Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
CLST	Catalyst Pharmaceuticals, Inc.	114,000	$3.583M	1.9%	$31.43	—	Common	14888L101
SPRB	Spruce Biosciences, Inc.	20,000	$1.08M	0.6%	$54.00	—	Common	85209E208
—	DuPont de Nemours, Inc.	3,767	$511K	0.3%	$135.64	—	Common	36614N201
INSM	Insmed Incorporated	4,253	$453K	0.2%	$106.62	—	Common	457669307
LBRX	LB Pharmaceuticals, Inc.	12,965	$421K	0.2%	$32.45	—	Common	50180M108
CDNA	CareDx, Inc.	13,630	$388K	0.2%	$28.50	—	Common	14167L103
QTTB	Q32 Bio Inc	30,412	$387K	0.2%	$12.74	—	Common	746964105
ELVN	Enliven Therapeutics, Inc.	6,183	$314K	0.2%	$50.75	—	Common	29337E102
BSX	Boston Scientific Corporation	6,000	$256K	0.1%	$42.68	—	Common	101137107
FSK	FS KKR Capital Corp.	2,875	$30,187	0.0%	$10.50	—	Common	302635206
OXY/WS	Occidential Pertro Wts exp. 8/3/27	194	$4,268	0.0%	$22.00	—	Common	674599162

Increased Positions (16)

