APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

RTW INVESTMENTS, LP's Holding History (CIK: 0001493215)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 7,666,764 Value ($000) $192,589 Avg Close $23.46 Range $18.75 - $30.48

Q1 2022

Shares 51,194 Value ($000) $2,601 Avg Close $44.15 Range $33.50 - $54.51

Q4 2021

Shares 1,990,404 Value ($000) $94,106 Avg Close $39.37 Range $30.17 - $50.31

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	7,666,764	$192,589	$23.46	$18.75 - $30.48
Q1 2022	51,194	$2,601	$44.15	$33.50 - $54.51
Q4 2021	1,990,404	$94,106	$39.37	$30.17 - $50.31