Rosalind Advisors, Inc. Hedge Fund

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
REPL	REPLIMUNE GROUP INC	1,410,497	$13,710	4.8%	$8.50	0.0%	COM	76029N106
AVBP	ARRIVENT BIOPHARMA INC	215,871	$4,343	1.5%	$20.82	0.0%	COM	04272N102
OKUR	ONKURE THERAPEUTICS INC	730,488	$2,118	0.7%	$2.99	0.0%	COM CL A	68277Q105
—	ANAVEX LIFE SCIENCES CORP	1,168,600	$1,881	0.7%	—	—	PUT	032797950
RGNT	REGENTIS BIOMATERIALS LTD	251,510	$1,695	0.6%	$6.86	0.0%	ORDINARY SHARES	M8211G108
NRXS	NEURAXIS INC	286,138	$1,039	0.4%	$2.99	0.0%	COM	64134X201
—	ARRIVENT BIOPHARMA INC	107,900	$540	0.2%	—	—	CALL	04272N902
—	UNIQURE NV	100,000	$95	0.0%	—	—	CALL	N90064901
—	VIKING THERAPEUTICS INC	100,000	$2	0.0%	—	—	CALL	92686J906
—	VISTAGEN THERAPEUTICS INC	493,400	$0	0.0%	—	—	CALL	92840H900
—	REPLIMUNE GROUP INC	264,700	$0	0.0%	—	—	PUT	76029N956

Increased Positions (9)

XFOR X4 PHARMACEUTICALS INC 3.7%

Value ($000) $10,424 (+97.3%) Shares 2,605,920 (+68.7%) Est. Cost $3.01 Unrealized +20.8%

PROF PROFOUND MEDICAL CORP 3.0%

Value ($000) $8,413 (+148.5%) Shares 1,068,955 (+54.4%) Est. Cost $8.06 Unrealized -20.3%

HELP CYBIN INC 4.8%

Value ($000) $13,559 (+53.5%) Shares 1,657,540 (+10.5%) Est. Cost $8.53 Unrealized -24.5%

EYPT EYEPOINT PHARMACEUTICALS INC 4.4%

Value ($000) $12,606 (+36.2%) Shares 690,000 (+6.2%) Est. Cost $11.67 Unrealized +21.5%

XERS XERIS BIOPHARMA HOLDGS INC 5.8%

Value ($000) $16,577 (+13.4%) Shares 2,111,700 (+17.6%) Est. Cost $2.76 Unrealized +185.1%

— INVESCO QQQ TR 1.1%

Value ($000) $3,029 (+94.5%) Shares 450,000 (+80.0%) Est. Cost — Unrealized —

— SPDR S&P 500 ETF TR 0.7%

Value ($000) $1,886 (+162.9%) Shares 510,000 (+70.0%) Est. Cost — Unrealized —

FENC FENNEC PHARMACEUTICALS INC 7.1%

Value ($000) $20,124 (+3.5%) Shares 2,613,508 (+25.8%) Est. Cost $6.23 Unrealized +31.7%

MYO MYOMO INC 1.2%

Value ($000) $3,494 (+3.3%) Shares 3,839,772 (+1.3%) Est. Cost $3.08 Unrealized -68.9%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
XFOR	X4 PHARMACEUTICALS INC	2,605,920 (+68.7%)	$10,424 (+97.3%)	3.7%	$3.01	+20.8%	COM NEW	98420X202
PROF	PROFOUND MEDICAL CORP	1,068,955 (+54.4%)	$8,413 (+148.5%)	3.0%	$8.06	-20.3%	COM NEW	74319B502
HELP	CYBIN INC	1,657,540 (+10.5%)	$13,559 (+53.5%)	4.8%	$8.53	-24.5%	COM NEW	23256X407
EYPT	EYEPOINT PHARMACEUTICALS INC	690,000 (+6.2%)	$12,606 (+36.2%)	4.4%	$11.67	+21.5%	COM NEW	30233G209
XERS	XERIS BIOPHARMA HOLDGS INC	2,111,700 (+17.6%)	$16,577 (+13.4%)	5.8%	$2.76	+185.1%	COM	98422E103
—	INVESCO QQQ TR	450,000 (+80.0%)	$3,029 (+94.5%)	1.1%	—	—	PUT	46090E953
—	SPDR S&P 500 ETF TR	510,000 (+70.0%)	$1,886 (+162.9%)	0.7%	—	—	PUT	78462F953
FENC	FENNEC PHARMACEUTICALS INC	2,613,508 (+25.8%)	$20,124 (+3.5%)	7.1%	$6.23	+31.7%	COM	31447P100
MYO	MYOMO INC	3,839,772 (+1.3%)	$3,494 (+3.3%)	1.2%	$3.08	-68.9%	COM NEW	62857J201