TVTX Travere Therapeutics, Inc. 4.4%

Value $8.367M (+100.3%) Shares 147,282 (+4.7%) Est. Cost $12.74 Unrealized —

ALKS Alkermes PLC 3.4%

Value $6.38M (+50.3%) Shares 121,759 (+1.5%) Est. Cost $30.74 Unrealized —

CGEM Cullinan Therapeutics, Inc. 0.7%

Value $1.26M (+266.3%) Shares 69,182 (+185.9%) Est. Cost $16.03 Unrealized —

HELP Cybin Inc 1.3%

Value $2.446M (+45.6%) Shares 370,000 (+5.7%) Est. Cost $7.34 Unrealized —

RARE Ultragenyx Pharmaceutical Inc. 0.7%

Value $1.271M (+83.5%) Shares 38,069 (+15.1%) Est. Cost $34.04 Unrealized —

MDGL Madrigal Pharmaaceuticals, Inc. 0.9%

Value $1.611M (+53.9%) Shares 3,000 (+50.0%) Est. Cost $377.61 Unrealized —

AGIO Agios Pharmaceutical, Inc. 1.9%

Value $3.528M (+12.1%) Shares 95,058 (+2.1%) Est. Cost $29.56 Unrealized —

SNDX Syndax Pharmaceutical, Inc. 5.1%

Value $9.558M (-3.0%) Shares 437,245 (+3.6%) Est. Cost $14.84 Unrealized —

COGT Cogent Biosciences Inc. 2.3%

Value $4.299M (+7.4%) Shares 111,081 (+6.8%) Est. Cost $28.95 Unrealized —

BBIO Bridgebio Pharma, Inc. 3.7%

Value $6.915M (+3.5%) Shares 92,850 (+3.2%) Est. Cost $40.26 Unrealized —

SLDB Solid Bioscience Inc. 0.3%

Value $562K (+65.4%) Shares 56,208 (+19.2%) Est. Cost $5.08 Unrealized —

PTHS Pelthos Therapeutics, Inc. 0.3%

Value $624K (+40.9%) Shares 22,073 (+4.7%) Est. Cost $27.17 Unrealized —

ARDX Ardelyx, Inc. 0.7%

Value $1.342M (+8.2%) Shares 263,168 (+27.1%) Est. Cost $6.65 Unrealized —

RLMD Relmada Therapeutics, Inc. 1.6%

Value $3.121M (+2.1%) Shares 451,000 (+2.7%) Est. Cost $4.09 Unrealized —

CNTB Connect Biopharma Holdings Limited 0.6%

Value $1.059M (+4.2%) Shares 444,862 (+14.7%) Est. Cost $2.31 Unrealized —

VSTM Verastem Inc. 0.3%

Value $592K (+7.4%) Shares 155,000 (+49.0%) Est. Cost $5.60 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
TVTX	Travere Therapeutics, Inc.	147,282 (+4.7%)	$8.367M (+100.3%)	4.4%	$12.74	—	Common	89422G107
ALKS	Alkermes PLC	121,759 (+1.5%)	$6.38M (+50.3%)	3.4%	$30.74	—	Common	G01767105
CGEM	Cullinan Therapeutics, Inc.	69,182 (+185.9%)	$1.26M (+266.3%)	0.7%	$16.03	—	Common	230031106
HELP	Cybin Inc	370,000 (+5.7%)	$2.446M (+45.6%)	1.3%	$7.34	—	Common	23256X407
RARE	Ultragenyx Pharmaceutical Inc.	38,069 (+15.1%)	$1.271M (+83.5%)	0.7%	$34.04	—	Common	90400D108
MDGL	Madrigal Pharmaaceuticals, Inc.	3,000 (+50.0%)	$1.611M (+53.9%)	0.9%	$377.61	—	Common	558868105
AGIO	Agios Pharmaceutical, Inc.	95,058 (+2.1%)	$3.528M (+12.1%)	1.9%	$29.56	—	Common	00847X104
SNDX	Syndax Pharmaceutical, Inc.	437,245 (+3.6%)	$9.558M (-3.0%)	5.1%	$14.84	—	Common	87164F105
COGT	Cogent Biosciences Inc.	111,081 (+6.8%)	$4.299M (+7.4%)	2.3%	$28.95	—	Common	19240Q201
BBIO	Bridgebio Pharma, Inc.	92,850 (+3.2%)	$6.915M (+3.5%)	3.7%	$40.26	—	Common	10806X102
SLDB	Solid Bioscience Inc.	56,208 (+19.2%)	$562K (+65.4%)	0.3%	$5.08	—	Common	83422E204
PTHS	Pelthos Therapeutics, Inc.	22,073 (+4.7%)	$624K (+40.9%)	0.3%	$27.17	—	Common	171126204
ARDX	Ardelyx, Inc.	263,168 (+27.1%)	$1.342M (+8.2%)	0.7%	$6.65	—	Common	039697107
RLMD	Relmada Therapeutics, Inc.	451,000 (+2.7%)	$3.121M (+2.1%)	1.6%	$4.09	—	Common	75955J402
CNTB	Connect Biopharma Holdings Limited	444,862 (+14.7%)	$1.059M (+4.2%)	0.6%	$2.31	—	Common	G23549101
VSTM	Verastem Inc.	155,000 (+49.0%)	$592K (+7.4%)	0.3%	$5.60	—	Common	92337C203

Exited Positions (12)

