SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

AQR CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001167557)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 17,820 Value ($000) $584 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 17,047 Value ($000) $286 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 17,973 Value ($000) $269 Avg Close $14.80 Range $10.91 - $19.20

Q3 2024

Shares 35,003 Value ($000) $1,029 Avg Close $27.85 Range $23.00 - $32.41

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	17,820	$584	$26.13	$15.86 - $35.31
Q3 2025	17,047	$286	$16.31	$14.00 - $18.30
Q2 2025	17,973	$269	$14.80	$10.91 - $19.20
Q3 2024	35,003	$1,029	$27.85	$23.00 - $32.41