AVIDITY BIOSCIENCES INC

Ticker: RNAM CUSIP: 05370A108 Class: EQTY

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 1,285,610 Value ($000) $56,014 Avg Close $40.43 Range $27.70 - $51.40

Q2 2025

Shares 1,110,610 Value ($000) $31,541 Avg Close $29.81 Range $21.51 - $38.00

Q1 2025

Shares 1,110,610 Value ($000) $32,785 Avg Close $31.14 Range $26.74 - $36.38

Q4 2024

Shares 1,127,295 Value ($000) $32,782 Avg Close $41.79 Range $28.32 - $56.00

Q3 2024

Shares 1,440,736 Value ($000) $66,173 Avg Close $43.40 Range $36.63 - $48.80

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	1,285,610	$56,014	$40.43	$27.70 - $51.40
Q2 2025	1,110,610	$31,541	$29.81	$21.51 - $38.00
Q1 2025	1,110,610	$32,785	$31.14	$26.74 - $36.38
Q4 2024	1,127,295	$32,782	$41.79	$28.32 - $56.00
Q3 2024	1,440,736	$66,173	$43.40	$36.63 - $48.80