SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

SILVERARC CAPITAL MANAGEMENT, LLC's Holding History (CIK: 0001816307)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 187,737 Value ($000) $6,150 Avg Close $26.13 Range $15.86 - $35.31

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	187,737	$6,150	$26.13	$15.86 - $35.31