APOGEE THERAPEUTICS INC

Ticker: APGE CUSIP: 03770N101 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q2 2025

Shares 594,994 Value ($000) $25,841 Avg Close $38.04 Range $26.20 - $44.65

Q1 2025

Shares 594,994 Value ($000) $22,229 Avg Close $38.66 Range $29.10 - $50.56

Q4 2024

Shares 747,325 Value ($000) $33,854 Avg Close $51.00 Range $41.85 - $63.50

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2025	594,994	$25,841	$38.04	$26.20 - $44.65
Q1 2025	594,994	$22,229	$38.66	$29.10 - $50.56
Q4 2024	747,325	$33,854	$51.00	$41.85 - $63.50