 2.3% | $27.78 | — | SPONSORED ADS | 86366E106 |
| — | 89BIO INC | 9,316,333 | $67.73M | 2.2% | $7.68 | — | COM | 282559103 |
| NRIX | NURIX THERAPEUTICS INC | 5,500,000 | $65.34M | 2.1% | $14.29 | +17.0% | COM | 67080M103 |
| GERN | GERON CORP | 38,176,251 | $60.7M | 2.0% | $2.45 | -0.6% | COM | 374163103 |
| SRPT | SAREPTA THERAPEUTICS INC | 899,731 | $57.42M | 1.9% | $105.27 | 0.0% | COM | 803607100 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,350,000 | $48.88M | 1.6% | $45.48 | -8.5% | COM | 90400D108 |
| ANIP | ANI PHARMACEUTICALS INC | 700,000 | $46.87M | 1.5% | $53.69 | +11.2% | COM | 00182C103 |
| DNTH | DIANTHUS THERAPEUTICS INC | 2,357,702 | $42.77M | 1.4% | $22.04 | 0.0% | COM | 252828108 |
| IMCR | IMMUNOCORE HLDGS PLC | 1,411,402 | $41.88M | 1.4% | $29.61 | — | ADS | 45258D105 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 2,000,000 | $36.3M | 1.2% | $26.06 | -14.3% | COM NEW | 15117B202 |
| MAZE | MAZE THERAPEUTICS INC | 3,269,126 | $35.99M | 1.2% | $12.04 | 0.0% | COM | 578784100 |
| AMGN | AMGEN INC | 113,035 | $35.22M | 1.1% | $287.24 | 0.0% | COM | 031162100 |
| XENE | XENON PHARMACEUTICALS INC | 1,000,000 | $33.55M | 1.1% | $38.54 | -1.5% | COM | 98420N105 |
| EWTX | EDGEWISE THERAPEUTICS INC | 1,400,000 | $30.8M | 1.0% | $22.81 | +15.0% | COM | 28036F105 |
| — | METSERA INC | 1,094,408 | $29.79M | 1.0% | $27.22 | — | COM | 59267L107 |
| PCVX | VAXCYTE INC | 750,000 | $28.32M | 0.9% | $79.95 | 0.0% | COM | 92243G108 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 17,849,482 | $27.67M | 0.9% | $2.62 | — | SPON ADS | 05280R100 |
| BCAX | BICARA THERAPEUTICS INC | 2,000,000 | $26.06M | 0.8% | $22.68 | -41.4% | COM | 055477103 |
| CMPS | COMPASS PATHWAYS PLC | 8,859,648 | $25.34M | 0.8% | $2.86 | — | SPONSORED ADS | 20451W101 |
| TECX | TECTONIC THERAPEUTIC INC | 1,401,938 | $24.83M | 0.8% | $32.59 | 0.0% | COM | 878972108 |
| ABVX | ABIVAX SA | 3,579,209 | $22.37M | 0.7% | $10.70 | — | SPONSORED ADS | 00370M103 |
| MBX | MBX BIOSCIENCES INC | 3,018,935 | $22.28M | 0.7% | $22.87 | -53.8% | COM | 55287L101 |
| GHRS | GH RESEARCH PLC | 2,000,000 | $22.06M | 0.7% | $11.18 | 0.0% | ORDINARY SHARES | G3855L106 |
| DYN | DYNE THERAPEUTICS INC | 2,000,000 | $20.92M | 0.7% | $18.01 | -20.6% | COM | 26818M108 |
| ENGN | ENGENE HOLDINGS INC | 4,557,575 | $20.42M | 0.7% | $9.95 | -37.6% | COM | 29286M105 |
| INSM | INSMED INC | 254,751 | $19.43M | 0.6% | $76.49 | 0.0% | COM PAR $.01 | 457669307 |
| GLPG | GALAPAGOS NV | 741,068 | $18.62M | 0.6% | $27.50 | — | SPON ADR | 36315X101 |
| — | SAGE THERAPEUTICS INC | 2,038,845 | $16.21M | 0.5% | $7.95 | — | COM | 78667J108 |