CPRX Catalyst Pharmaceuticals, Inc. 1.6%

Value $2.971M Shares 120,000 Est. Cost $14.73 Unrealized —

— Arcellx Inc 1.2%

Value $2.231M Shares 19,433 Est. Cost $82.10 Unrealized —

CYTK Cytokinetics, Incorporated 0.8%

Value $1.558M Shares 23,644 Est. Cost $43.67 Unrealized —

CNTA Centessa Pharmaceuticals PLC 0.8%

Value $1.549M Shares 39,000 Est. Cost $38.21 Unrealized —

ADMA ADMA Biologics, Inc. 0.3%

Value $542K Shares 60,200 Est. Cost $16.85 Unrealized —

— Biohaven Pharmaceutical Holding Co. Ltd 0.3%

Value $514K Shares 60,720 Est. Cost $8.46 Unrealized —

— Evolus, Inc. 0.2%

Value $408K Shares 99,338 Est. Cost $6.65 Unrealized —

LENZ LENZ Therapeutics, Inc. 0.2%

Value $309K Shares 33,732 Est. Cost $27.20 Unrealized —

DD DuPont de Nemours, Inc. 0.1%

Value $173K Shares 3,767 Est. Cost $29.21 Unrealized —

JSPR Jasper Therapeutics, Inc. 0.1%

Value $141K Shares 160,789 Est. Cost $2.98 Unrealized —

MREO Mereo BioPharm Group PLC 0.1%

Value $99,111 Shares 300,337 Est. Cost $3.72 Unrealized —

— FS KKR Capital Corp. 0.0%

Value $29,267 Shares 2,875 Est. Cost $10.18 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
CPRX	Catalyst Pharmaceuticals, Inc.	120,000	$2.971M	1.6%	$14.73	—	—	14888U101
—	Arcellx Inc	19,433	$2.231M	1.2%	$82.10	—	—	03940c100
CYTK	Cytokinetics, Incorporated	23,644	$1.558M	0.8%	$43.67	—	—	23282W605
CNTA	Centessa Pharmaceuticals PLC	39,000	$1.549M	0.8%	$38.21	—	—	152309100
ADMA	ADMA Biologics, Inc.	60,200	$542K	0.3%	$16.85	—	—	000899104
—	Biohaven Pharmaceutical Holding Co. Ltd	60,720	$514K	0.3%	$8.46	—	—	G111OE107
—	Evolus, Inc.	99,338	$408K	0.2%	$6.65	—	—	30052c107
LENZ	LENZ Therapeutics, Inc.	33,732	$309K	0.2%	$27.20	—	—	52635N103
DD	DuPont de Nemours, Inc.	3,767	$173K	0.1%	$29.21	—	—	26614N102
JSPR	Jasper Therapeutics, Inc.	160,789	$141K	0.1%	$2.98	—	—	471871202
MREO	Mereo BioPharm Group PLC	300,337	$99,111	0.1%	$3.72	—	—	589492107
—	FS KKR Capital Corp.	2,875	$29,267	0.0%	$10.18	—	—	302635107

Decreased Positions (4)

BMY Bristol-Myers Squibb Company 0.1%

Value $115K (-86.1%) Shares 2,000 (-85.3%) Est. Cost $53.03 Unrealized —

TGTX TG Therapeutics, Inc. 1.9%

Value $3.672M (+22.8%) Shares 66,839 (-25.7%) Est. Cost $31.16 Unrealized —

JPM JPMorgan Chase & Co. 3.1%

Value $5.924M (+3.4%) Shares 18,098 (-7.1%) Est. Cost $142.30 Unrealized —

OXY Occidental Petroleum Corporation 0.0%

Value $22,779 (-34.4%) Shares 469 (-29.3%) Est. Cost $36.77 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
BMY	Bristol-Myers Squibb Company	2,000 (-85.3%)	$115K (-86.1%)	0.1%	$53.03	—	Common	110122108
TGTX	TG Therapeutics, Inc.	66,839 (-25.7%)	$3.672M (+22.8%)	1.9%	$31.16	—	Common	88322Q108
JPM	JPMorgan Chase & Co.	18,098 (-7.1%)	$5.924M (+3.4%)	3.1%	$142.30	—	Common	46625H100
OXY	Occidental Petroleum Corporation	469 (-29.3%)	$22,779 (-34.4%)	0.0%	$36.77	—	Common	674599105

Unchanged Positions (53)

