Location: Boston, MA
CIK: 0001816307 · Show all filings
Period: Q2 2026 (← Previous)
Filing Date: Aug 13, 2026
Total Value: $962M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S | 206,234 | $55.01M | 5.7% | $266.72 | — | ORD SHS | K08588103 |
| ELVN | ENLIVEN THERAPEUTICS INC | 489,382 | $24.84M | 2.6% | $50.75 | — | COM | 29337E102 |
| SGMT | SAGIMET BIOSCIENCES INC | 2,927,698 | $22.63M | 2.4% | $7.73 | — | COM SER A | 786700104 |
| — | ARK ETF TR | 500,000 | $21.03M | 2.2% | — | — | PUT | 00214Q952 |
| DFTX | DEFINIUM THERAPEUTICS INC | 400,000 | $18.82M | 2.0% | $47.04 | — | COM SHS | 24477V105 |
| ALXO | ALX ONCOLOGY HLDGS INC | 5,744,757 | $11.89M | 1.2% | $2.07 | — | COM | 00166B105 |
| MANE | VERADERMICS INC | 95,000 | $11.68M | 1.2% | $122.94 | — | COMMON STOCK | 922967104 |
| AVLN | AVALYN PHARMACEUTICALS INC | 330,487 | $10.88M | 1.1% | $32.92 | — | COM SHS | 05348Y105 |
| ACRS | ACLARIS THERAPEUTICS INC | 1,946,482 | $10.3M | 1.1% | $5.29 | — | COM | 00461U105 |
| AVTX | AVALO THERAPEUTICS INC | 500,402 | $9.247M | 1.0% | $18.48 | — | COM NEW | 05338F306 |
| WGS | GENEDX HOLDINGS CORP | 122,269 | $8.394M | 0.9% | $68.65 | — | COM CL A | 81663L200 |
| — | ORIC PHARMACEUTICALS INC | 682,600 | $7.393M | 0.8% | — | — | CALL | 68622P909 |
| — | MONTE ROSA THERAPEUTICS INC | 300,000 | $7.26M | 0.8% | — | — | CALL | 61225M902 |
| SLDB | SOLID BIOSCIENCES INC | 668,450 | $6.678M | 0.7% | $9.99 | — | COM NEW | 83422E204 |
| — | ABIVAX SA | 50,000 | $6.663M | 0.7% | — | — | CALL | 00370M903 |
| ARTV | ARTIVA BIOTHERAPEUTICS INC | 525,000 | $5.093M | 0.5% | $9.70 | — | COM | 04317A107 |
| QURE | UNIQURE NV | 105,000 | $4.836M | 0.5% | $46.06 | — | SHS | N90064101 |
| RACC | RESEARCH ALLIANCE CORP III | 360,000 | $3.852M | 0.4% | $10.70 | — | ORD SHS CL A | G75226103 |
| KPTI | KARYOPHARM THERAPEUTICS INC | 297,460 | $2.906M | 0.3% | $9.77 | — | COM NEW | 48576U205 |
| — | KYMERA THERAPEUTICS INC | 25,000 | $2.867M | 0.3% | — | — | PUT | 501575954 |
| RVMD | REVOLUTION MEDICINES INC | 10,000 | $1.873M | 0.2% | $187.28 | — | COM | 76155X100 |
| — | ABSCI CORPORATION | 157,600 | $1.827M | 0.2% | — | — | PUT | 00091E959 |
| ACHV | ACHIEVE LIFE SCIENCE INC | 227,178 | $1.483M | 0.2% | $6.53 | — | COM | 004468500 |
| CNTB | CONNECT BIOPHARMA HLDGS LTD | 545,000 | $1.297M | 0.1% | $2.38 | — | SHS | G23549101 |
| CLRB | CELLECTAR BIOSCIENCES INC | 321,728 | $894K | 0.1% | $2.78 | — | COM NEW | 15117F880 |
| FHTX | FOGHORN THERAPEUTICS INC | 45,975 | $224K | 0.0% | $4.88 | — | COM | 344174107 |