Exited Positions (8)

RZLT REZOLUTE INC 6.0%

Value ($000) $16,988 Shares 1,807,202 Est. Cost $3.82 Unrealized +105.2%

— VERONA PHARMA PLC 3.8%

Value ($000) $10,671 Shares 100,000 Est. Cost $20.69 Unrealized —

IDYA IDEAYA BIOSCIENCES INC 3.3%

Value ($000) $9,524 Shares 350,000 Est. Cost $21.31 Unrealized +49.6%

QURE UNIQURE NV 2.6%

Value ($000) $7,296 Shares 125,000 Est. Cost $18.16 Unrealized +112.5%

— ATYR PHARMA INC 1.6%

Value ($000) $4,470 Shares 1,570,200 Est. Cost — Unrealized —

— ASTRIA THERAPEUTICS INC 0.4%

Value ($000) $1,113 Shares 1,542,520 Est. Cost $0.72 Unrealized —

— IDEAYA BIOSCIENCES INC 0.1%

Value ($000) $237 Shares 35,900 Est. Cost — Unrealized —

— SCHOLAR ROCK HLDG CORP 0.0%

Value ($000) $10 Shares 100,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RZLT	REZOLUTE INC	1,807,202	$16,988	6.0%	$3.82	+105.2%	—	76200L309
—	VERONA PHARMA PLC	100,000	$10,671	3.8%	$20.69	—	—	925050106
IDYA	IDEAYA BIOSCIENCES INC	350,000	$9,524	3.3%	$21.31	+49.6%	—	45166A102
QURE	UNIQURE NV	125,000	$7,296	2.6%	$18.16	+112.5%	—	N90064101
—	ATYR PHARMA INC	1,570,200	$4,470	1.6%	—	—	PUT	002120952
—	ASTRIA THERAPEUTICS INC	1,542,520	$1,113	0.4%	$0.72	—	—	04635X102
—	IDEAYA BIOSCIENCES INC	35,900	$237	0.1%	—	—	CALL	45166A902
—	SCHOLAR ROCK HLDG CORP	100,000	$10	0.0%	—	—	PUT	80706P953

Decreased Positions (10)

CYTK CYTOKINETICS INC 4.4%

Value ($000) $12,393 (-43.6%) Shares 195,045 (-51.2%) Est. Cost $34.78 Unrealized +78.8%

GUTS FRACTYL HEALTH INC 0.3%

Value ($000) $849 (-89.3%) Shares 385,731 (-92.3%) Est. Cost $1.30 Unrealized +24.1%

SVRA SAVARA INC 7.2%

Value ($000) $20,524 (+43.7%) Shares 3,403,721 (-14.9%) Est. Cost $3.31 Unrealized +48.0%

VSTM VERASTEM INC 4.9%

Value ($000) $13,807 (-19.0%) Shares 1,788,475 (-7.3%) Est. Cost $5.37 Unrealized +65.9%

VRDN VIRIDIAN THERAPEUTICS INC 4.9%

Value ($000) $14,004 (+8.2%) Shares 450,000 (-25.0%) Est. Cost $16.51 Unrealized +66.1%

— VERASTEM INC 0.1%

Value ($000) $160 (-82.2%) Shares 268,600 (-58.5%) Est. Cost — Unrealized —

— SPDR SERIES TRUST 0.5%

Value ($000) $1,348 (+41.8%) Shares 1,937,600 (-9.0%) Est. Cost — Unrealized —

— REPLIMUNE GROUP INC 0.0%

Value ($000) $12 (-93.7%) Shares 230,900 (-54.8%) Est. Cost — Unrealized —

TLPH TALPHERA INC 1.4%

Value ($000) $4,080 (+4.2%) Shares 3,579,273 (-18.4%) Est. Cost $0.60 Unrealized +101.8%