GOOG Alphabet Inc-Cl C 17.1%

Value $32.3M Shares 91,420 Est. Cost $112.46 Unrealized —

XERS Xeris Biopharma Holdings, Inc. 4.4%

Value $8.395M Shares 1,060,000 Est. Cost $2.77 Unrealized —

APO Apollo Global Management, Inc. 14.1%

Value $26.62M Shares 225,000 Est. Cost $64.08 Unrealized —

PTGX Protagonist Therapeutics, Inc 4.1%

Value $7.723M Shares 63,000 Est. Cost $28.54 Unrealized —

IOVA Iovance Biotherapeutics, Inc. 3.5%

Value $6.656M Shares 1,600,000 Est. Cost $2.68 Unrealized —

RZLT Rezolute, Inc. 1.0%

Value $1.924M Shares 370,000 Est. Cost $6.57 Unrealized —

RCUS Arcus Biosciences, Inc. 1.3%

Value $2.505M Shares 81,241 Est. Cost $11.78 Unrealized —

XBI SPDR S&P Biotech ETF 1.3%

Value $2.374M Shares 15,000 Est. Cost $113.51 Unrealized —

— LPL Financial Holdings Inc. 2.5%

Value $4.648M Shares 16,500 Est. Cost $300.83 Unrealized —

DCGO DocGo, Inc. 0.7%

Value $1.378M Shares 2,670,850 Est. Cost $6.66 Unrealized —

VRDN Viridian Therapeutics, Inc. 1.8%

Value $3.325M Shares 181,000 Est. Cost $21.03 Unrealized —

CNQ Canadian Natural Resources Limited 0.4%

Value $664K Shares 16,800 Est. Cost $27.07 Unrealized —

KURA Kura Oncology, Inc. 0.3%

Value $579K Shares 52,767 Est. Cost $7.51 Unrealized —

BIIB Biogen Inc. 0.5%

Value $864K Shares 4,000 Est. Cost $153.97 Unrealized —

PFE Pfizer Inc. 0.4%

Value $779K Shares 32,337 Est. Cost $30.29 Unrealized —

IBB iShares Biotechnology ETF 0.6%

Value $1.046M Shares 5,500 Est. Cost $142.31 Unrealized —

AB AllianceBernstein Holding L.P. 0.9%

Value $1.691M Shares 48,000 Est. Cost $48.83 Unrealized —

AAPL Apple Inc. 0.4%

Value $722K Shares 2,494 Est. Cost $153.75 Unrealized —

RHP Ryman Hospitality Properties, Inc. 0.2%

Value $309K Shares 2,400 Est. Cost $92.38 Unrealized —

IBM International Business Machines 0.3%

Value $602K Shares 2,142 Est. Cost $120.73 Unrealized —

VERA Vera Therapeutics, Inc. 0.6%

Value $1.116M Shares 26,000 Est. Cost $26.34 Unrealized —

WVE Wave Life Science Ltd. 0.1%

Value $232K Shares 40,000 Est. Cost $7.91 Unrealized —

AVGO Broadcom, Inc. 0.1%

Value $268K Shares 710 Est. Cost $147.45 Unrealized —

RAIN Rain Enhancement Technologies Holdco Inc 0.1%

Value $210K Shares 101,686 Est. Cost $2.94 Unrealized —

JNJ Johnson & Johnson 0.7%

Value $1.25M Shares 4,922 Est. Cost $150.82 Unrealized —

IVVD Invivyd, Inc. 0.0%

Value $87,240 Shares 100,000 Est. Cost $0.89 Unrealized —

CLOZ The Panagram BBB-B CLO ETF 0.7%

Value $1.263M Shares 47,807 Est. Cost $26.36 Unrealized —

NVDA Nvidia Corp 0.1%

Value $256K Shares 1,280 Est. Cost $92.83 Unrealized —

KMB Kimberly-Clark Corporation 0.1%

Value $263K Shares 2,400 Est. Cost $115.26 Unrealized —

URI United Rental, Inc. 0.0%

Value $88,365 Shares 78 Est. Cost $284.96 Unrealized —

PWR Quanta Services, Inc. 0.1%

Value $127K Shares 176 Est. Cost $220.68 Unrealized —

ATRC AtriCure, Inc. 0.8%

