AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

Squarepoint Ops LLC's Holding History (CIK: 0001642575)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 121,763 Value ($000) $3,314 Avg Close $35.08 Range $22.24 - $46.00

Q1 2025

Shares 37,920 Value ($000) $1,111 Avg Close $33.17 Range $28.31 - $36.17

Q4 2024

Shares 162,415 Value ($000) $5,337 Avg Close $46.98 Range $32.31 - $62.58

Q2 2024

Shares 6,622 Value ($000) $286 Avg Close $36.09 Range $27.14 - $49.06

Q1 2024

Shares 112,066 Value ($000) $3,277 Avg Close $26.78 Range $20.96 - $35.50

Q4 2023

Shares 33,926 Value ($000) $756 Avg Close $22.41 Range $19.80 - $24.89

Q3 2023

Shares 17,107 Value ($000) $423 Avg Close $26.45 Range $24.04 - $28.65

Q1 2023

Shares 10,956 Value ($000) $252 Avg Close $26.56 Range $21.07 - $31.56

Q4 2022

Shares 25,731 Value ($000) $723 Avg Close $28.18 Range $24.70 - $31.87

Q3 2022

Shares 17,168 Value ($000) $486 Avg Close $26.82 Range $19.43 - $34.76

Q2 2022

Shares 101,191 Value ($000) $2,243 Avg Close $22.59 Range $16.75 - $31.79

Q1 2022

Shares 34,372 Value ($000) $1,001 Avg Close $30.55 Range $26.51 - $35.12

Q4 2021

Shares 42,629 Value ($000) $1,401 Avg Close $40.25 Range $29.21 - $50.98

Q4 2020

Shares 103,454 Value ($000) $4,483 Avg Close $39.54 Range $32.47 - $49.98

Q3 2020

Shares 131,406 Value ($000) $4,599 Avg Close $43.83 Range $33.45 - $56.75

Q1 2020

Shares 24,630 Value ($000) $874 Avg Close $46.21 Range $27.77 - $54.68

Q4 2019

Shares 112,265 Value ($000) $5,361 Avg Close $37.79 Range $28.36 - $50.74

Q2 2019

Shares 17,477 Value ($000) $872 Avg Close $53.45 Range $45.43 - $68.89

Q4 2018

Shares 5,782 Value ($000) $267 Avg Close $61.72 Range $41.63 - $79.17

Q3 2018

Shares 30,434 Value ($000) $2,347 Avg Close $80.45 Range $70.47 - $94.39

Q2 2018

Shares 10,181 Value ($000) $858 Avg Close $87.20 Range $72.14 - $99.82

Q4 2017

Shares 17,088 Value ($000) $977 Avg Close $62.92 Range $51.62 - $72.73

Q3 2017

Shares 4,161 Value ($000) $278 Avg Close $60.07 Range $50.91 - $67.72

Q2 2017

Shares 5,161 Value ($000) $266 Avg Close $51.12 Range $45.11 - $59.58

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	121,763	$3,314	$35.08	$22.24 - $46.00
Q1 2025	37,920	$1,111	$33.17	$28.31 - $36.17
Q4 2024	162,415	$5,337	$46.98	$32.31 - $62.58
Q2 2024	6,622	$286	$36.09	$27.14 - $49.06
Q1 2024	112,066	$3,277	$26.78	$20.96 - $35.50
Q4 2023	33,926	$756	$22.41	$19.80 - $24.89
Q3 2023	17,107	$423	$26.45	$24.04 - $28.65
Q1 2023	10,956	$252	$26.56	$21.07 - $31.56
Q4 2022	25,731	$723	$28.18	$24.70 - $31.87
Q3 2022	17,168	$486	$26.82	$19.43 - $34.76
Q2 2022	101,191	$2,243	$22.59	$16.75 - $31.79
Q1 2022	34,372	$1,001	$30.55	$26.51 - $35.12
Q4 2021	42,629	$1,401	$40.25	$29.21 - $50.98
Q4 2020	103,454	$4,483	$39.54	$32.47 - $49.98
Q3 2020	131,406	$4,599	$43.83	$33.45 - $56.75
Q1 2020	24,630	$874	$46.21	$27.77 - $54.68
Q4 2019	112,265	$5,361	$37.79	$28.36 - $50.74
Q2 2019	17,477	$872	$53.45	$45.43 - $68.89
Q4 2018	5,782	$267	$61.72	$41.63 - $79.17
Q3 2018	30,434	$2,347	$80.45	$70.47 - $94.39
Q2 2018	10,181	$858	$87.20	$72.14 - $99.82
Q4 2017	17,088	$977	$62.92	$51.62 - $72.73
Q3 2017	4,161	$278	$60.07	$50.91 - $67.72
Q2 2017	5,161	$266	$51.12	$45.11 - $59.58