ANAPTYSBIO INC

Ticker: ANAB CUSIP: 032724106 Class: Common Stock

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 76,300 Value ($000) $3,699 Avg Close $38.98 Range $29.48 - $52.47

Q3 2025

Shares 123,300 Value ($000) $3,775 Avg Close $22.95 Range $17.11 - $32.50

Q2 2025

Shares 263,086 Value ($000) $5,841 Avg Close $20.93 Range $15.40 - $24.86

Q1 2025

Shares 338,700 Value ($000) $6,296 Avg Close $16.68 Range $12.21 - $21.57

Q4 2024

Shares 193,200 Value ($000) $2,558 Avg Close $24.22 Range $12.51 - $36.54

Q3 2024

Shares 200,400 Value ($000) $6,713 Avg Close $34.16 Range $23.72 - $41.31

Q2 2024

Shares 152,702 Value ($000) $3,827 Avg Close $23.28 Range $18.49 - $27.02

Q1 2024

Shares 100,200 Value ($000) $2 Avg Close $23.68 Range $20.64 - $27.50

Q4 2023

Shares 95,600 Value ($000) $2 Avg Close $17.25 Range $13.36 - $22.39

Q3 2023

Shares 92,700 Value ($000) $2 Avg Close $19.08 Range $16.51 - $20.80

Q2 2023

Shares 58,000 Value ($000) $1 Avg Close $20.27 Range $18.01 - $23.05

Q1 2023

Shares 71,600 Value ($000) $2 Avg Close $24.30 Range $20.51 - $31.14

Q2 2022

Shares 29,600 Value ($000) $601 Avg Close $22.15 Range $18.20 - $26.89

Q1 2022

Shares 58,300 Value ($000) $1,442 Avg Close $30.26 Range $24.03 - $36.06

Q4 2021

Shares 34,600 Value ($000) $1,202 Avg Close $31.71 Range $26.46 - $37.89

Q3 2021

Shares 68,700 Value ($000) $1,863 Avg Close $25.38 Range $22.77 - $28.40

Q2 2021

Shares 224,300 Value ($000) $5,816 Avg Close $23.97 Range $19.91 - $26.80

Q1 2021

Shares 230,782 Value ($000) $4,973 Avg Close $25.24 Range $17.72 - $35.85

Q4 2020

Shares 134,600 Value ($000) $2,894 Avg Close $24.28 Range $14.55 - $31.29

Q3 2020

Shares 26,800 Value ($000) $395 Avg Close $18.04 Range $13.92 - $23.75

Q1 2020

Shares 293,500 Value ($000) $4,147 Avg Close $15.17 Range $12.06 - $18.70

Q4 2019

Shares 92,400 Value ($000) $1,502 Avg Close $23.65 Range $10.00 - $39.48

Q1 2018

Shares 59,400 Value ($000) $6,182 Avg Close $112.70 Range $91.01 - $134.00

Q4 2017

Shares 127,500 Value ($000) $12,842 Avg Close $73.61 Range $34.56 - $102.63

Q3 2017

Shares 97,800 Value ($000) $3,418 Avg Close $26.97 Range $20.12 - $37.62

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	76,300	$3,699	$38.98	$29.48 - $52.47
Q3 2025	123,300	$3,775	$22.95	$17.11 - $32.50
Q2 2025	263,086	$5,841	$20.93	$15.40 - $24.86
Q1 2025	338,700	$6,296	$16.68	$12.21 - $21.57
Q4 2024	193,200	$2,558	$24.22	$12.51 - $36.54
Q3 2024	200,400	$6,713	$34.16	$23.72 - $41.31
Q2 2024	152,702	$3,827	$23.28	$18.49 - $27.02
Q1 2024	100,200	$2	$23.68	$20.64 - $27.50
Q4 2023	95,600	$2	$17.25	$13.36 - $22.39
Q3 2023	92,700	$2	$19.08	$16.51 - $20.80
Q2 2023	58,000	$1	$20.27	$18.01 - $23.05
Q1 2023	71,600	$2	$24.30	$20.51 - $31.14
Q2 2022	29,600	$601	$22.15	$18.20 - $26.89
Q1 2022	58,300	$1,442	$30.26	$24.03 - $36.06
Q4 2021	34,600	$1,202	$31.71	$26.46 - $37.89
Q3 2021	68,700	$1,863	$25.38	$22.77 - $28.40
Q2 2021	224,300	$5,816	$23.97	$19.91 - $26.80
Q1 2021	230,782	$4,973	$25.24	$17.72 - $35.85
Q4 2020	134,600	$2,894	$24.28	$14.55 - $31.29
Q3 2020	26,800	$395	$18.04	$13.92 - $23.75
Q1 2020	293,500	$4,147	$15.17	$12.06 - $18.70
Q4 2019	92,400	$1,502	$23.65	$10.00 - $39.48
Q1 2018	59,400	$6,182	$112.70	$91.01 - $134.00
Q4 2017	127,500	$12,842	$73.61	$34.56 - $102.63
Q3 2017	97,800	$3,418	$26.97	$20.12 - $37.62