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ORKA | ORUKA THERAPEUTICS INC | 352,802 (+133.8%) | $33.58M (+353.6%) | 3.5% | $68.34 | — | COM | 687604108 |
| IMVT | IMMUNOVANT INC | 619,096 (+49.5%) | $23.85M (+131.8%) | 2.5% | $30.32 | — | COM | 45258J102 |
| VCYT | VERACYTE INC | 318,001 (+77.0%) | $18.68M (+222.7%) | 1.9% | $44.89 | — | COM | 92337F107 |
| CELC | CELCUITY INC | 500,996 (+40.0%) | $52.41M (+28.3%) | 5.4% | $81.48 | — | COM | 15102K100 |
| CCCC | C4 THERAPEUTICS INC | 3,032,060 (+58.6%) | $14.16M (+181.6%) | 1.5% | $3.24 | — | COM STK | 12529R107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 311,461 (+1.8%) | $34.58M (+29.9%) | 3.6% | $75.31 | — | COM | 76243J105 |
| — | SYNDAX PHARMACEUTICALS INC | 693,600 (+116.8%) | $15.16M (+102.8%) | 1.6% | — | — | CALL | 87164F905 |
| TRVI | TREVI THERAPEUTICS INC | 678,095 (+32.7%) | $12.65M (+107.4%) | 1.3% | $7.27 | — | COM | 89532M101 |
| OVID | OVID THERAPEUTICS INC | 3,101,129 (+210.1%) | $8.342M (+275.8%) | 0.9% | $2.34 | — | COM | 690469101 |
| GH | GUARDANT HEALTH INC | 99,826 (+1.3%) | $14.98M (+64.6%) | 1.6% | $91.44 | — | COM | 40131M109 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 1,214,390 (+36.6%) | $26.55M (+27.8%) | 2.8% | $19.28 | — | COM | 87164F105 |
| IBIO | IBIO INC | 3,520,490 (+1457.7%) | $6.161M (+1334.8%) | 0.6% | $1.76 | — | COM NEW | 451033708 |
| CMPS | COMPASS PATHWAYS PLC | 503,382 (+67.8%) | $7.123M (+329.3%) | 0.7% | $9.01 | — | SPONSORED ADS | 20451W101 |
| CERS | CERUS CORP | 3,472,737 (+9.3%) | $10.14M (+75.4%) | 1.1% | $3.14 | — | COM | 157085101 |
| IMNM | IMMUNOME INC | 2,017,009 (+9.0%) | $42.74M (+5.6%) | 4.4% | $19.83 | — | COM | 45257U108 |
| SION | SIONNA THERAPEUTICS INC | 42,478 (+7.8%) | $1.869M (+18.2%) | 0.2% | $17.17 | — | COM | 829401108 |
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | SPDR SERIES TRUST | 825,000 | $105M | 11.0% | — | — | PUT | 78464A950 |
| KALV | KALVISTA PHARMACEUTICALS INC | 2,876,407 | $57.9M | 6.0% | $12.52 | — | — | 483497103 |
| NUVL | NUVALENT INC | 354,914 | $36.36M | 3.8% | $77.35 | — | — | 670703107 |
| ASND | ASCENDIS PHARMA A/S | 124,658 | $28.51M | 3.0% | $196.77 | — | — | 04351P101 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 466,345 | $18.52M | 1.9% | $24.95 | — | — | 152309100 |
| SRRK | SCHOLAR ROCK HLDG CORP | 339,613 | $16.7M | 1.7% | $45.48 | — | — | 80706P103 |
| CGON | CG ONCOLOGY INC | 166,349 | $11.26M | 1.2% | $24.86 | — | — | 156944100 |
