BIOCRYST PHARMACEUTICALS INC

Ticker: BCRX CUSIP: 09058V103 Class: Common Stock

GREAT POINT PARTNERS LLC's Holding History (CIK: 0001281446)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 5,955,762 Value ($000) $48,480 Avg Close $8.56 Range $7.10 - $9.95

Q4 2018

Shares 7,622,256 Value ($000) $61,512 Avg Close $7.78 Range $6.43 - $9.71

Q3 2018

Shares 7,978,275 Value ($000) $60,874 Avg Close $6.72 Range $5.41 - $8.13

Q2 2018

Shares 7,478,275 Value ($000) $42,851 Avg Close $5.50 Range $4.53 - $6.67

Q1 2018

Shares 7,478,275 Value ($000) $35,671,000 Avg Close $5.14 Range $4.25 - $5.92

Q4 2017

Shares 4,751,883 Value ($000) $23,332 Avg Close $4.84 Range $4.12 - $5.35

Q3 2017

Shares 1,637,332 Value ($000) $8,580 Avg Close $5.12 Range $3.95 - $6.22

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	5,955,762	$48,480	$8.56	$7.10 - $9.95
Q4 2018	7,622,256	$61,512	$7.78	$6.43 - $9.71
Q3 2018	7,978,275	$60,874	$6.72	$5.41 - $8.13
Q2 2018	7,478,275	$42,851	$5.50	$4.53 - $6.67
Q1 2018	7,478,275	$35,671,000	$5.14	$4.25 - $5.92
Q4 2017	4,751,883	$23,332	$4.84	$4.12 - $5.35
Q3 2017	1,637,332	$8,580	$5.12	$3.95 - $6.22