Value $1.438M Shares 51,400 Est. Cost $35.05 Unrealized —

LEGH Legacy Housing Corporation 0.1%

Value $105K Shares 4,000 Est. Cost $22.33 Unrealized —

— Alphabet Inc CL A 0.1%

Value $107K Shares 300 Est. Cost $1656.67 Unrealized —

DOW Dow Inc. 0.0%

Value $32,996 Shares 1,206 Est. Cost $45.04 Unrealized —

OBIO Orchestra Biomed Holdings, Inc. 0.6%

Value $1.095M Shares 253,651 Est. Cost $3.12 Unrealized —

EBC Eastern Bankshares Inc 0.1%

Value $111K Shares 5,000 Est. Cost $14.08 Unrealized —

IWP iShares Russell Mid-Cap Growth 0.1%

Value $102K Shares 695 Est. Cost $136.94 Unrealized —

JAAA Janus Henderson AAA CLO ETF 2.5%

Value $4.722M Shares 93,528 Est. Cost $50.69 Unrealized —

AMZN Amazon.com Inc. 0.0%

Value $71,502 Shares 300 Est. Cost $125.13 Unrealized —

— United Healthcare Corp. 0.0%

Value $23,691 Shares 57 Est. Cost $508.77 Unrealized —

BRSL International Game Technology PLC 0.0%

Value $26,800 Shares 2,500 Est. Cost $14.25 Unrealized —

MSFT Microsoft Corporation 0.3%

Value $597K Shares 1,600 Est. Cost $307.17 Unrealized —

CRM Salesforce, Inc. 0.0%

Value $12,063 Shares 77 Est. Cost $174.57 Unrealized —

CTVA Corteva, Inc. 0.1%

Value $102K Shares 1,206 Est. Cost $43.54 Unrealized —

KD Kyndryl Holdings Inc. 0.0%

Value $4,841 Shares 428 Est. Cost $14.19 Unrealized —

MDLZ Mondelez International, Inc. 0.1%

Value $174K Shares 3,000 Est. Cost $63.41 Unrealized —

— Blackstone Group LP 0.0%

Value $24,711 Shares 210 Est. Cost $95.24 Unrealized —

TMO Thermo Fisher Scientific, Inc. 0.0%

Value $22,561 Shares 45 Est. Cost $544.70 Unrealized —

GEHC GE HealthCare Technologies Inc 0.0%

Value $3,200 Shares 50 Est. Cost $69.79 Unrealized —

STWD Starwood Property Trust, Inc. 0.0%

Value $6,552 Shares 400 Est. Cost $25.00 Unrealized —

DHR Danaher Corporation 0.0%

Value $34,286 Shares 180 Est. Cost $226.23 Unrealized —

WAB Wabtec Corporation 0.0%

Value $1,618 Shares 6 Est. Cost $89.57 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
GOOG	Alphabet Inc-Cl C	91,420	$32.3M	17.1%	$112.46	—	Common	02079K107
XERS	Xeris Biopharma Holdings, Inc.	1,060,000	$8.395M	4.4%	$2.77	—	Common	98422E103
APO	Apollo Global Management, Inc.	225,000	$26.62M	14.1%	$64.08	—	Common	03769M106
PTGX	Protagonist Therapeutics, Inc	63,000	$7.723M	4.1%	$28.54	—	Common	74366E102
IOVA	Iovance Biotherapeutics, Inc.	1,600,000	$6.656M	3.5%	$2.68	—	Common	462260100
RZLT	Rezolute, Inc.	370,000	$1.924M	1.0%	$6.57	—	Common	76200L309
RCUS	Arcus Biosciences, Inc.	81,241	$2.505M	1.3%	$11.78	—	Common	03969F109
XBI	SPDR S&P Biotech ETF	15,000	$2.374M	1.3%	$113.51	—	Common	78464A870
—	LPL Financial Holdings Inc.	16,500	$4.648M	2.5%	$300.83	—	Common	52012V100
DCGO	DocGo, Inc.	2,670,850	$1.378M	0.7%	$6.66	—	Common	256086109
VRDN	Viridian Therapeutics, Inc.	181,000	$3.325M	1.8%	$21.03	—	Common	92790C104
CNQ	Canadian Natural Resources Limited	16,800	$664K	0.4%	$27.07	—	Common	136385101
