JADE BIOSCIENCES INC

Ticker: JBIO CUSIP: 008064206 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 427,608 Value ($000) $6,598 Avg Close $11.73 Range $8.16 - $17.71

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	427,608	$6,598	$11.73	$8.16 - $17.71