| TERN | TERNS PHARMACEUTICALS INC | 5,576,558 | $15.39M | 0.5% | $7.29 | -43.9% | COM | 880881107 |
| KRRO | KORRO BIO INC | 874,614 | $15.23M | 0.5% | $53.95 | -45.0% | COM | 500946108 |
| ORKA | ORUKA THERAPEUTICS INC | 1,444,709 | $14.82M | 0.5% | $24.06 | -48.2% | COM | 687604108 |
| — | MIND MEDICINE MINDMED INC | 2,500,000 | $14.63M | 0.5% | $8.90 | — | COM NEW | 60255C885 |
| UPB | UPSTREAM BIO INC | 2,299,567 | $14.07M | 0.5% | $15.11 | -36.8% | COM | 91678A107 |
| OLMA | OLEMA PHARMACEUTICALS INC | 3,442,833 | $12.95M | 0.4% | $11.20 | -55.1% | COM | 68062P106 |
| SEPN | SEPTERNA INC | 1,912,929 | $11.08M | 0.4% | $23.65 | -51.7% | COM | 81734D104 |
| NVAX | NOVAVAX INC | 1,518,182 | $9.732M | 0.3% | $9.64 | -14.3% | COM NEW | 670002401 |
| HELP | CYBIN INC | 1,529,987 | $9.7M | 0.3% | $9.89 | -12.5% | COM NEW | 23256X407 |
| — | RAPT THERAPEUTICS INC | 6,011,380 | $7.334M | 0.2% | $1.58 | — | COM | 75382E109 |
| PLRX | PLIANT THERAPEUTICS INC | 5,399,681 | $7.29M | 0.2% | $21.52 | -71.8% | COM | 729139105 |
| AVTX | AVALO THERAPEUTICS INC | 859,876 | $6.888M | 0.2% | $10.31 | -26.5% | COM NEW | 05338F306 |
| BCYC | BICYCLE THERAPEUTICS PLC | 767,016 | $6.512M | 0.2% | $36.40 | — | SPONSORED ADS | 088786108 |
| BEAM | BEAM THERAPEUTICS INC | 315,765 | $6.167M | 0.2% | $26.20 | 0.0% | COM | 07373V105 |
| IVVD | INVIVYD INC | 9,722,254 | $5.885M | 0.2% | $4.13 | -78.3% | COM | 00534A102 |
| XNCR | XENCOR INC | 549,439 | $5.846M | 0.2% | $18.57 | -11.0% | COM | 98401F105 |
| — | REGULUS THERAPEUTICS INC | 3,262,564 | $5.709M | 0.2% | $2.88 | — | COM | 75915K309 |
| INO | INOVIO PHARMACEUTICALS INC | 3,119,162 | $5.084M | 0.2% | $7.95 | -74.8% | COM SHS | 45773H409 |
| RAPP | RAPPORT THERAPEUTICS INC | 457,556 | $4.589M | 0.1% | $12.98 | 0.0% | COM | 75383L102 |
| CNTX | CONTEXT THERAPEUTICS INC | 7,419,355 | $4.541M | 0.1% | $1.72 | -49.5% | COM | 21077P108 |
| ZURA | ZURA BIO LTD | 3,283,783 | $4.236M | 0.1% | $7.12 | -77.8% | CLASS A ORD SHS | G9TY5A101 |
| ALGS | ALIGOS THERAPEUTICS INC | 444,110 | $3.664M | 0.1% | $16.71 | +31.2% | COM NEW | 01626L204 |
| SYRE | SPYRE THERAPEUTICS INC | 219,015 | $3.534M | 0.1% | $19.95 | +4.3% | COM NEW | 00773J202 |
| — | IKENA ONCOLOGY INC | 2,515,513 | $3.22M | 0.1% | $1.28 | — | COM | 45175G108 |
| OKUR | ONKURE THERAPEUTICS INC | 523,989 | $2.253M | 0.1% | $15.14 | -62.9% | COM CL A | 68277Q105 |
| — | ALLAKOS INC | 7,232,701 | $1.646M | 0.1% | $1.55 | — | COM | 01671P100 |
| NGNE | NEUROGENE INC | 116,660 | $1.366M | 0.0% | $17.37 | 0.0% | COM | 64135M105 |
| CLYM | CLIMB BIO INC | 1,040,115 | $1.269M | 0.0% | $6.66 | -75.6% | COM | 28658R106 |