CASSAVA SCIENCES INC

Institution	Shares	Value ($000)
GSA CAPITAL PARTNERS LLP	287,879	$1
D. E. Shaw & Co., Inc.	469,326	$929
Point72 Asset Management, L.P.	299,579	$593
Jump Financial, LLC	91,620	$181
OMERS ADMINISTRATION Corp	83,900	$166
CANADA PENSION PLAN INVESTMENT BOARD	144,100	$285
Connor, Clark & Lunn Investment Management Ltd.	100,577	$199
DIMENSIONAL FUND ADVISORS LP	140,057	$277
Lighthouse Investment Partners, LLC	29,520	$58
Invesco Ltd.	18,120	$36
Smartleaf Asset Management LLC	1,369	$3
Virtu Financial LLC	48,832	$0
FLAGSHIP HARBOR ADVISORS, LLC	620	$1
SageView Advisory Group, LLC	110	$0
PRICE T ROWE ASSOCIATES INC /MD/	31,368	$0
HRT FINANCIAL LP	23,192	$0
Laurel Wealth Advisors LLC	17	$0
Larson Financial Group LLC	10	$0
HANTZ FINANCIAL SERVICES, INC.	50	$0

Increased Positions (21)

Caitong International Asset Management Co., Ltd

Value ($000) $27 (+284.8%) Shares 13,606 (+465.5%)

Headlands Technologies LLC

Value ($000) $101 (+36.9%) Shares 50,866 (+101.2%)

JANE STREET GROUP, LLC

Value ($000) $1,016 (+78.5%) Shares 513,137 (+162.4%)

SUSQUEHANNA INTERNATIONAL GROUP, LLP

Value ($000) $1,045 (-6.0%) Shares 528,018 (+38.2%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $1,272 (-22.6%) Shares 642,401 (+13.7%)

VANGUARD GROUP INC

Value ($000) $4,704 (-29.4%) Shares 2,375,589 (+3.8%)

GROUP ONE TRADING, L.P.

Value ($000) $534 (-9.1%) Shares 269,470 (+33.7%)

MARSHALL WACE, LLP

Value ($000) $4,188 (-30.2%) Shares 2,115,307 (+2.6%)

FEDERATED HERMES, INC.

Value ($000) $181 (+43.8%) Shares 91,479 (+111.3%)

JACOBS LEVY EQUITY MANAGEMENT, INC

Value ($000) $489 (-25.2%) Shares 246,987 (+9.9%)

Engineers Gate Manager LP

Value ($000) $63 (+50.4%) Shares 31,654 (+121.1%)

NORTHERN TRUST CORP

Value ($000) $295 (-22.6%) Shares 149,194 (+13.7%)

Graham Capital Management, L.P.

Value ($000) $255 (-25.7%) Shares 128,703 (+9.1%)

AMERICAN CENTURY COMPANIES INC

Value ($000) $106 (-6.8%) Shares 53,367 (+37.0%)

RAYMOND JAMES FINANCIAL INC

Value ($000) $60 (+22.2%) Shares 30,464 (+79.5%)

Bank of New York Mellon Corp

Value ($000) $41 (+30.7%) Shares 20,481 (+92.1%)

GEODE CAPITAL MANAGEMENT, LLC

Value ($000) $1,081 (-30.9%) Shares 545,969 (+1.5%)

MGO ONE SEVEN LLC

Value ($000) $42 (-13.1%) Shares 21,262 (+27.8%)

SIMPLEX TRADING, LLC

Value ($000) $343 (+72808.1%) Shares 173,065 (+7.0%)

LPL Financial LLC

Value ($000) $86 (-29.8%) Shares 43,427 (+3.1%)

