Nextech Invest, Ltd. Long-Term Concentrated

CIK: 0001595430 · Show all filings

Period: Q4 2025 (← Previous)

Filing Date: Feb 17, 2026

Total Value ($000): $1,034,422 (100.0% shares, 0.0% debt)

Holdings (16)

New Positions (2)

ENGN ENGENE HOLDINGS INC 1.9%

Value ($000) $19,188 Shares 2,124,943 Est. Cost $8.01 Unrealized 0.0%

GLUE MONTE ROSA THERAPEUTICS INC 0.4%

Value ($000) $4,378 Shares 279,237 Est. Cost $13.48 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ENGN	ENGENE HOLDINGS INC	2,124,943	$19,188	1.9%	$8.01	0.0%	COM	29286M105
GLUE	MONTE ROSA THERAPEUTICS INC	279,237	$4,378	0.4%	$13.48	0.0%	COM	61225M102

Increased Positions (2)

RLAY RELAY THERAPEUTICS INC 3.8%

Value ($000) $39,775 (+98.1%) Shares 4,701,506 (+22.2%) Est. Cost $4.50 Unrealized +58.5%

TNGX TANGO THERAPEUTICS INC 6.2%

Value ($000) $64,377 (+38.5%) Shares 7,266,081 (+31.3%) Est. Cost $3.92 Unrealized +119.6%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RLAY	RELAY THERAPEUTICS INC	4,701,506 (+22.2%)	$39,775 (+98.1%)	3.8%	$4.50	+58.5%	COM	75943R102
TNGX	TANGO THERAPEUTICS INC	7,266,081 (+31.3%)	$64,377 (+38.5%)	6.2%	$3.92	+119.6%	COM	87583X109

Exited Positions (1)

BOLD BOUNDLESS BIO INC 0.1%

Value ($000) $1,511 Shares 1,228,069 Est. Cost $2.07 Unrealized -39.9%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
BOLD	BOUNDLESS BIO INC	1,228,069	$1,511	0.1%	$2.07	-39.9%	—	10170A100

Decreased Positions (2)

ARVN ARVINAS INC 0.6%

Value ($000) $6,397 (-46.7%) Shares 539,394 (-61.7%) Est. Cost $15.67 Unrealized -30.3%

KYMR KYMERA THERAPEUTICS INC 2.1%

Value ($000) $21,701 (+12.5%) Shares 278,896 (-18.2%) Est. Cost $34.43 Unrealized +96.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ARVN	ARVINAS INC	539,394 (-61.7%)	$6,397 (-46.7%)	0.6%	$15.67	-30.3%	COM	04335A105
KYMR	KYMERA THERAPEUTICS INC	278,896 (-18.2%)	$21,701 (+12.5%)	2.1%	$34.43	+96.1%	COM	501575104

Unchanged Positions (10)

RVMD REVOLUTION MEDICINES INC 58.5%

Value ($000) $605,427 Shares 7,601,087 Est. Cost $40.59 Unrealized +61.5%

TYRA TYRA BIOSCIENCES INC 10.3%

Value ($000) $106,629 Shares 4,055,861 Est. Cost $12.94 Unrealized +41.9%

ORIC ORIC PHARMACEUTICALS INC 5.7%

Value ($000) $58,590 Shares 7,162,637 Est. Cost $8.21 Unrealized +40.2%

ALMS ALUMIS INC 2.8%

Value ($000) $28,460 Shares 2,915,998 Est. Cost $5.28 Unrealized +32.3%

ZYME ZYMEWORKS INC 2.8%

Value ($000) $29,330 Shares 1,113,946 Est. Cost $13.64 Unrealized +59.9%

— MERSANA THERAPEUTICS INC 1.3%

Value ($000) $13,964 Shares 482,689 Est. Cost $7.76 Unrealized —

CGEM CULLINAN THERAPEUTICS INC 1.1%

Value ($000) $11,811 Shares 1,141,145 Est. Cost $9.60 Unrealized -6.0%

CNTX CONTEXT THERAPEUTICS INC 1.1%

Value ($000) $10,906 Shares 7,419,355 Est. Cost $0.87 Unrealized +34.2%

SPRY ARS PHARMACEUTICALS INC 0.7%

Value ($000) $7,697 Shares 660,703 Est. Cost $12.03 Unrealized -19.2%

SLN SILENCE THERAPEUTICS PLC 0.6%

Value ($000) $5,791 Shares 952,400 Est. Cost $2.82 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RVMD	REVOLUTION MEDICINES INC	7,601,087	$605,427	58.5%	$40.59	+61.5%	COM	76155X100
TYRA	TYRA BIOSCIENCES INC	4,055,861	$106,629	10.3%	$12.94	+41.9%	COM	90240B106
ORIC	ORIC PHARMACEUTICALS INC	7,162,637	$58,590	5.7%	$8.21	+40.2%	COM	68622P109
ALMS	ALUMIS INC	2,915,998	$28,460	2.8%	$5.28	+32.3%	COM	022307102
ZYME	ZYMEWORKS INC	1,113,946	$29,330	2.8%	$13.64	+59.9%	COM	98985Y108
—	MERSANA THERAPEUTICS INC	482,689	$13,964	1.3%	$7.76	—	COM	59045L205
CGEM	CULLINAN THERAPEUTICS INC	1,141,145	$11,811	1.1%	$9.60	-6.0%	COM	230031106
CNTX	CONTEXT THERAPEUTICS INC	7,419,355	$10,906	1.1%	$0.87	+34.2%	COM	21077P108
SPRY	ARS PHARMACEUTICALS INC	660,703	$7,697	0.7%	$12.03	-19.2%	COM	82835W108
SLN	SILENCE THERAPEUTICS PLC	952,400	$5,791	0.6%	$2.82	—	ADS	82686Q101