| — | UNIQURE NV | 500,000 | $8.175M | 0.8% | — | — | CALL | N90064901 |
| — | CELCUITY INC | 54,500 | $6.221M | 0.6% | — | — | CALL | 15102K900 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 178,378 | $5.658M | 0.6% | $27.17 | — | — | 15117B202 |
| CYTK | CYTOKINETICS INC | 71,203 | $4.693M | 0.5% | $64.44 | — | — | 23282W605 |
| CLYM | CLIMB BIO INC | 684,908 | $4.692M | 0.5% | $5.00 | — | — | 28658R106 |
| CMPX | COMPASS THERAPEUTICS INC | 859,049 | $4.544M | 0.5% | $2.86 | — | — | 20454B104 |
| SRZN | SURROZEN INC | 144,255 | $4.202M | 0.4% | $16.18 | — | — | 86889P208 |
| ZURA | ZURA BIO LTD | 560,651 | $3.336M | 0.3% | $5.88 | — | — | G9TY5A101 |
| FULC | FULCRUM THERAPEUTICS INC | 419,949 | $3.221M | 0.3% | $10.19 | — | — | 359616109 |
| ANNX | ANNEXON INC | 496,461 | $2.75M | 0.3% | $5.75 | — | — | 03589W102 |
| MNPR | MONOPAR THERAPEUTICS INC | 43,488 | $2.383M | 0.2% | $62.79 | — | — | 61023L207 |
| NXTC | NEXTCURE INC | 176,057 | $1.88M | 0.2% | $10.36 | — | — | 65343E207 |
| NMRA | NEUMORA THERAPEUTICS INC. | 818,156 | $1.595M | 0.2% | $2.46 | — | — | 640979100 |
| EWTX | EDGEWISE THERAPEUTICS INC | 42,615 | $1.342M | 0.1% | $20.18 | — | — | 28036F105 |
| REPL | REPLIMUNE GROUP INC | 171,936 | $1.315M | 0.1% | $7.81 | — | — | 76029N106 |
| GENB | GENERATE BIOMEDICINES INC | 100,000 | $1.25M | 0.1% | $12.50 | — | — | 370920100 |
| — | COMPASS THERAPEUTICS INC | 172,400 | $912K | 0.1% | — | — | CALL | 20454B904 |
| RADX | RADIOPHARM THERANOSTICS LTD | 187,406 | $806K | 0.1% | $4.49 | — | — | 75041J101 |
| AARD | AARDVARK THERAPEUTICS INC | 33,684 | $127K | 0.0% | $10.73 | — | — | 002942100 |
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| URGN | UROGEN PHARMA LTD | 1,301,979 (-13.4%) | $47.91M (+77.3%) | 5.0% | $13.27 | — | COM | M96088105 |
| DNTH | DIANTHUS THERAPEUTICS INC | 390,000 (-40.4%) | $38.02M (-30.8%) | 4.0% | $26.43 | — | COM | 252828108 |
| KOD | KODIAK SCIENCES INC | 546,256 (-44.9%) | $21.28M (-43.7%) | 2.2% | $7.38 | — | COM | 50015M109 |
| ABVX | ABIVAX SA | 169,593 (-43.9%) | $22.6M (-32.9%) | 2.3% | $84.90 | — | SPONSORED ADS | 00370M103 |
| ALKS | ALKERMES PLC | 113,494 (-75.3%) | $5.947M (-63.5%) | 0.6% | $32.34 | — | SHS | G01767105 |
| ZBIO | ZENAS BIOPHARMA INC | 509,789 (-55.1%) | $12.94M (-41.7%) | 1.3% | $21.89 | — | COM | 98937L105 |
| ERAS | ERASCA INC | 1,263,026 (-31.8%) | $23.14M (-22.8%) | 2.4% | $4.46 | — | COM | 29479A108 |