Institution	Prev Shares	Curr Shares	Change
Caitong International Asset Management Co., Ltd	2,406	13,606	+11,200 (+465.5%)
Headlands Technologies LLC	25,283	50,866	+25,583 (+101.2%)
JANE STREET GROUP, LLC	195,571	513,137	+317,566 (+162.4%)
SUSQUEHANNA INTERNATIONAL GROUP, LLP	382,018	528,018	+146,000 (+38.2%)
TWO SIGMA INVESTMENTS, LP	564,998	642,401	+77,403 (+13.7%)
VANGUARD GROUP INC	2,289,523	2,375,589	+86,066 (+3.8%)
GROUP ONE TRADING, L.P.	201,616	269,470	+67,854 (+33.7%)
MARSHALL WACE, LLP	2,061,286	2,115,307	+54,021 (+2.6%)
FEDERATED HERMES, INC.	43,285	91,479	+48,194 (+111.3%)
JACOBS LEVY EQUITY MANAGEMENT, INC	224,658	246,987	+22,329 (+9.9%)
Engineers Gate Manager LP	14,319	31,654	+17,335 (+121.1%)
NORTHERN TRUST CORP	131,170	149,194	+18,024 (+13.7%)
Graham Capital Management, L.P.	117,927	128,703	+10,776 (+9.1%)
AMERICAN CENTURY COMPANIES INC	38,961	53,367	+14,406 (+37.0%)
RAYMOND JAMES FINANCIAL INC	16,968	30,464	+13,496 (+79.5%)
Bank of New York Mellon Corp	10,663	20,481	+9,818 (+92.1%)
GEODE CAPITAL MANAGEMENT, LLC	537,901	545,969	+8,068 (+1.5%)
MGO ONE SEVEN LLC	16,639	21,262	+4,623 (+27.8%)
SIMPLEX TRADING, LLC	161,678	173,065	+11,387 (+7.0%)
LPL Financial LLC	42,117	43,427	+1,310 (+3.1%)

Decreased Positions (28)

XTX Topco Ltd

Value ($000) $69 (-73.2%) Shares 34,928 (-60.6%)

JPMORGAN CHASE & CO

Value ($000) $0 (-100.0%) Shares 13 (-100.0%)

GOLDMAN SACHS GROUP INC

Value ($000) $65 (-95.3%) Shares 32,989 (-93.0%)

MORGAN STANLEY

Value ($000) $139 (-86.3%) Shares 70,439 (-79.9%)

BARCLAYS PLC

Value ($000) $96 (-95.6%) Shares 48,462 (-35.2%)

UBS Group AG

Value ($000) $59 (-89.2%) Shares 29,869 (-84.2%)

ROYAL BANK OF CANADA

Value ($000) $10 (-95.3%) Shares 5,498 (-92.5%)

MILLENNIUM MANAGEMENT LLC

Value ($000) $543 (-41.5%) Shares 274,399 (-14.0%)

Walleye Trading LLC

Value ($000) $18 (-82.5%) Shares 9,178 (-74.3%)

BANK OF AMERICA CORP /DE/

Value ($000) $27 (-67.4%) Shares 13,531 (-52.1%)

Apollon Wealth Management, LLC

Value ($000) $78 (-41.9%) Shares 39,538 (-14.6%)

BNP PARIBAS ARBITRAGE, SA

Value ($000) $22 (-56.5%) Shares 11,009 (-36.0%)

Verition Fund Management LLC

Value ($000) $54 (-41.4%) Shares 27,244 (-13.9%)

WELLS FARGO & COMPANY/MN

Value ($000) $32 (-44.2%) Shares 16,304 (-18.0%)

OSAIC HOLDINGS, INC.

Value ($000) $63 (-21.4%) Shares 31,757 (-8.6%)

CITIGROUP INC

Value ($000) $0 (-98.3%) Shares 62 (-97.5%)

FMR LLC

Value ($000) $15 (-41.0%) Shares 7,492 (-13.3%)

EverSource Wealth Advisors, LLC

Value ($000) $6 (-43.9%) Shares 3,110 (-17.5%)

Tower Research Capital LLC (TRC)

Value ($000) $10 (-38.3%) Shares 4,918 (-9.3%)

Fortis Capital Advisors, LLC

Value ($000) $24 (-33.6%) Shares 12,259 (-2.4%)

