AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

EcoR1 Capital, LLC's Holding History (CIK: 0001587114)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018

Shares 172,952 Value ($000) $14,144 Avg Close $77.29 Range $56.50 - $87.00

Q2 2017

Shares 23,300 Value ($000) $1,199 Avg Close $51.12 Range $45.11 - $59.58

Q1 2017

Shares 23,300 Value ($000) $1,361 Avg Close $47.94 Range $39.24 - $58.65

Q4 2016

Shares 23,300 Value ($000) $972 Avg Close $52.47 Range $40.59 - $67.74

Q3 2016

Shares 200,000 Value ($000) $10,564 Avg Close $43.55 Range $35.84 - $54.99

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2018	172,952	$14,144	$77.29	$56.50 - $87.00
Q2 2017	23,300	$1,199	$51.12	$45.11 - $59.58
Q1 2017	23,300	$1,361	$47.94	$39.24 - $58.65
Q4 2016	23,300	$972	$52.47	$40.59 - $67.74
Q3 2016	200,000	$10,564	$43.55	$35.84 - $54.99