| IRON | DISC MEDICINE INC | 82,800 (-57.8%) | $6.056M (-51.7%) | 0.6% | $74.04 | — | COM | 254604101 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 1,108,295 (-44.6%) | $26.82M (-18.6%) | 2.8% | $14.13 | — | COM | 61225M102 |
| ORIC | ORIC PHARMACEUTICALS INC | 738,873 (-32.8%) | $8.002M (-42.6%) | 0.8% | $6.76 | — | COM | 68622P109 |
| SYRE | SPYRE THERAPEUTICS INC | 59,959 (-67.9%) | $5.323M (-43.4%) | 0.6% | $26.13 | — | COM NEW | 00773J202 |
| INSM | INSMED INC | 34,438 (-3.9%) | $3.672M (-37.4%) | 0.4% | $56.86 | — | COM PAR $.01 | 457669307 |
| BNTC | BENITEC BIOPHARMA INC | 679,826 (-5.3%) | $9.096M (+19.0%) | 0.9% | $13.20 | — | COM NEW | 08205P209 |
| CBIO | CRESCENT BIOPHARMA INC. | 59,104 (-54.7%) | $1.064M (-55.6%) | 0.1% | $11.06 | — | COM | G2545C104 |
| PRAX | PRAXIS PRECISION MEDICINES I | 65,679 (-8.2%) | $21.99M (-4.6%) | 2.3% | $100.25 | — | COM NEW | 74006W207 |
| BIIB | BIOGEN INC | 48,101 (-5.6%) | $10.39M (+11.2%) | 1.1% | $135.17 | — | COM | 09062X103 |
| COGT | COGENT BIOSCIENCES INC | 1,280,707 (-2.5%) | $49.56M (-2.0%) | 5.2% | $18.51 | — | COM | 19240Q201 |
| CTNM | CONTINEUM THERAPEUTICS INC | 296,135 (-1.9%) | $4.854M (+23.2%) | 0.5% | $9.60 | — | CL A | 21217B100 |
| ABEO | ABEONA THERAPEUTICS INC | 610,407 (-5.9%) | $3.772M (+29.8%) | 0.4% | $5.72 | — | COM NEW | 00289Y206 |
| SVRA | SAVARA INC | 1,355,459 (-5.3%) | $8.35M (+6.9%) | 0.9% | $5.69 | — | COM | 805111101 |
| GUTS | FRACTYL HEALTH INC | 1,637,976 (-3.7%) | $1.301M (+67.0%) | 0.1% | $1.40 | — | COM | 35168W103 |
| ELUT | ELUTIA INC | 2,192,980 (-12.2%) | $2.148M (-18.1%) | 0.2% | $3.14 | — | CL A COM | 05479K106 |
| HLXC | HELIX ACQUISITION CORP III | 1,177,821 (-2.6%) | $12.53M (+2.0%) | 1.3% | $10.16 | — | USD CL A ORD SHS | G4444S107 |
| CGEN | COMPUGEN LTD | 3,184,257 (-4.0%) | $6.814M (-3.5%) | 0.7% | $1.61 | — | ORD | M25722105 |
| XENE | XENON PHARMACEUTICALS INC | 186,821 (-5.5%) | $11.28M (-1.9%) | 1.2% | $41.98 | — | COM | 98420N105 |
| TELA | TELA BIO INC | 2,137,201 (-5.4%) | $1.603M (+14.4%) | 0.2% | $4.46 | — | COM | 872381108 |
| ADGM | ADAGIO MED HLDGS INC | 224,360 (-11.0%) | $146K (-49.5%) | 0.0% | $1.19 | — | COM | 00534B100 |
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | FULCRUM THERAPEUTICS INC | 391,900 | $1.434M | 0.1% | — | — | CALL | 359616909 |
| CAMP | CAMP4 THERAPEUTICS CORP | 653,594 | $2.856M | 0.3% | $4.67 | — | COM | 13463J101 |
| PCVX | VAXCYTE INC | 145,000 | $8.429M | 0.9% | $32.81 | — | COM | 92243G108 |
| RCKTW | ROCKET PHARMACEUTICALS INC | 104,828 | $356 | 0.0% | $0.11 | — | *W EXP 09/02/202 | 77313F114 |