JADE BIOSCIENCES INC

Ticker: JBIO CUSIP: 008064206 Class: Common Stock

RTW INVESTMENTS, LP's Holding History (CIK: 0001493215)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,449,273 Value ($000) $22,362 Avg Close $11.73 Range $8.16 - $17.71

Q3 2025

Shares 1,449,273 Value ($000) $12,507 Avg Close $8.17 Range $6.67 - $11.33

Q2 2025

Shares 1,449,273 Value ($000) $14,478 Avg Close $33.31 Range $6.57 - $97.54

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,449,273	$22,362	$11.73	$8.16 - $17.71
Q3 2025	1,449,273	$12,507	$8.17	$6.67 - $11.33
Q2 2025	1,449,273	$14,478	$33.31	$6.57 - $97.54