SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

Prosight Management, LP's Holding History (CIK: 0001617201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 74,921 Value ($000) $1,209 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 80,000 Value ($000) $1,862 Avg Close $29.32 Range $22.37 - $40.26

Q4 2023

Shares 55,000 Value ($000) $1,184 Avg Close $13.78 Range $8.43 - $22.66

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	74,921	$1,209	$20.81	$16.13 - $26.01
Q4 2024	80,000	$1,862	$29.32	$22.37 - $40.26
Q4 2023	55,000	$1,184	$13.78	$8.43 - $22.66