SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

GREAT POINT PARTNERS LLC's Holding History (CIK: 0001281446)

Note: Option positions (PUT/CALL) are excluded.

Q2 2024

Shares 134,612 Value ($000) $3,165 Avg Close $33.73 Range $22.19 - $40.84

Q1 2024

Shares 125,000 Value ($000) $4,741 Avg Close $28.97 Range $18.54 - $47.97

Q4 2023

Shares 125,000 Value ($000) $2,690 Avg Close $13.78 Range $8.43 - $22.66

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2024	134,612	$3,165	$33.73	$22.19 - $40.84
Q1 2024	125,000	$4,741	$28.97	$18.54 - $47.97
Q4 2023	125,000	$2,690	$13.78	$8.43 - $22.66