KURA	Kura Oncology, Inc.	52,767	$579K	0.3%	$7.51	—	Common	50127T109
BIIB	Biogen Inc.	4,000	$864K	0.5%	$153.97	—	Common	09062X103
PFE	Pfizer Inc.	32,337	$779K	0.4%	$30.29	—	Common	717081103
IBB	iShares Biotechnology ETF	5,500	$1.046M	0.6%	$142.31	—	Common	464287556
AB	AllianceBernstein Holding L.P.	48,000	$1.691M	0.9%	$48.83	—	Common	01881G106
AAPL	Apple Inc.	2,494	$722K	0.4%	$153.75	—	Common	037833100
RHP	Ryman Hospitality Properties, Inc.	2,400	$309K	0.2%	$92.38	—	Common	78377T107
IBM	International Business Machines	2,142	$602K	0.3%	$120.73	—	Common	459200101
VERA	Vera Therapeutics, Inc.	26,000	$1.116M	0.6%	$26.34	—	Common	92337R101
WVE	Wave Life Science Ltd.	40,000	$232K	0.1%	$7.91	—	Common	Y95308105
AVGO	Broadcom, Inc.	710	$268K	0.1%	$147.45	—	Common	11135F101
RAIN	Rain Enhancement Technologies Holdco Inc	101,686	$210K	0.1%	$2.94	—	Common	75080J103
JNJ	Johnson & Johnson	4,922	$1.25M	0.7%	$150.82	—	Common	478160104
IVVD	Invivyd, Inc.	100,000	$87,240	0.0%	$0.89	—	Common	00534A102
CLOZ	The Panagram BBB-B CLO ETF	47,807	$1.263M	0.7%	$26.36	—	Common	81752T528
NVDA	Nvidia Corp	1,280	$256K	0.1%	$92.83	—	Common	67066G104
KMB	Kimberly-Clark Corporation	2,400	$263K	0.1%	$115.26	—	Common	494368103
URI	United Rental, Inc.	78	$88,365	0.0%	$284.96	—	Common	911363109
PWR	Quanta Services, Inc.	176	$127K	0.1%	$220.68	—	Common	74762E102
ATRC	AtriCure, Inc.	51,400	$1.438M	0.8%	$35.05	—	Common	04963C209
LEGH	Legacy Housing Corporation	4,000	$105K	0.1%	$22.33	—	Common	52472M101
—	Alphabet Inc CL A	300	$107K	0.1%	$1656.67	—	Common	02079k305
DOW	Dow Inc.	1,206	$32,996	0.0%	$45.04	—	Common	260557103
OBIO	Orchestra Biomed Holdings, Inc.	253,651	$1.095M	0.6%	$3.12	—	Common	68572M106
EBC	Eastern Bankshares Inc	5,000	$111K	0.1%	$14.08	—	Common	27627N105
IWP	iShares Russell Mid-Cap Growth	695	$102K	0.1%	$136.94	—	Common	464287481
JAAA	Janus Henderson AAA CLO ETF	93,528	$4.722M	2.5%	$50.69	—	Common	47103U845
AMZN	Amazon.com Inc.	300	$71,502	0.0%	$125.13	—	Common	023135106
—	United Healthcare Corp.	57	$23,691	0.0%	$508.77	—	Common	91324p102
BRSL	International Game Technology PLC	2,500	$26,800	0.0%	$14.25	—	Common	G4863A108
MSFT	Microsoft Corporation	1,600	$597K	0.3%	$307.17	—	Common	594918104
CRM	Salesforce, Inc.	77	$12,063	0.0%	$174.57	—	Common	79466L302
CTVA	Corteva, Inc.	1,206	$102K	0.1%	$43.54	—	Common	22052L104
KD	Kyndryl Holdings Inc.	428	$4,841	0.0%	$14.19	—	Common	50155Q100
MDLZ	Mondelez International, Inc.	3,000	$174K	0.1%	$63.41	—	Common	609207105
—	Blackstone Group LP	210	$24,711	0.0%	$95.24	—	Common	09260d107
TMO	Thermo Fisher Scientific, Inc.	45	$22,561	0.0%	$544.70	—	Common	883556102
GEHC	GE HealthCare Technologies Inc	50	$3,200	0.0%	$69.79	—	Common	36266G107
STWD	Starwood Property Trust, Inc.	400	$6,552	0.0%	$25.00	—	Common	85571B105
DHR	Danaher Corporation	180	$34,286	0.0%	$226.23	—	Common	235851102
WAB	Wabtec Corporation	6	$1,618	0.0%	$89.57	—	Common	929740108