Institution	Prev Shares	Curr Shares	Change
XTX Topco Ltd	88,563	34,928	-53,635 (-60.6%)
JPMORGAN CHASE & CO	565,439	13	-565,426 (-100.0%)
GOLDMAN SACHS GROUP INC	472,860	32,989	-439,871 (-93.0%)
MORGAN STANLEY	350,060	70,439	-279,621 (-79.9%)
BARCLAYS PLC	74,747	48,462	-26,285 (-35.2%)
UBS Group AG	188,993	29,869	-159,124 (-84.2%)
ROYAL BANK OF CANADA	73,239	5,498	-67,741 (-92.5%)
MILLENNIUM MANAGEMENT LLC	318,886	274,399	-44,487 (-14.0%)
Walleye Trading LLC	35,653	9,178	-26,475 (-74.3%)
BANK OF AMERICA CORP /DE/	28,228	13,531	-14,697 (-52.1%)
Apollon Wealth Management, LLC	46,271	39,538	-6,733 (-14.6%)
BNP PARIBAS ARBITRAGE, SA	17,210	11,009	-6,201 (-36.0%)
Verition Fund Management LLC	31,637	27,244	-4,393 (-13.9%)
WELLS FARGO & COMPANY/MN	19,883	16,304	-3,579 (-18.0%)
OSAIC HOLDINGS, INC.	34,764	31,757	-3,007 (-8.6%)
CITIGROUP INC	2,436	62	-2,374 (-97.5%)
FMR LLC	8,641	7,492	-1,149 (-13.3%)
EverSource Wealth Advisors, LLC	3,769	3,110	-659 (-17.5%)
Tower Research Capital LLC (TRC)	5,423	4,918	-505 (-9.3%)
Fortis Capital Advisors, LLC	12,563	12,259	-304 (-2.4%)

Exited Positions (16)

ACT CAPITAL MANAGEMENT, LLC

Value ($000) $142 Shares 3,400

GMT CAPITAL CORP

Value ($000) $1,310 Shares 450,100

683 Capital Management, LLC

Value ($000) $1,237 Shares 425,000

Catalyst Funds Management Pty Ltd

Value ($000) $129 Shares 44,500

ADAR1 Capital Management, LLC

Value ($000) $236 Shares 81,000

Voleon Capital Management LP

Value ($000) $414 Shares 142,385

EAGLE WEALTH STRATEGIES LLC

Value ($000) $29 Shares 10,000

Brookstone Capital Management

Value ($000) $49 Shares 16,753

CITADEL ADVISORS LLC

Value ($000) $40 Shares 13,864

Squarepoint Ops LLC

Value ($000) $36 Shares 12,396

Advisory Services Network, LLC

Value ($000) $1 Shares 300

SALEM INVESTMENT COUNSELORS INC

Value ($000) $1 Shares 275

MATHER GROUP, LLC.

Value ($000) $1 Shares 250

Allworth Financial LP

Value ($000) $1 Shares 185

PRINCIPAL SECURITIES, INC.

Value ($000) $0 Shares 25

Optiver Holding B.V.

Value ($000) $0 Shares 12

Institution	Prev Shares	Prev Value ($000)
ACT CAPITAL MANAGEMENT, LLC	3,400	$142
GMT CAPITAL CORP	450,100	$1,310
683 Capital Management, LLC	425,000	$1,237
Catalyst Funds Management Pty Ltd	44,500	$129
ADAR1 Capital Management, LLC	81,000	$236
Voleon Capital Management LP	142,385	$414
EAGLE WEALTH STRATEGIES LLC	10,000	$29
Brookstone Capital Management	16,753	$49
CITADEL ADVISORS LLC	13,864	$40
Squarepoint Ops LLC	12,396	$36
Advisory Services Network, LLC	300	$1
SALEM INVESTMENT COUNSELORS INC	275	$1
MATHER GROUP, LLC.	250	$1
Allworth Financial LP	185	$1
PRINCIPAL SECURITIES, INC.	25	$0
Optiver Holding B.V.	12	$0