ARROWHEAD PHARMACEUTICALS IN

Ticker: ARWR CUSIP: 04280A100 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 12,496 Value ($000) $431 Avg Close $21.98 Range $14.30 - $34.61

Q2 2025

Shares 202,996 Value ($000) $3,207 Avg Close $14.35 Range $9.57 - $17.49

Q1 2025

Shares 277,550 Value ($000) $3,536 Avg Close $18.18 Range $12.14 - $21.84

Q4 2024

Shares 197,550 Value ($000) $3,714 Avg Close $20.59 Range $17.05 - $27.34

Q2 2024

Shares 48,175 Value ($000) $1,252 Avg Close $24.57 Range $21.39 - $28.50

Q4 2023

Shares 144,899 Value ($000) $4,434 Avg Close $26.56 Range $20.67 - $31.68

Q3 2016

Shares 100,000 Value ($000) $735 Avg Close $6.48 Range $5.29 - $8.22

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	12,496	$431	$21.98	$14.30 - $34.61
Q2 2025	202,996	$3,207	$14.35	$9.57 - $17.49
Q1 2025	277,550	$3,536	$18.18	$12.14 - $21.84
Q4 2024	197,550	$3,714	$20.59	$17.05 - $27.34
Q2 2024	48,175	$1,252	$24.57	$21.39 - $28.50
Q4 2023	144,899	$4,434	$26.56	$20.67 - $31.68
Q3 2016	100,000	$735	$6.48	$5.29 - $8.22