ARCH Venture Management, LLC Diversified Active

Location: Chicago, IL

CIK: 0001274403 · Show all filings

Period: Q1 2026 (← Previous) (Next →)

Filing Date: May 15, 2026

Total Value: $677M (100.0% shares, 0.0% debt)

Holdings (10)

New Positions (1)

GENB GENERATE BIOMEDICINES INC 3.6%

Value $24.31M Shares 1,944,426 Est. Cost $12.50 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
GENB	GENERATE BIOMEDICINES INC	1,944,426	$24.31M	3.6%	$12.50	—	COM SHS	370920100

Increased Positions (1)

LYEL LYELL IMMUNOPHARMA INC 9.6%

Value $65.14M (-23.3%) Shares 3,247,162 (+17.7%) Est. Cost $12.07 Unrealized +101.6%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
LYEL	LYELL IMMUNOPHARMA INC	3,247,162 (+17.7%)	$65.14M (-23.3%)	9.6%	$12.07	+101.6%	COM NEW	55083R203

Decreased Positions (2)

ERAS ERASCA INC 16.9%

Value $115M (+179.0%) Shares 7,091,557 (-35.9%) Est. Cost $17.12 Unrealized -41.5%

TXG 10X GENOMICS INC 0.7%

Value $4.625M (-61.6%) Shares 217,834 (-70.5%) Est. Cost $15.11 Unrealized +31.4%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ERAS	ERASCA INC	7,091,557 (-35.9%)	$115M (+179.0%)	16.9%	$17.12	-41.5%	COM	29479A108
TXG	10X GENOMICS INC	217,834 (-70.5%)	$4.625M (-61.6%)	0.7%	$15.11	+31.4%	CL A COM	88025U109

Unchanged Positions (6)

MAZE MAZE THERAPEUTICS INC 18.2%

Value $123M Shares 4,120,053 Est. Cost $12.04 Unrealized +265.8%

VIR VIR BIOTECHNOLOGY INC 17.1%

Value $116M Shares 12,916,663 Est. Cost $5.36 Unrealized +34.4%

GOSS GOSSAMER BIO INC 0.4%

Value $2.646M Shares 8,055,916 Est. Cost $1.15 Unrealized +95.8%

BEAM BEAM THERAPEUTICS INC 16.0%

Value $108M Shares 4,540,132 Est. Cost $24.56 Unrealized +18.8%

RAPP RAPPORT THERAPEUTICS INC 17.2%

Value $117M Shares 3,728,738 Est. Cost $23.15 Unrealized +20.2%

QTTB Q32 BIO INC 0.3%

Value $2.057M Shares 320,482 Est. Cost $13.78 Unrealized -71.4%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
MAZE	MAZE THERAPEUTICS INC	4,120,053	$123M	18.2%	$12.04	+265.8%	COM	578784100
VIR	VIR BIOTECHNOLOGY INC	12,916,663	$116M	17.1%	$5.36	+34.4%	COM	92764N102
GOSS	GOSSAMER BIO INC	8,055,916	$2.646M	0.4%	$1.15	+95.8%	COM	38341P102
BEAM	BEAM THERAPEUTICS INC	4,540,132	$108M	16.0%	$24.56	+18.8%	COM	07373V105
RAPP	RAPPORT THERAPEUTICS INC	3,728,738	$117M	17.2%	$23.15	+20.2%	COM	75383L102
QTTB	Q32 BIO INC	320,482	$2.057M	0.3%	$13.78	-71.4%	COM	746964105