PYPD POLYPID LTD 1.1%

Value ($000) $3,023 (-1.3%) Shares 696,556 (-24.2%) Est. Cost $4.49 Unrealized -17.2%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
CYTK	CYTOKINETICS INC	195,045 (-51.2%)	$12,393 (-43.6%)	4.4%	$34.78	+78.8%	COM NEW	23282W605
GUTS	FRACTYL HEALTH INC	385,731 (-92.3%)	$849 (-89.3%)	0.3%	$1.30	+24.1%	COM	35168W103
SVRA	SAVARA INC	3,403,721 (-14.9%)	$20,524 (+43.7%)	7.2%	$3.31	+48.0%	COM	805111101
VSTM	VERASTEM INC	1,788,475 (-7.3%)	$13,807 (-19.0%)	4.9%	$5.37	+65.9%	COM NEW	92337C203
VRDN	VIRIDIAN THERAPEUTICS INC	450,000 (-25.0%)	$14,004 (+8.2%)	4.9%	$16.51	+66.1%	COM	92790C104
—	VERASTEM INC	268,600 (-58.5%)	$160 (-82.2%)	0.1%	—	—	CALL	92337C903
—	SPDR SERIES TRUST	1,937,600 (-9.0%)	$1,348 (+41.8%)	0.5%	—	—	PUT	78464A950
—	REPLIMUNE GROUP INC	230,900 (-54.8%)	$12 (-93.7%)	0.0%	—	—	CALL	76029N906
TLPH	TALPHERA INC	3,579,273 (-18.4%)	$4,080 (+4.2%)	1.4%	$0.60	+101.8%	COM NEW	00444T209
PYPD	POLYPID LTD	696,556 (-24.2%)	$3,023 (-1.3%)	1.1%	$4.49	-17.2%	COM	M8001Q126

Unchanged Positions (12)

ATYR ASTRIA THERAPEUTICS INC 4.8%

Value ($000) $13,602 Shares 1,039,080 Est. Cost $4.53 Unrealized -81.9%

NSPR INSPIREMD INC 2.4%

Value ($000) $6,952 Shares 3,905,743 Est. Cost $2.46 Unrealized -15.4%

— MIND MEDICINE MINDMED INC 3.5%

Value ($000) $10,043 Shares 750,000 Est. Cost $8.46 Unrealized —

— ISHARES TR 0.4%

Value ($000) $1,112 Shares 200,000 Est. Cost — Unrealized —

— REZOLUTE INC 0.0%

Value ($000) $0 Shares 263,100 Est. Cost — Unrealized —

BFRI BIOFRONTERA INC 0.2%

Value ($000) $650 Shares 1,140,764 Est. Cost $1.02 Unrealized -11.4%

CGON CG ONCOLOGY INC 4.4%

Value ($000) $12,456 Shares 300,000 Est. Cost $25.87 Unrealized +59.9%

TRVI TREVI THERAPEUTICS INC 0.4%

Value ($000) $1,252 Shares 100,000 Est. Cost $2.31 Unrealized +400.6%

MDWD MEDIWOUND LTD 4.9%

Value ($000) $13,828 Shares 749,054 Est. Cost $14.40 Unrealized +26.9%

OCUL Ocular Therapeutix, Inc 1.7%

Value ($000) $4,856 Shares 400,000 Est. Cost $7.23 Unrealized +68.0%

KURA KURA ONCOLOGY INC 0.4%

Value ($000) $1,039 Shares 100,000 Est. Cost $7.79 Unrealized +34.6%

DCTH DELCATH SYSTEMS, INC. 11.6%

Value ($000) $33,004 Shares 3,300,389 Est. Cost $6.89 Unrealized +44.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ATYR	ASTRIA THERAPEUTICS INC	1,039,080	$13,602	4.8%	$4.53	-81.9%	COM	002120202
NSPR	INSPIREMD INC	3,905,743	$6,952	2.4%	$2.46	-15.4%	COM	45779A846
—	MIND MEDICINE MINDMED INC	750,000	$10,043	3.5%	$8.46	—	COM NEW	60255C885
—	ISHARES TR	200,000	$1,112	0.4%	—	—	PUT	464287955
—	REZOLUTE INC	263,100	$0	0.0%	—	—	CALL	76200L909
BFRI	BIOFRONTERA INC	1,140,764	$650	0.2%	$1.02	-11.4%	COM NEW	09077D209
CGON	CG ONCOLOGY INC	300,000	$12,456	4.4%	$25.87	+59.9%	COM	156944100
TRVI	TREVI THERAPEUTICS INC	100,000	$1,252	0.4%	$2.31	+400.6%	COM	89532M101
MDWD	MEDIWOUND LTD	749,054	$13,828	4.9%	$14.40	+26.9%	SHS NEW	M68830112
OCUL	Ocular Therapeutix, Inc	400,000	$4,856	1.7%	$7.23	+68.0%	COM	67576A100
KURA	KURA ONCOLOGY INC	100,000	$1,039	0.4%	$7.79	+34.6%	COM	50127T109
DCTH	DELCATH SYSTEMS, INC.	3,300,389	$33,004	11.6%	$6.89	+44.3%	COM NEW	24661P807